Protein Alignment ItgaPS5 and Itga3

DIOPT Version :10

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: NP_001359143.1
• Gene: Itga3 / 360606
• RGDID: 1310333
• Length: 1067
• Species: Rattus norvegicus
• Alignment Length: 1119
• Identity: 281/1119 - (25%)
• Similarity: 449/1119 - (40%)
• Gaps: 271/1119 - (24%)

  Fly    34 HLKTRMIQVR-----SSYFGYSLVI-RPTS------IFVGAPRAQSTLESQGSINETGAVYRCPL 86
            :|.|:.:.|:     .|.||||:.: |.|.      :..||||..:.  .....|.|||||.|||
  Rat    34 NLDTKFLVVKEAVNPGSLFGYSVALHRQTERQQRYLLLAGAPRDLAV--DDDYTNRTGAVYLCPL 96

  Fly    87 AS--GSC-----------SHYVLNDKLNKQFQWLGGSMDGGTKDTDKLLVCAPRF---FVPKNKN 135
            .:  ..|           .|:::.|      .|||.:: .......::||||.|:   .....::
  Rat    97 TALKNDCERMDISEKSDPDHHIIED------MWLGVTV-ASQGPAGRVLVCAHRYTKVLWSGLED 154

  Fly   136 YGQMRGICYWVRDTVADTPPLSDVRTI--SLIPSQAE--EHFMLELGLSAHVTDDNSGFLIGAPG 196
            ..:|.|.|| ||.......|..|.:|.  .:..|..:  :..|.:||.|...|.:...|  ||||
  Rat   155 QRRMVGKCY-VRGNDLQLDPGDDWQTYHNEMCNSNTDYLQTGMCQLGTSGGFTQNTVYF--GAPG 216

  Fly   197 VRSWKGSVLVHRGEDLAAQGSYAVKMLDSWDWVKNHF--------TYVGYALSSGYFSSNNRTSL 253
            ..:|||:             ||.::..| ||..:..:        .|:||.:..|       :::
  Rat   217 AYNWKGN-------------SYMIQRKD-WDLSEYSYRGSEDQGNLYIGYTMQVG-------SAI 260

  Fly   254 LY------VTTAPSSVLNTGKAYIF--DVVGEIVRKLHVFHGEQLGEYFGYSVVAEDLNGDGLTD 310
            |:      ||.||.. .:.|..::.  :..|::.|: .|..|.|:|.|||.::...|||.||..|
  Rat   261 LHPSEITLVTGAPRH-QHMGAVFLLKQESGGDLQRR-QVLKGTQVGAYFGSAIALADLNNDGWQD 323

  Fly   311 VVVSAPLNALGDSYDVGAIYVFINKGLFKF-EKKIIRLPLSSGARFGSSLSKVGDINHDGYNDLA 374
            ::|.||..........||:|||:|:....| ::..:.|...|.:.||.|::.:||||.||:.|:|
  Rat   324 LLVGAPYYFERKEEVGGAVYVFMNQAGTSFPDQPSLLLHGPSRSAFGISVASIGDINQDGFQDIA 388

  Fly   375 VGAPFAGNGAVFIFLGSEHGLRDEPSQRLDAPSREPGPYGAHMFGQGLSRGSDIDGNGFNDLAIG 439
            |||||.|.|.|:|:..|..||..:|.|.:...:.  |..|...||..||...|:|.|.:.||.:|
  Rat   389 VGAPFEGLGKVYIYHSSSGGLLKQPQQIIHGETL--GLPGLATFGYSLSGKMDVDENLYPDLLVG 451

  Fly   440 APGAEAVYLYRAYPVVKI-HATVRSESRAIRPEQETITVTACYRLE-----TTSKARQMQQQELT 498
            :. ::.:.|.||.||:.| |.|:.:....:.|  ...|||:|.::|     ..|......::.:|
  Rat   452 SL-SDHIVLLRARPVINILHRTLVARPAVLDP--SLCTVTSCVQVELCFAYNQSAGNPNYRRNIT 513

  Fly   499 FRMTI----DELLQRVSFAPMRTNEVSFQAQAGLSGSCRNFSVGVHYTGGIFT------------ 547
            ...|:    |....|:.||                   |:.|...|   |.|:
  Rat   514 LAYTVEADRDRRPPRLRFA-------------------RSQSSVFH---GFFSMPETHCQTLELL 556

  Fly   548 ----------PIDLELHYELAKKIP-------HSHEAFCESCAVVDPLEPKYATGTLSFMTGCAA 595
                      ||.:.::|.|..::|       .|.:|:    .|::..:.......:.|...|..
  Rat   557 LMDNVRDKLRPIVITMNYSLPLRMPDRLKLGLRSLDAY----PVLNQAQAMENHTEVHFQKECGP 617

  Fly   596 -HVCVSDLQLSSKDVNSSFIFGSLEVLS------------FSYEITNS------GEPAYVA--QF 639
             :.|.|:||:     .::|:...|:.||            .|..:|||      ||.|:.|  ..
  Rat   618 DNKCDSNLQM-----RAAFVSEQLQPLSRLQYSRDTKKLFLSINVTNSPSRQRAGEDAHEALLTL 677

  Fly   640 NVTSSARLPFAKVPGNCRVRHEVMLCDLNGGRALARGDSESLTIIFDVT--QLSGQSLTIEAAVS 702
            .|:|:..|...:..|.|:......:|:|  |....|.....|.|.|:||  .|..:.|.....:|
  Rat   678 EVSSALLLSSVRPAGTCQANETNTVCEL--GNPFKRNQRMELLIAFEVTGVTLHTRDLRAHLQLS 740

  Fly   703 SAGMDQNPK--------DNTMSTTISLREYAEIDASGGPIDGHIALKEYPYSAEVNN--SYEFK- 756
            ::....|.:        |.|:..::||..:.......|.:.|..|:|..   .:|.:  .|||:
  Rat   741 TSSHQDNLQPMFLTLQVDYTLQASLSLMNHRLQSFFSGTVMGEAAMKTV---KDVGSPLKYEFQV 802

  Fly   757 ---SHGPSIIDELTVYVDVPIAYTVTGSAGIK-----SIFNISSLQMQATHGSELVPIKLYDQTN 813
               ..|.:.:..|.:.::.|  |.||....:.     :|.:..|...| .||:.:.|:.|
  Rat   803 SPVGDGLAALGTLVLGLEWP--YEVTNGKWLLYPTEITIHSNGSWPCQ-PHGNLVNPLNL----- 859

  Fly   814 TLAKE--YPLEDSSRRANRKRRELQQDQYAIMPDVNISDILTKENLPANRTLVLDCLRGN----W 872
            ||:..  .||.     ..|:||:|........|.|.::  ..|:   |....||.|..|.    |
  Rat   860 TLSDPGVKPLS-----PQRRRRQLDPGGDQGPPPVTLA--AAKK---AKSETVLTCSNGRARCVW 914

  Fly   873 TIC----------VRSQMRVQLKPEQPIDLRISFKVDLNDF----VNTFDYLVIFTNVEMFKEGD 923
            ..|          |..:.||         ...:|..|..||    |:.:..|.:.|::......:
  Rat   915 LECPLPDASNITNVTVKARV---------WNSTFIEDYKDFDRVRVDGWATLFLRTSIPTINMEN 970

  Fly   924 ST---SIALKRNLKPNVIFNYSETP--LPIWYIILSLIAGHLLLGAMTYILYKLRFFKRGK---- 979
            .|   |:.:...|       ..|.|  :.:|.:::::.||.||||.:..:|:|..|||..:
  Rat   971 KTTWFSVDIDSEL-------VEELPAEIELWLVLVAVGAGLLLLGLIIILLWKCDFFKPTRYYRI 1028

  Fly   980 --KEELKRLLEEHR 991
              |....|:.||.|
  Rat  1029 MPKYHAVRIREEDR 1042

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	FG-GAP	294..332	CDD:460357	14/37 (38%)
		Int_alpha	351..403	CDD:214549	26/51 (51%)
		Int_alpha	417..463	CDD:214549	18/46 (39%)
		Integrin_alpha2	453..837	CDD:462478	100/466 (21%)
Itga3	NP_001359143.1	Int_alpha	48..108	CDD:214549	21/61 (34%)
		Int_alpha	304..352	CDD:214549	19/47 (40%)
		Int_alpha	367..417	CDD:214549	25/49 (51%)
		Integrin_alpha2	463..917	CDD:462478	109/509 (21%)