Protein Alignment ItgaPS5 and Itgam

DIOPT Version :9

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: XP_006230276.1
• Gene: Itgam / 25021
• RGDID: 2926
• Length: 1152
• Species: Rattus norvegicus
• Alignment Length: 1165
• Identity: 250/1165 - (21%)
• Similarity: 418/1165 - (35%)
• Gaps: 381/1165 - (32%)

  Fly    47 FGYSLVIRPTSI---FVGAPRAQS----TLESQGSIN-------------------ETGAVYRCP 85
            ||.:|:.:|...   ..|.|:.:|    .::..||||                   ::..::...
  Rat   126 FGSNLLRKPQQFPEALRGCPQQESDIAFLIDGSGSINSIDFQKMKEFVSTVMDQFQKSKTLFSLM 190

  Fly    86 LASGSC-SHYVLND---------------KLN--------------KQFQWLGGSMDGGTKDTDK 120
            ..|... :|:..||               :||              :.||.:.|:.|...    |
  Rat   191 QYSDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQKINGARDNAA----K 251

  Fly   121 LLVC---APRFFVPKNKN----YGQMRGICYWV---------------RDTVADTP------PLS 157
            :||.   ..:|..|.|..    ..:..||..:|               .||:|..|      .:.
  Rat   252 ILVVITDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRRELDTIASKPAGDHVFQVD 316

  Fly   158 DVRTISLIPSQAE-----------------EHFMLELGLSAHVTDDNSGFLIGAPGVRSWKGSVL 205
            :...::.|.:|.:                 ||.|.:.|.||.:|  ::|.|:|:.|...|.|...
  Rat   317 NFEALNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAIT--SNGPLLGSVGSFDWAGGAF 379

  Fly   206 VHRGEDLAAQGSYAVKMLDSWDWVKNHFTYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGKAY 270
            ::..:|.|.  ......:||    ..:..|:|||  |...|.|...||  |..||.
  Rat   380 LYPSKDKAT--FINTTRIDS----DMNDAYLGYA--SAVISRNRVQSL--VLGAPR--------- 425

  Fly   271 IFDVVGEIVRKLHVF---------HGEQLGEYFGYSVVAEDLNGDGLTDVVVSAPLNALGDSYDV 326
             :..:|.:|.....|         .|.|:|.|||.|:.:.|::.||.|::::            :
  Rat   426 -YQHIGLVVMFKQNFGAWEPHTDIKGSQIGSYFGASLCSVDMDADGNTNLIL------------I 477

  Fly   327 GAIYVFINKGLFKFEK----KIIRLPLSSG-------------------ARFGSSLSKVGDINHD 368
            ||.:        .:||    ::...||..|                   .|||::|:.:||:|.|
  Rat   478 GAPH--------HYEKTRGGQVSVCPLPRGQRARWQCEAILHGDQGHPWGRFGAALTVLGDVNGD 534

  Fly   369 GYNDLAVGAP--FAGNGAVFIFLGSEHGLRDEP-SQRLDAPSREPGPYGAHMFGQGLSRGSDIDG 430
            ...|:|:|||  ....|||:||.|:.......| |||:......|   |...|||.||.|.|:..
  Rat   535 KLTDVAIGAPGEQENQGAVYIFHGASVASISTPHSQRIAGARFSP---GLQYFGQSLSGGKDLTM 596

  Fly   431 NGFNDLAIGAPGAEAVYLYRAYPVVKIHATV----RSESRAIRPEQETIT-------VTACYRLE 484
            :|..|||:||.|  .:.|.||.||:::.||:    ::.:|::...||.:.       |..|..:.
  Rat   597 DGLMDLAVGAQG--RLLLIRAQPVLRLEATMEFSPKNLARSVFACQEEVVKNKDAGEVRVCLHVR 659

  Fly   485 TTSKARQMQ---QQELTFRMTID--ELLQRVSFAPMRTNEVSFQAQAGLSGSCRNFSVGV-HYTG 543
            ..:|.|..:   |..:|:.:.:|  ..:.|..|...:...:......||:..|....:.: ....
  Rat   660 KNTKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIRVFGLTQKCETLKLILPDCVD 724

  Fly   544 GIFTPIDLELHYELAKKIPHSHEAFCESCAVVDPLEPKYA-------TGTLSFMTGCAAH-VCVS 600
            ...:||.|.|:|.|..:...|..          .|.|..|       |....|...|... :|..
  Rat   725 NSVSPIILRLNYTLVGEPLRSSR----------DLRPVLAMEAQRIFTAMFPFEKNCGNDTICQD 779

  Fly   601 DLQLSSKDVN-SSFIFGSLEVLSFSYEITNSGEPAYVAQ----------FNVTSSARLPFAKVPG 654
            ||.::...:. ::.:.|.......|..:.|.||.:|..:          :...|:::..|:|.|
  Rat   780 DLSITVSSIRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKVSASQNQFSKKP- 843

  Fly   655 NCRVRHE-----------VMLCDLNGGRALARGDSE-SLTIIFDVTQLS--GQSLTIEAAVSSAG 705
             .||..|           ..:.|:|  ..:...:|| :..:.|||...:  |..|.::..|:|
  Rat   844 -WRVIAEPSSSEGQGVLKSTIWDIN--HPIFPANSEVTFNVTFDVDSDASLGNKLLLKVVVTS-- 903

  Fly   706 MDQNPKDNTMSTTISLREYAEIDASGGPI---------DGHIALKEYPYSAE------VNNSYEF 755
                  :|.:|.|.......|:     |:         .|..::|...::|.      :.:.|:|
  Rat   904 ------ENNVSRTDKTESQLEL-----PVKYAIYMVVTSGESSIKYLNFTASEMTSKVIQHQYQF 957

  Fly   756 KSHG------------PSIIDELTVYVDVPIAYTVTGSAGIKSIFNISSLQMQATHGSELVPIKL 808
            .:.|            |..|:::|:: |.|   .||.|..:.|:..
  Rat   958 NNLGQRSFPVSVVFWIPVQINKVTIW-DPP---QVTFSQNLSSVCR------------------- 999

  Fly   809 YDQTNTLAKEYPLEDSSRRANRKRRELQQDQYAIMPDVNISDILTKENLPANRTLVLDCLRGNWT 873
                        .|..|...::.:.||:                        ||.||:|   :..
  Rat  1000 ------------TEQKSPSHSKFQDELE------------------------RTPVLNC---SVA 1025

  Fly   874 ICVRSQMRVQLKPEQPIDLRISFKVDLND------FVNT-FDYLVIFTNVE-MFKE-------GD 923
            :|.|.|..:.....:.|     |.|.|..      ::.| .|:|::.:..| :|.:       |.
  Rat  1026 VCKRIQCDIPSFNSKEI-----FNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFALLPGQ 1085

  Fly   924 STSIALKRNLK--PNVIFNYSETPLPIWYIILSLIAGHLLLGAMTYILYKLRFFKRGKKE 981
            .|.:..:...|  |..:.|    |:|:  |:.|.:.|.:||..:|..||||.||||..|:
  Rat  1086 ETFVKAQTETKVEPYKVHN----PVPL--IVGSSVGGLVLLALITAGLYKLGFFKRQYKD 1139

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	VCBS	302..375	CDD:338792	20/95 (21%)
		Int_alpha	351..403	CDD:214549	23/73 (32%)
		Int_alpha	417..463	CDD:214549	21/49 (43%)
		Integrin_alpha2	451..836	CDD:337057	83/461 (18%)
Itgam	XP_006230276.1	vWA_integrins_alpha_subunit	149..324	CDD:238746	28/178 (16%)
		Int_alpha	453..510	CDD:214549	16/76 (21%)
		Int_alpha	517..570	CDD:214549	20/52 (38%)
		Int_alpha	582..>606	CDD:214549	11/23 (48%)
		Integrin_alpha2	615..1032	CDD:285619	91/505 (18%)
		Integrin_alpha	1129..1141	CDD:278771	7/11 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000