Sequence 1: | NP_611808.2 | Gene: | ItgaPS5 / 37732 | FlyBaseID: | FBgn0034880 | Length: | 1018 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001139280.1 | Gene: | ITGAM / 3684 | HGNCID: | 6149 | Length: | 1153 | Species: | Homo sapiens |
Alignment Length: | 1304 | Identity: | 253/1304 - (19%) |
---|---|---|---|
Similarity: | 431/1304 - (33%) | Gaps: | 464/1304 - (35%) |
- Green bases have known domain annotations that are detailed below.
Fly 3 RLLFLIFLALKY-----QSNAMNFSPLPNRVIDAPKHLKTRMIQVRSSYFGYSLV-IRPTSIFVG 61
Fly 62 APRAQSTLESQGSINETGAVYRCPLASGSCSHYVLNDKLNKQFQWLGGSMDGGTKDTDKLLVCAP 126
Fly 127 RFFVPKNKNYGQMRGICYWVRDTVADTPPL------------SDVRTI-----SLIP-------- 166
Fly 167 ------------------SQAEEHFMLELGLSAHVTDDNSGFLI-----------GAPGVR---- 198
Fly 199 ------------SWKGSVLVHRGE----------------------------------------- 210
Fly 211 -----------------------------------------------DLAAQGSYA--------V 220
Fly 221 KMLDSWDWVKNHFTYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGKAYIFDVVGEIVRK---- 281
Fly 282 --------LHV------------------FHGEQLGEYFGYSVVAEDLNGDGLTDVVVSAPLNAL 320
Fly 321 GDSYDVGAIYVF-INKGLFKFEKKIIRLPLSSG-------------------ARFGSSLSKVGDI 365
Fly 366 NHDGYNDLAVGAPFA--GNGAVFIFLG-SEHGLRDEPSQRLDAPSREPGPYGAHMFGQGLSRGSD 427
Fly 428 IDGNGFNDLAIGAPGAEAVYLYRAYPVVKIHATVRSESRAIRPE-----------QETITVTACY 481
Fly 482 RLETTSKARQMQ---QQELTFRMTID--ELLQRVSFAPMRTNEVSFQAQA-GLSGSCRNFSVGV- 539
Fly 540 HYTGGIFTPIDLELHYELAKKIPHSHEAFCESCAVVDPLEPKYATGTLSFMTGCA-AHVCVSDLQ 603
Fly 604 LSSKDVNSSFIFGSLEVL------SFSYEIT--NSGEPAYVAQFNVTSSARLPFAKV-------- 652
Fly 653 ---------------------PGNCRVRHEVMLCDLNGGRALARGDSESLTIIFDVTQLS--GQS 694
Fly 695 LTIEAAVSSAGMDQNPKDNTMSTTISLREYAEIDASGGPIDGHIALKEYPYSAEVNNSYEFKSHG 759
Fly 760 PSIIDELTVYVDVPI---AYTVTGSAGIKSIFNISSLQMQATHGSELVPIKLYDQTNTLAKEYPL 821
Fly 822 EDSSRRANRKRRELQQDQYAIMPDVNISDIL-----TKENLPAN--------RTLVLDCLRGNWT 873
Fly 874 ICVRSQMRVQLKP----EQPIDLRISFKVDLNDFVNT-FDYLVIFTNVE-MFKEGDSTSI----A 928
Fly 929 LKRNLKPNVIFNYSETPLPIWYIILSLIAGHLLLGAMTYILYKLRFFKRGKKEELKRLLEEHRSE 993
Fly 994 TKEP 997 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ItgaPS5 | NP_611808.2 | VCBS | 302..375 | CDD:338792 | 20/92 (22%) |
Int_alpha | 351..403 | CDD:214549 | 23/73 (32%) | ||
Int_alpha | 417..463 | CDD:214549 | 19/45 (42%) | ||
Integrin_alpha2 | 451..836 | CDD:337057 | 79/445 (18%) | ||
ITGAM | NP_001139280.1 | FG-GAP 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803 | 18..75 | 20/81 (25%) | |
FG-GAP 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803 | 76..135 | 12/60 (20%) | |||
vWA_integrins_alpha_subunit | 149..324 | CDD:238746 | 17/174 (10%) | ||
FG-GAP 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803 | 339..390 | 8/60 (13%) | |||
FG-GAP 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803 | 391..442 | 7/53 (13%) | |||
Int_alpha | 453..>495 | CDD:214549 | 13/58 (22%) | ||
FG-GAP 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803 | 507..565 | 20/57 (35%) | |||
Int_alpha | 517..563 | CDD:214549 | 19/45 (42%) | ||
FG-GAP 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803 | 570..630 | 22/64 (34%) | |||
Integrin_alpha2 | 615..979 | CDD:285619 | 79/441 (18%) | ||
Integrin_alpha | 1130..1144 | CDD:278771 | 7/17 (41%) | ||
GFFKR motif | 1132..1136 | 2/3 (67%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165142016 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR23220 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.940 |