Protein Alignment ItgaPS5 and itga9

DIOPT Version :9

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: NP_001311427.1
• Gene: itga9 / 394012
• ZFINID: ZDB-GENE-040426-1129
• Length: 1032
• Species: Danio rerio
• Alignment Length: 1123
• Identity: 276/1123 - (24%)
• Similarity: 477/1123 - (42%)
• Gaps: 250/1123 - (22%)

  Fly    24 LPNRVIDAPKHLKTRMIQV-----------------------------RSSYFGYSLV--IRPTS 57
            :|||:.:    |.||.|:.                             .:::||||::  :...:
Zfish     1 MPNRMTE----LSTRKIRALDVFVCLCSVSLAYSFNIDLQYPVVFRGPDATFFGYSVLEHVHDNT 61

  Fly    58 --IFVGAPRAQSTLESQGSINETGAVYRCPLASG------------------SCSHYVLNDKLNK 102
              |.||||||.|:..|  |:...||||:|.:.:.                  ||......|:.:
Zfish    62 RWIVVGAPRANSSFSS--SVQSPGAVYKCRIRNNPEQRCTEMDLGRGNKQRESCGKTCQGDRND- 123

  Fly   103 QFQWLGGSMDGGTKDTDKLLVCAPRFFVPKN----KNYGQMRGICYWVRDTVADTPPLSDVRTIS 163
              :|:|.|:....|...|:|.||.|:   ||    ..|....|.|..:       |.....::..
Zfish   124 --EWMGVSLARQNKPNGKILACAHRW---KNVYYESEYILPHGYCSII-------PANLQGKSQP 176

  Fly   164 LIP-------SQAEEHFMLELGLSAHVTDDNSGFLIGAPGVRSWKGSVLVHRGEDLAAQGSYAVK 221
            |||       :..|||...:.|::...|::.  .::||||...|.|:|.|.   ::.:...|
Zfish   177 LIPCYEDHKKTYGEEHGSCQAGIAGVFTEEL--VVMGAPGSYYWTGTVKVF---NMTSNTHY--- 233

  Fly   222 MLDSWDWVKNHFTYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGKAYIFDVVGEIVRKLHVFH 286
            .|:..|...:.::|:|||:::|:|||.|...:  ...||.. ...||.|:|.:.|..:.|:....
Zfish   234 NLNQDDLSPHRYSYLGYAVTAGHFSSPNTIDV--AAGAPQD-SGGGKVYVFRIEGTALVKIFQAS 295

  Fly   287 GEQLGEYFGYSVVAEDLNGDGLTDVVVSAPLNALGDSYDVGAIYVFINKGLFKFEK-KIIRLPLS 350
            |:.:|.|||.|:.|.|||.|||:|::|.||:::  :..|.|.:.|:::.|....|: .|:....:
Zfish   296 GKMMGSYFGSSLCAVDLNADGLSDLLVGAPMHS--EIRDEGQVSVYLSSGNGVMEEVAILNGDNA 358

  Fly   351 SGARFGSSLSKVGDINHDGYNDLAVGAPFAGN--GAVFIFLGSEHGLRDEPSQRLDAPSREPGPY 413
            ..|.||..::.:|||:.|||.|:|:|||...:  |||:|:.|...|:.::.|.||...|..|
Zfish   359 YNAHFGECITSLGDIDDDGYQDVAIGAPEEDDYGGAVYIYHGDARGIVNKYSMRLSGRSINP--- 420

  Fly   414 GAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEAVYLYRAYPVVKIHATVRSESRAIRPEQETITVT 478
            ...||||.:|...|:||||:.|:.|||..|::|.|.|:.||:.:..::      ..|....|||.
Zfish   421 TLQMFGQSISGNVDMDGNGYPDVTIGAFMADSVVLLRSRPVISVDVSI------FLPVSINITVP 479

  Fly   479 ACYR-----------LETTSKARQMQQQ-ELTFRMTIDELLQRVSFAPMRTNEVSFQAQAGLSGS 531
            .|:.           :..:.:.:.:... ||.:.:|.|...:.....|        :|..|..|.
Zfish   480 QCHEGPQHLNCFNVTVCMSFRGKHVPGHIELLYNLTADSDKRHKGLPP--------RAYFGNGGE 536

  Fly   532 -----CRNFSVGVH------YTG-------GIFTPIDLELHYELAKKIPHSHEAFCESCAVVDPL 578
                 .:.|::.:|      ||.       .:|..|..|..|.|.|.|...|:.     ..:.||
Zfish   537 QTGVVSQRFNLEIHRQQCHQYTAFVRKEVKDVFAAIVFEAAYSLGKHIVDEHQD-----RDLPPL 596

  Fly   579 EP--------KYATGTLS-FMTGCAAHVCVSDLQ------LSSKDVNSSFIFGSLEVLSFSYEIT 628
            .|        |.|....: |...|.:..|.:|||      ||.:.::|....|.::.:|.:..|:
Zfish   597 SPILRWKKGEKIAAKNETWFEKNCLSDDCAADLQLHGKLLLSGRYISSHLALGGVKNVSLNLTIS 661

  Fly   629 NSGEPAYVAQFNVTSSARLPFAKVPGNCRVRHE----VMLCDL-----NGGRALARGDSE-SLTI 683
            |:|:.||........|..:.:.    |...|.|    .||.:|     :.|....|..:: .::.
Zfish   662 NAGDDAYDTNIYFNFSKEVHYI----NFLQREEKGISCMLVELDFLKCSVGFPFMRAQTKYHISA 722

  Fly   684 IFDVTQLSGQSLT----IEAAVSSAGMDQNPKDNTMSTTISLREYAEIDAS------------GG 732
            :||.::|||::.|    :.|..::...|....|||:..:|.|  ..|:|.:            |.
Zfish   723 LFDTSRLSGENETLLFLVHARSANPEHDNTLHDNTLELSIPL--VHEVDTTITGVVNPTSFVYGN 785

  Fly   733 PID--GHIALKEYPYSAE-VNNSYEFKSHGPSIIDELTVYVDVPIAYTVTGSAGIKSIFNISSLQ 794
            .:|  ..:.|::...|.: :|.:::..::|||.:....  ||:.|.:.:.||.  ..:|:|...|
Zfish   786 SVDRSRFVQLEDMECSFQPLNFTFQVINNGPSRLPGSR--VDIRIPHRLAGSG--PEMFHIIDTQ 846

  Fly   795 MQATHGSELVPIKLYDQTNTLAKEYPLEDSSRRANRKRRELQQDQYAIMPDVNISDILTKENLPA 859
            :....|                      :.:...|.|...:.||:.:|..  .|....||..
Zfish   847 VSDARG----------------------NCTWHRNPKPCTIPQDKESIFH--TIFAFFTKSG--- 884

  Fly   860 NRTLVLDCLR-GNWTICVRSQMRVQLKPE-QPIDLRISFKVDL--NDFVNTFDYLVIFTNVEMFK 920
              ..||||.| |...:.:...:..|.|.| ..||:::....::  .|..:...: |...:|::
Zfish   885 --RKVLDCDRPGRACLTISCSLGSQAKEEATSIDVQMLLNTEILQRDSSSVIQF-VTRGHVQL-- 944

  Fly   921 EGDSTSIALKRNLKPNVIF----NYSETP---LPIWYIILSLIAGHLLLGAMTYILYKLRFFKRG 978
              |..::.:...|..::..    .:|:.|   :..|.|.:||:.|.|:...:..:|:|:.||:|.
Zfish   945 --DDRTVEVSSGLPDDISLVMEALHSQEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRH 1007

  Fly   979 KKEELKRLLEEHRSETKE 996
            .:|.::  .|::|.::.|
Zfish  1008 YREIIE--AEKNRKDSDE 1023

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	VCBS	302..375	CDD:338792	26/73 (36%)
		Int_alpha	351..403	CDD:214549	21/53 (40%)
		Int_alpha	417..463	CDD:214549	20/45 (44%)
		Integrin_alpha2	451..836	CDD:337057	91/458 (20%)
itga9	NP_001311427.1	Int_alpha	45..93	CDD:214549	19/49 (39%)
		Int_alpha	245..293	CDD:214549	17/50 (34%)
		Int_alpha	299..345	CDD:214549	20/47 (43%)
		Int_alpha	360..413	CDD:214549	21/52 (40%)
		Int_alpha	423..>465	CDD:214549	20/41 (49%)
		Integrin_alpha2	458..902	CDD:285619	103/501 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574945
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23220
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950