Protein Alignment ItgaPS5 and Itga5

DIOPT Version :10

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: XP_063119754.1
• Gene: Itga5 / 315346
• RGDID: 2925
• Length: 1154
• Species: Rattus norvegicus
• Alignment Length: 1101
• Identity: 270/1101 - (24%)
• Similarity: 431/1101 - (39%)
• Gaps: 240/1101 - (21%)

  Fly     5 LFLIFLALKYQSNAMNFSPLPNRVIDAPKHLKTRMIQVRSSYFGYSL-VIRP----TSIFVGAPR 64
            |.|:......|....|.......|:..|.          .|.||:|: ..||    .|:.||||:
  Rat    80 LLLLLWPPPLQVGGFNLDAEAPAVLSGPP----------GSLFGFSVEFYRPGRDGVSVLVGAPK 134

  Fly    65 AQSTLESQGSINETGAVYRCPLASG--SCSHYVLNDKLN---------------KQFQWLGGSMD 112
            |.:   ||..:.:.||||.||..:.  .||....:.|.:               |..||.|.::
  Rat   135 ANT---SQPGVLQGGAVYVCPWGTSPIQCSTIQFDSKGSRILESSLYSEEPVEYKSLQWFGATV- 195

  Fly   113 GGTKDTDKLLVCAPRFFVPKNKN-YGQMRGICYWVRDTVADTPPLSDVRTISLIP------SQAE 170
              ......:|.|||.:.....|: .....|.||...:..        .|.:...|      |.|.
  Rat   196 --RAHGSSILACAPLYSWRTEKDPQNDPVGTCYLSTENF--------TRILEYAPCRSDFGSAAG 250

  Fly   171 EHFMLELGLSAHVTDDNSGFLIGAPGVRSWKGSVLVHRGEDLA-----------AQGSYAVKMLD 224
            :.: .:.|.||..| .....::|.||...|:|.:|....|.::           .||....:...
  Rat   251 QGY-CQGGFSAEFT-KTGRVVLGGPGSYFWQGQILSATQEQISESYYPQYLINPVQGQLQTRQAS 313

  Fly   225 S-WDWVKNHFTYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGKAYIFDVVGEIVRKLHVFHGE 288
            | :|     .:|:||:::.|.||.::...  :|...|...|..|  |:..:.|..:..|:...||
  Rat   314 SVYD-----DSYLGYSVAVGEFSGDDTED--FVAGVPKGNLTYG--YVTVLNGSDIHSLYNVSGE 369

  Fly   289 QLGEYFGYSVVAEDLNGDGLTDVVVSAPL----NALGDSYDVGAIYVFIN--KGLFKFEKKIIRL 347
            |:..||||:|.|.|.|||||.|::|.|||    .|.|...:||.:|:::.  :|:    :....|
  Rat   370 QMASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGRPQEVGRVYIYLQHPEGI----EPTPSL 430

  Fly   348 PLSSG---ARFGSSLSKVGDINHDGYNDLAVGAPFAG---NGAVFIFLGSEHGLRDEPSQRLD-- 404
            .|:..   .||||||:.:||::.|||||:|:||||.|   .|.||||.|...||..:|||.|.
  Rat   431 TLTGQDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGEAQQGVVFIFPGGPGGLNTKPSQVLQPL 495

  Fly   405 -APSREPGPYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEAVYLYRAYPVVKIHATVRSESRAI 468
             |....|     ..||..|..|.|:||||:.||.:|:.|.:...:||..|::...|::.......
  Rat   496 WAAGHTP-----DFFGSALRGGRDLDGNGYPDLIVGSFGVDKALVYRGRPIISASASLTIFPSMF 555

  Fly   469 RPEQETITV----TACYRLETTSKAR-QMQQQELTFRMTIDEL--------LQRVSF--APMRTN 518
            .||:.:.::    .:|..|.....|. :.....:.|.:.: :|        ::|..|  :...|.
  Rat   556 NPEERSCSLEGNPVSCINLSFCLNASGKHVPNSIGFEVEL-QLDWQKQKGGVRRALFLASKQATL 619

  Fly   519 EVSFQAQAGLSGSCRNFSVGVHYTGGI---FTPIDLELHYELAKKIP-HSHEA-----FCESCAV 574
            ..:...|.|....||...:.:......   .:||.:.|::.|..|.| .||..     :.....:
  Rat   620 TQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPKAPMDSHGLRPVLHYQSKSRI 684

  Fly   575 VDPLEPKYATGTLSFMTGCAA-HVCVSDLQLSSKDVNSSFIFGSLEVLSFSYEITNSGE-PAYVA 637
            .|..:         .:..|.. ::||.||||:..........|....|:.::...|.|| .||.|
  Rat   685 EDKAQ---------ILLDCGEDNICVPDLQLAVYGEKKHVYLGDKNALNLTFLAQNLGEGGAYEA 740

  Fly   638 QFNVTSSARLPFA---KVPGN-----CRV----RHEVMLCDLNGGRALARGDSESLTIIFDVTQL 690
            :..||:.....::   :.|||     |..    :...::|||  |..:..|.|....:.|.|..|
  Rat   741 ELRVTAPLEAEYSGLVRHPGNFSSLSCDYFAVNQSRQLVCDL--GNPMKAGTSIWGGLRFTVPHL 803

  Fly   691 SGQSLTI--EAAVSSAGMDQNPKDNTMSTTISLREYAEIDASG--------------GPIDGHIA 739
            .....||  :..:.|..:: |.:.|.:|..:|:...|::..:|              .|.|.  .
  Rat   804 QDTKKTIQFDFQILSKNLN-NSQSNMVSFPLSVEAQAQVSLNGVSKPEAVIFPVSDWNPQDQ--P 865

  Fly   740 LKEYPYSAEVNNSYEFKSHGPSIIDELTVYVDVPIAYTVTGSAGIKSIFNISSLQMQATHGSELV 804
            .||......|::.||..:.|||.|.:..:.:..|                      ||..|.:|:
  Rat   866 QKEGDLGPAVHHVYELINQGPSSISQGVLEISCP----------------------QALEGQQLL 908

  Fly   805 PIKLYDQTNTLAKEYPLEDSSRRANRKRRELQQDQYAIMPDVNISDILTKE----NLPANRTLVL 865
            .:......|.....|       ..|.:..||.       |:|:...:..:|    :...:.|.||
  Rat   909 YVTKVTGLNNCTSNY-------TPNSQGLELD-------PEVSPHHLQRREAPGRSSTTSGTQVL 959

  Fly   866 DCLRGNWTICVRSQMRVQLKP---EQPIDLRISFKVDLNDFVNTFDYLVIFTNVEMFKEGDSTSI 927
            .|....   |.|  :|.:..|   ::...|::.|:|....|:.. :|.......|...|
  Rat   960 KCPEAK---CFR--LRCEFGPLHRQESRSLQLHFRVWAKTFLQQ-EYQPFSLQCEALYE------ 1012

  Fly   928 ALK------------RNLKPNVIFNYSETP----LPIWYIILSLIAGHLLLGAMTYILYKL 972
            |||            :.|:......:::..    :|:|.|||:::.|.||||.:.|:|||:
  Rat  1013 ALKMPYQILPRQLPQKKLQVATAVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKV 1073

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	FG-GAP	294..332	CDD:460357	21/41 (51%)
		Int_alpha	351..403	CDD:214549	30/57 (53%)
		Int_alpha	417..463	CDD:214549	17/45 (38%)
		Integrin_alpha2	453..837	CDD:462478	85/437 (19%)
Itga5	XP_063119754.1	None