Protein Alignment ItgaPS5 and itga6b

DIOPT Version :9

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: NP_001013466.1
• Gene: itga6b / 541320
• ZFINID: ZDB-GENE-050320-5
• Length: 1085
• Species: Danio rerio
• Alignment Length: 1152
• Identity: 271/1152 - (23%)
• Similarity: 446/1152 - (38%)
• Gaps: 297/1152 - (25%)

  Fly    44 SSYFGYSLV----IRPTS---IFVGAPRAQSTLESQGSINETGAVYRCP--LASGSCSHYVLNDK 99
            :|.||:|:.    :||..   :.||:|:|::....:..|  ||.:|.|.  :...||...:.:::
Zfish    38 NSLFGFSMAMHRQLRPADKRMLLVGSPKAKALPNQRSKI--TGGLYNCDINIPGQSCQRVMFDNE 100

  Fly   100 -----LNKQFQWLGGSMD----GGTKDTDKLLVCAPRF----FVPKNKNYGQMRGICYWVRDTVA 151
                 .||:.||:|.::.    ||     |:||||.|:    ||...:....:.|.||
Zfish   101 ENLQTENKENQWMGVTVQSQGPGG-----KILVCAHRYQRRLFVGSVQELRDLTGRCY------- 153

  Fly   152 DTPPLSDVRTISLIP-------------SQAEEHF-MLELGLSAHVTDDNSGFLIGAPGVRSWKG 202
               .||:..||:.|.             ::..|.| ..:.|:||..|.|....:.||||..:|||
Zfish   154 ---VLSEDVTINEISDEDGGDWMFCNGRNRGHERFGSCQQGMSATFTKDYHYLVFGAPGAYNWKG 215

  Fly   203 SVLVHR------GEDLAAQGSYAV---KMLDSWDWVKNHFTYVGYALSSGYFSSNNRTSLLYVTT 258
            .|.:.:      .:|:...|.|.|   ..||:........:|:|::|.||...: .|..|..|..
Zfish   216 IVRLEQKNTSLFDKDIFDDGPYEVGDENRLDAELVPVPANSYLGFSLDSGKMLT-KRGQLTIVAG 279

  Fly   259 APSSVLNTGKAYIF----DVVGEIVRKLHVFHGEQLGEYFGYSVVAEDLNGDGLTDVVVSAPLNA 319
            ||.:  |...|.:.    :....::...:...|..|...|||.:...|:||||..|:||.||...
Zfish   280 APRA--NHSGAVVLLKKDEAKSSLLTAEYTLEGSGLASSFGYDLAVLDINGDGWQDIVVGAPQYF 342

  Fly   320 LGDSYDVGAIYVFIN-KGLF-KFEKKIIRLPLSSGARFGSSLSKVGDINHDGYNDLAVGAPFAGN 382
            :.|....|||||::| :|.: |...|.|..|..|  .||.::..:||:|.|||.|:||.||:..|
Zfish   343 IKDGDIGGAIYVYLNEEGAWDKITPKRIDGPAYS--MFGLAVENMGDVNLDGYQDVAVSAPYDSN 405

  Fly   383 GA--VFIFLGSEHGLRDEPSQRLDAPSREPGPYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEA 445
            ||  |.||.||..||:  .||.|....     :...:||..|:...|:|.|.:.|||||:. :::
Zfish   406 GAGNVIIFHGSPQGLK--KSQVLGGKD-----HNVKLFGYSLAGNMDLDRNNYPDLAIGSL-SDS 462

  Fly   446 VYLYRAYPVVKIHATVRSESR-------------------------AIRPEQETITVTACYRLET 485
            |::||:..|:.|..||.:..:                         :::|:....|:...|.:..
Zfish   463 VFVYRSRSVINIEKTVTTTPKELDLTKKNCNNGNNICLDVKACFKFSVKPKTYNPTLKVAYTIRV 527

  Fly   486 TSKARQMQQQELTFRMTIDELLQRVSFAPMRTNEVSFQAQAGLSG----SC--RNFSV------- 537
            .|:.:::            .|..||.|.|...|:........|.|    ||  ||..:
Zfish   528 ESERKKL------------NLPSRVIFNPRSNNDYESTGIVELKGQGTESCIYRNLMLQETLKDK 580

  Fly   538 --GVHYTGGIFTPIDLELHYELAKKIPHSHEAFCESCAVVDPLEPKYATGTLSFM-TGCAA-HVC 598
              |:        ||::.:......|......|......::|..:.......:.|: .||.| |:|
Zfish   581 LRGI--------PIEVSVEILNQNKRRRRQAALPNLLPILDSNQEATTVAMVQFIKEGCGADHLC 637

  Fly   599 VSDLQLS----SKDVNSSFIF-----GSLEVLSFS--------YEITNSGEPAYVAQFNVTSSAR 646
            .|||||.    :::.|....|     ..:.:||.|        .:..|.||.||..|...:....
Zfish   638 QSDLQLQYKFHTREPNKDNFFPFDEEKGVPILSLSDQKEIALEIKAVNLGEDAYETQLTASFPKS 702

  Fly   647 LPFAKVPG-------NCRVRHEVMLCDLNGGRALARGDSESLTIIFDVTQLSGQSLTIEAAVSSA 704
            |.::.|..       :|.|.......|.:.|....:....:..||.....:|..:..||.
Zfish   703 LSYSAVRTQSGDKQISCLVNQNGSQADCDLGNPFKKDAQTTFYIILSTGGISLDTTEIEI----- 762

  Fly   705 GMDQNPKDNTMSTTISLREYAEIDA------------SG----------GPIDGHIALKEYPYSA 747
                   |..:.||...::...:.|            ||          |.:.|..|:|   .:.
Zfish   763 -------DLKLKTTSEQKQLQAVKAKAIVKIQLLLSLSGVAKPSQVFFTGEVKGESAMK---VAG 817

  Fly   748 EVNN--SYEFKSHGPSIIDELTVYVDVPIAYTVTGSAGIKSIFNISSLQMQATHGSE----LVPI 806
            :|.:  .|||:          ...:|.|          :||....|.:.....|.|:    |..:
Zfish   818 DVGSPIDYEFR----------VTNLDKP----------LKSFGRASMIIQWPKHNSQGKWLLYLM 862

  Fly   807 KL------------YDQTNTLAKEYPLEDSSRRANRKRREL-----QQDQYAIMPDVNISDILTK 854
            |:            .|:.|.|.    |::.|  .:|.:||:     .:.:.|...|.....:|:.
Zfish   863 KMTSTGLDSLSCTNSDEVNKLG----LKELS--VSRTKREVGETSAAEGKTAFFTDKRKYTLLSC 921

  Fly   855 ENLPANRTLV--LDCLRGNWTICVRSQMRVQLKPEQPIDLRISF-----KVDLNDFV--NTFDYL 910
            ::.....|.:  |..:..|..|.:|:.:           ...:|     |::..|.:  .:.|:.
Zfish   922 DDGAECITFICPLTGMDSNAVISLRAYL-----------WNATFLEDYAKLNYVDIIAKASLDFK 975

  Fly   911 VIFTNVEMFKEGDSTSIALKRNLKPNVIFNYSETPLPIWYIILSLIAGHLLLGAMTYILYKLRFF 975
            ...||:::..|.....:.:....|   :..|.  .:|.|.|:::::.|.||||.:.::|:|..||
Zfish   976 TTATNIQLKNEPSQVRVTVFPERK---VAQYG--GMPWWVILVAILLGLLLLGLLVFLLWKCGFF 1035

  Fly   976 KRGKKEE------LKRLLEEHR-----------SETKEPATDCEGNQ 1005
            ||.|.::      ..|:..|.|           ||.|:..|....|:
Zfish  1036 KRSKYDDSVPSYNAVRIKREERDNLSGKDEMDSSEKKQWMTSWNENE 1082

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	VCBS	302..375	CDD:338792	32/74 (43%)
		Int_alpha	351..403	CDD:214549	26/53 (49%)
		Int_alpha	417..463	CDD:214549	18/45 (40%)
		Integrin_alpha2	451..836	CDD:337057	90/495 (18%)
itga6b	NP_001013466.1	Int_alpha	37..98	CDD:214549	17/61 (28%)
		Int_alpha	254..>292	CDD:214549	12/40 (30%)
		Int_alpha	315..365	CDD:214549	21/49 (43%)
		Int_alpha	374..425	CDD:214549	25/54 (46%)
		Integrin_alpha2	468..932	CDD:285619	94/524 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574967
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840