Protein Alignment ItgaPS5 and Itga11

DIOPT Version :10

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: NP_001400722.1
• Gene: Itga11 / 315744
• RGDID: 1311711
• Length: 1188
• Species: Rattus norvegicus
• Alignment Length: 1300
• Identity: 294/1300 - (22%)
• Similarity: 444/1300 - (34%)
• Gaps: 478/1300 - (36%)

  Fly    16 SNAMNFSPLPNRVIDAPKHLKTRMIQVRSSYFGYSLVIRPTS----IFVGAPRAQSTLESQGSIN 76
            ::..|......|||..|.          :::|||::.....|    :.||||     ||:.|. .
  Rat    20 TDTFNMDTRNPRVIAGPS----------AAFFGYTVQQHDISGKKWLVVGAP-----LETNGH-Q 68

  Fly    77 ETGAVYRCPLASGSCSHYVLNDKLN------------KQFQWLGGSMDGGTKDTDKLLVCAP--- 126
            :||.||:||:..|:|:      |||            |....||.|:....||: ..|.|:|
  Rat    69 KTGDVYKCPVTQGNCT------KLNLGRVTLSNVSERKDNMRLGLSLATNPKDS-SFLACSPLWS 126

  Fly   127 --------------------RF---FVP-----------------KNKNY--------------- 136
                                ||   ..|                 .|..|
  Rat   127 HECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWVEVQHFLIEILTK 191

  Fly   137 -----GQMR-GICYW---------------VRDTVA----------------------------- 151
                 ||:: ||..:               |:|.|.
  Rat   192 FYIGPGQIQVGIVQYGEDAVHEFHLNDYKSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQK 256

  Fly   152 -------------------DTPPLSDV-------------------------------RTISLIP 166
                               |:|.|..|                               ..|..|.
  Rat   257 GGRKGAKKVMIVITDGESHDSPDLEKVIRQSEKDNVTRYAVAVLGYYNRRGINPETFLNEIKYIA 321

  Fly   167 SQAEE-HF------------------------------------MLELGLSAHVTDDNSGFLIGA 194
            |..:: ||                                    |.:.|.|:||.:|  |.|:||
  Rat   322 SDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVED--GVLLGA 384

  Fly   195 PGVRSWKGSVL--VHRGEDLAAQGSYAVKMLDSWDWVKNHFTYVGYALSSGYFSSNNRTSLLYVT 257
            .|...|.|:||  ...|:.:..:.||..:..:.   :|||..|:||.::|...|...|   :||.
  Rat   385 VGAYDWNGAVLKETSAGKVIPLRESYLKEFPEE---LKNHAAYLGYTVTSVVSSKQGR---VYVA 443

  Fly   258 TAPSSVLNTGKAYIFDVVGEIVRKLH-VFHGEQLGEYFGYSVVAEDLNGDGLTDV-VVSAPLNAL 320
            .|| ...:|||..:|.:.......:| ...|||:|.|||..:.:.|:|.|.:||| :|.||: ..
  Rat   444 GAP-RFNHTGKVILFSIHTNRSLTIHQALRGEQIGSYFGSEITSVDINNDRVTDVLLVGAPM-YF 506

  Fly   321 GDSYDVGAIYVF-INKGLFKFEKKIIRLPLSSGARFGSSLSKVGDINHDGYNDLAVGAPF--AGN 382
            .:..:.|.:||: :.:..|.|...:........|||||.::.|.|:|.|.|||:.||||.  :..
  Rat   507 SEGRERGKVYVYNLRQNRFVFNGTLKDSHSYQNARFGSCIASVQDLNQDSYNDVVVGAPLEDSHR 571

  Fly   383 GAVFIFLGSEHGLRDEPSQRLDAPSREPG--PYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEA 445
            ||::||.|.:..:..:|.||:.|....||  .:|..:.||     .|::.:|..|||:||.| .|
  Rat   572 GAIYIFHGFQTNILKKPVQRISASELAPGLQHFGCSIHGQ-----LDLNEDGLVDLAVGALG-NA 630

  Fly   446 VYLYRAYPVVKIHATVRSESRAIR----------------------------PEQETITVTACYR 482
            |.|: |.|||:|:|::..|...|.                            |...|.||...|.
  Rat   631 VVLW-ARPVVQINASLHFEPSKINIFHKDCKRNGRDATCLAAFLCFGPIFLAPHFHTATVGIRYN 694

  Fly   483 LETTSKARQMQQQELTFRMTIDELLQRVSFAPMRTNEVSFQAQAGLSGS--CRNFSVGVHYTGGI 545
             .|..:.|.|.      |..:||      .|...||.....:    ||.  |:..:..|..|...
  Rat   695 -ATMDERRYMP------RAHLDE------GADQFTNRAVLLS----SGQEHCQRINFHVLDTADY 742

  Fly   546 FTPIDLELHYELAKKIPHSHEAFCESCAVVDPLEPKYATGTLSFMTGC--AAHVCVSDLQLSSK- 607
            ..|:...:.|.|...         :...::|...|.....::.|..||  ..| ||.||.|.::
  Rat   743 VKPVAFSVEYSLEDP---------DHGPMLDNGWPTTLRVSVPFWNGCNEDEH-CVPDLVLDARS 797

  Fly   608 ------------------DVNSSFIFGSLEVLSFSYEIT-----------NSGEPAYVAQFNVTS 643
                              |.:|..:  |.:...|..|.|           |.||.||.|..|::.
  Rat   798 DLPTAMEYCQQVLRRPAQDCSSYTL--SFDTTVFIIESTRRRVAVEATLENRGENAYSAVLNISQ 860

  Fly   644 SARLPFAK-------------VPGNCRVRHEVMLCDLN------GGRALARGDSESLTIIFDVTQ 689
            |..|.||.             |....|:..:|  |:::      ..:...|.|.|....:|
  Rat   861 SENLQFASLIQKDDSDNSIECVNEERRLHKKV--CNVSYPFFRAKAKVAFRLDFEFSKSVF---- 919

  Fly   690 LSGQSLTIEAAVSSAGMDQNPKDNTMSTTISLREYAEI------DASGGPIDGHIALKEY----- 743
            |....:.:.|...|...|....|||......|:..|::      ..|...:..:.:|:.|
  Rat   920 LHHLQIHLGAGSDSHEQDSTADDNTALLRFHLKYEADVLFTRSSSLSHFEVKANSSLESYDGIGP 984

  Fly   744 PYSA--EVNNSYEFKSHGPSIIDELTVYVDVPIAYTVTGSAGIKSIFNISSLQMQATHGSELVPI 806
            |::.  :|.|...|..||      :.:.:.||||                     ...|:.|:.:
  Rat   985 PFNCVFKVQNLGFFPIHG------VMMKITVPIA---------------------TRGGNRLLML 1022

  Fly   807 KLY--DQTNTL------AKEY---PLEDSSRRANRKRRELQQDQYAIMPDVNISDILTKENLPAN 860
            |.:  ||.||.      :.||   |.|:....| .:|.....|..:|:.:|.::        |..
  Rat  1023 KDFFTDQVNTSCNIWGNSTEYRSTPTEEDLSHA-PQRNHSNSDVVSIICNVRLA--------PNQ 1078

  Fly   861 RTLVLDCLRGN-WTICVRSQMRVQLKPEQPIDLRISFKVDLN-----DFVNTFDYLVIFTNVEMF 919
            .|...  |.|| |.:.:::     ||..       |.|:.:|     .|.:.|          :|
  Rat  1079 ETSFY--LVGNLWLMSLKA-----LKYR-------SMKITVNAALQRQFHSPF----------IF 1119

  Fly   920 KEGDSTSIALKRNLKPNVIFNYS---ETPLPIWYIILSLIAGHLLLGAMTYILYKLRFFKRGKKE 981
            :|.|.:.         .|.|..|   :..:|||.|:.|.:.|.|||..:...|:||.|||..|::
  Rat  1120 REEDPSR---------QVTFEISKQEDWQVPIWIIVGSSLGGLLLLALLVLALWKLGFFKSAKRK 1175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	FG-GAP	294..332	CDD:460357	13/38 (34%)
		Int_alpha	351..403	CDD:214549	23/53 (43%)
		Int_alpha	417..463	CDD:214549	19/45 (42%)
		Integrin_alpha2	453..837	CDD:462478	100/488 (20%)
Itga11	NP_001400722.1	Int_alpha	37..86	CDD:214549	19/70 (27%)
		vWA_integrins_alpha_subunit	163..341	CDD:238746	18/177 (10%)
		Int_alpha	476..523	CDD:214549	16/47 (34%)
		Int_alpha	538..592	CDD:214549	23/53 (43%)
		Integrin_alpha2	636..1064	CDD:462478	100/490 (20%)