Protein Alignment ItgaPS5 and itga2b

DIOPT Version :9

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: NP_001003857.1
• Gene: itga2b / 445380
• ZFINID: ZDB-GENE-051031-1
• Length: 1037
• Species: Danio rerio
• Alignment Length: 1132
• Identity: 277/1132 - (24%)
• Similarity: 477/1132 - (42%)
• Gaps: 223/1132 - (19%)

  Fly     4 LLFLIFLALKYQSNAMNFSPLPNRVIDAPKHLKTRMIQVRSSYFGYSLVI-----RPTSIFVGAP 63
            ||||..|.........|.......|...|:          .||||:|:..     :..|:.||||
Zfish     9 LLFLSILIFTNHIRGFNLDLNQYTVFSGPE----------DSYFGFSVDFYQSSSKSVSVVVGAP 63

  Fly    64 RAQSTLESQGSINETGAVYRCPLASGSCSHYVLN-----DK----------LNKQFQWLGGSMDG 113
            ||.:   :|..::..|:|:.||.|:...|...||     |:          .:|..||||.|:
Zfish    64 RANT---NQSGVSHGGSVFMCPWATRGQSCQTLNFDQKGDENITFGNMLLMAHKSNQWLGASV-- 123

  Fly   114 GTKDTDKLLVCAPRF----FVPKNKNYGQMRGICYWVR---DTVADTPPLSDVRTISLIPSQAEE 171
             ....:.:|.|||.|    .|.:.:......|.|..:.   ..:|:..|..:....::......:
Zfish   124 -RTYNNYILACAPLFHWNVLVDQEEAMNTPVGNCQLLNMKTGELANYAPCREEYVYAIYTRGYPD 187

  Fly   172 HFMLELGLSAHVTDDNSGFLIGAPGVRSWKGSVLVHRGEDLAAQGS------------YAVKMLD 224
            ....|.|.:..:| .|...::||||...::|.::.....::.:.||            ...:..|
Zfish   188 RRYCEAGFTTDIT-KNGRVVLGAPGGYYFQGQIITASLVNIMSSGSSFTPKHSMNGETKTPQRRD 251

  Fly   225 SWDWVKNHFTYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGKAYIFDVVGEIVRKLHVFHGEQ 289
            .:|      .|:||::::|.|:::|...  ||...|:.:...|...|.:.....::.:....|.|
Zfish   252 YYD------LYLGYSVAAGKFNNDNIPD--YVVGVPNDLHTAGSVKIINGATVPLQIMKAISGTQ 308

  Fly   290 LGEYFGYSVVAEDLNGDGLTDVVVSAPL--NALGDS--YDVGAIYVFINKGLFKFEKKIIRLPLS 350
            :..|||:||...|:|.||..|:::.|||  ..|...  .:||.:||::.:..|.|..:..::...
Zfish   309 IASYFGHSVAVTDINRDGWDDILIGAPLFMEQLSTQKFREVGQVYVYLQRNDFSFASRPNQILAG 373

  Fly   351 SGA--RFGSSLSKVGDINHDGYNDLAVGAP-FAGNGAVFIFLGSEHGLRDEPSQRLDAPSR---E 409
            :.|  ||||:::.:||::|||:||:||||| ....|.|||:||...||..:..|.:::|.|   :
Zfish   374 TYAYGRFGSAIAPLGDLDHDGFNDVAVGAPGSVDGGKVFIYLGKSGGLSTQYVQVIESPFRSLID 438

  Fly   410 PGPYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEAVYLYRAYPVVKIHATVRSESRAIRPEQE- 473
            |     .|||..:..|:|||.||:.||.|||.||..|..|||..||:..|.:......:.||.:
Zfish   439 P-----PMFGFSIRGGTDIDDNGYPDLIIGAWGASKVVTYRAQAVVRTQARLSFFPDLLNPEDKF 498

  Fly   474 -----------TITVTACYRLETTSKARQMQQQELTFRMTIDELLQRV--------SFAPMRTNE 519
                       ..|:.||.|:   |..|..||......:.:|.:.|.:        |..|....:
Zfish   499 CQLQQSGTYITCFTIMACIRV---SGHRIPQQIVFNTELQLDRMKQSMARRTLLLDSNQPYTNFQ 560

  Fly   520 VSFQAQAGLSGSCRNFSVGVHYTGGIF----TPIDLELHYELAKKIPHSHEAFCESCAVVDPLEP 580
            :|....:  ...||||:.   |....|    :||.:.::|.||    .|..|.....:|
Zfish   561 ISVDRNS--RDVCRNFTA---YLLPEFKDKLSPIFISVNYSLA----DSQNAVLHGQSV------ 610

  Fly   581 KYATGTLSFMTGCAA-HVCVSDLQLSSKDVNSSFIFGSLEVLSFSYEITNSGEPAYVAQFNVTSS 644
              |.|....:..|.. :||:.||||.:.......:.|.........|..|.||.||..:..::..
Zfish   611 --AVGQTRIILNCGPDNVCIPDLQLKAVTSTEPILIGDENPALLIIEAENQGEGAYETELYISPP 673

  Fly   645 ARLPFAKVPGN--------CRVRHE----VMLCDLNGGRALARGDSESLTIIF---DVTQLSGQS 694
            |...:..|..|        |..:.|    :::|||  |..|..|......:.|   |:.|:...
Zfish   674 ANTHYQGVLSNHEDFSALVCGQKKENGSVIVVCDL--GNPLEAGQQLKAGLYFSMGDLEQVENH- 735

  Fly   695 LTIEAAVSSAGMDQNPKDNTMSTTISLREYAEIDASG--GPIDGHIAL-----KEYPYSAE---- 748
            :|.:..:.|.. .||...|.:...:::...|.::..|  .|:|..:.:     |:||...:
Zfish   736 ITFQMQIRSKN-SQNSDSNLVQLQVNVTAVASLEMRGVSSPVDCVLPISKWESKDYPEDLDEVGP 799

  Fly   749 -VNNSYEFKSHGPSIID-ELTVYVDVPIAYTVTGSAGIKSIFNISSLQMQA--THGSELVPIKLY 809
             :.:.||.::.|||.:: :||  ::.|::   ...:.:..:|..:|.::.:  |..:.:.|.:|.
Zfish   800 LIEHVYELRNRGPSPVNVKLT--LEFPVS---QNESYLLYVFANASEELISCQTDYANIDPRRLV 859

  Fly   810 DQ--TN-TLAKEYPLEDSSRRANRKRRELQQDQYAIMPDVNISDILTKENLPANRTLVLDCLRGN 871
            .|  || |:|:.:..  :.|..::|....||.|:.:  .||.|.        :.:.:|.||:...
Zfish   860 KQESTNITVAEVHHF--NKRDLSQKTENEQQWQHTV--HVNCSS--------SEQCVVFDCVAAG 912

  Fly   872 W------TICVRSQMRVQLKPEQPIDLRISFKVDLNDFVN-----TFDYLVIFTNVEMFKEGDST 925
            .      .:.|.|::.||...::|             :||     |..|.|:  ||....:.|..
Zfish   913 LQRDERAIVRVMSRLWVQTFLKRP-------------YVNYVLHSTAHYEVM--NVPSKIQPDVL 962

  Fly   926 SIALKRNLKPNVIFNY--SETPLPIWYIILSLIAGHLLLGAMTYILYKLRFFKRGKKEELKRLLE 988
            ... |......:|:..  .:..:|:|:|::|::||.|||.|::.|.:|:.||||
Zfish   963 PTG-KAETHTKIIWRSPDGQEEVPLWWIVVSIVAGLLLLAALSTIFWKMGFFKR----------- 1015

  Fly   989 EHRSETKEPATDCEGNQEEINVEMHSD 1015
                 .:.|:.:.:.:.:::..:::.|
Zfish  1016 -----NRPPSDNDDDDDDDVTQQLNGD 1037

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	VCBS	302..375	CDD:338792	27/78 (35%)
		Int_alpha	351..403	CDD:214549	26/54 (48%)
		Int_alpha	417..463	CDD:214549	23/45 (51%)
		Integrin_alpha2	451..836	CDD:337057	95/442 (21%)
itga2b	NP_001003857.1	Int_alpha	256..>293	CDD:214549	11/38 (29%)
		Int_alpha	309..>358	CDD:214549	18/48 (38%)
		Int_alpha	376..429	CDD:214549	26/52 (50%)
		Int_alpha	441..>480	CDD:214549	21/38 (55%)
		Integrin_alpha2	475..908	CDD:285619	102/473 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574942
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840