Protein Alignment ItgaPS5 and mew

DIOPT Version :10

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: XP_061514018.1
• Gene: mew / 1271955
• VectorBaseID: AGAMI1_006646
• Length: 1212
• Species: Anopheles gambiae
• Alignment Length: 1230
• Identity: 275/1230 - (22%)
• Similarity: 458/1230 - (37%)
• Gaps: 352/1230 - (28%)

  Fly    34 HLKTR-MIQVR---SSYFGYSLVIRPTSI-------------------FVGAPRAQSTLESQGSI 75
            :|:|| |::.:   .||||||:......:                   .||||..|:.   |...
Mosquito    26 NLETRHMLEKQGQPGSYFGYSVAGHSQRVGGGGGAGGRNGAGNATHWMLVGAPLGQNL---QPGS 87

  Fly    76 NETGAVYRCP--LASGSCSHYVL------------------------NDKL-------------- 100
            |.:||::|||  ||...|:..:.                        :|:|
Mosquito    88 NHSGALFRCPITLAQDDCTQVITDGHRSPTGKYLPFRQAYSKSDDFDDDELLGDGESRLEPPGVD 152

  Fly   101 -NKQFQWLGGSMDGGTKDTDKLLVCAPRFFV---PKNKNY------------GQMRGICYWVRDT 149
             .|..||||.:::.|.:: :|:.|||.|:..   |::..|            ||  |:||.:.:.
Mosquito   153 EIKNNQWLGVTVETGGQE-NKIFVCAHRYIKINNPQSLAYTASGPGSPGLYLGQ--GVCYVLNED 214

  Fly   150 VADTPPLSDVRTISLIPSQAEEHFMLELGLSAHVTDDNSGFLIGAPGVRSWKGSVLVHRGEDLAA 214
            .:....:...|..| |..:.:::...:.|.|..|..|.:. |||.||..:|||::.     ::|.
Mosquito   215 FSFGFAVEVCRGRS-IEREHQQYAFCQSGTSGAVLPDGTA-LIGTPGAMTWKGTLF-----NVAI 272

  Fly   215 QGSYAVKMLDSWDWVKNH---------FTYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGKAY 270
            :|.:..:  |.:.:...|         ::|:|.|::.|.|...   .:.|...||.:....|:..
Mosquito   273 EGGFLSR--DKFQYFAPHDNLHSPVPNYSYLGMAVTGGRFFGE---YMAYAGGAPRAAQGNGEVV 332

  Fly   271 I---------FDVVGEIVRKLHV--FHGEQLGEYFGYSVVAEDLNGDGLTDVVVSAPLNALGDSY 324
            |         ||         ||  ..|||.|..||.::.:.|:||||..|::|.||      :|
Mosquito   333 IFTNRQKRNPFD---------HVVSLRGEQFGSGFGSTLASADINGDGRLDLLVGAP------NY 382

  Fly   325 ----DVGAIYVFINKGLF---KFEKKII-RLPLSSGARFGSSLSKVGDINHDGYNDLAVGAPF-- 379
                |.||:||::|:|..   ::::::. ||.    :|||::::..||:||||.:|:|:|||:
Mosquito   383 FNRTDGGAVYVYLNRGTSFGPEYDQRLTGRLE----SRFGTAIANCGDLNHDGLDDVAIGAPYES 443

  Fly   380 AGNGAVFIFLGSEHG-LRDEPSQRLDAPSREPGPYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGA 443
            ||:|.|:|..|:..| |..||.|.:|.......|:  ..||..|..|.|:|||.:.||.||:..:
Mosquito   444 AGSGRVYIHFGTPDGALSPEPVQTIDPSELFATPW--RTFGSSLDGGHDLDGNSYPDLIIGSYAS 506

  Fly   444 EAVYLYRAYPVVKIHATVRSE---------SRAIRPEQETITVT-----ACYRLE--TTSKARQM 492
            :.|....|.|::.|......:         :|...|...|..||     ||..::  :.|:....
Mosquito   507 DRVVALLARPIINIRTYEEQQAGEPGSIDPTRVGCPSDPTANVTCFSFRACSAVDDASLSEGDVS 571

  Fly   493 QQQELTFRMTID-----ELLQRVSF-----------------APMRTNEVSFQAQAGLSGS--CR 533
            ....|..|.||.     ....||.|                 |..|||.:..:.:..:||.  |.
Mosquito   572 ADSSLQLRCTIQAETFLNKFSRVYFGTGGGPGADKTPAVPGAAATRTNILKRRFRLAVSGRPVCH 636

  Fly   534 NFSVGV-HYTGGIFTPIDLELHYEL------------------AKKIPHSHEAFCESCAVVDPLE 579
            :.:..: ..|..|..||...:.|.|                  .:::|.           ::|:.
Mosquito   637 DVTAYLKEGTRDIQNPIQFRISYTLDEERANGGTGAGGRRGRKERELPR-----------LEPIL 690

  Fly   580 PKYA---TGTLSFMTGCAAH-VCVSDLQLSSKDV------------NSSFIFGSLEVLSFSYEIT 628
            .:.|   |.|:.|...|... :|.|.|.:.:..:            ....:.|....|:.:..:.
Mosquito   691 NRTAAERTYTMPFQKDCGVDGLCQSALVIQNATLVGLARSGGAAGGEYQLVLGLDRTLTLALTVQ 755

  Fly   629 NSGEPAYVAQFNVTSSARLPFAKVPGN--CRVRHEVMLCDLNGGRALARGDSESLTIIFDVTQLS 691
            |..:.||.....|...|.|.:|...|:  |.. |...:.|.:.|..|.|.....|::.||...|.
Mosquito   756 NRADSAYETHLYVRHDASLTYAGSKGSSVCGA-HNATMVDCSIGNPLKRNGEVQLSLRFDARSLE 819

  Fly   692 -----------GQSLTIEAAVSSAGMDQNPK---------DNTMSTTIS---LREYAEIDASGGP 733
                       .|.:.:...|::...|...:         ...:..:||   |.|.......|..
Mosquito   820 EYGSSKGPNGLSQHVALAVFVNTTSQDTGNRTRAQLNLRIQRAVKLSISGKALPEQVFYGGGGEQ 884

  Fly   734 IDGHIALKEY-PYSAEVNNSYEFKSHGPSIIDELTVYVDVPI----------------AYTVTGS 781
            |.|..|:... .....|.:.|:..:.||.....:.:.:|.|:                |..|...
Mosquito   885 IMGESAIHSLDEIGMPVQHKYQIYNDGPWRAPMVRLEIDWPLQVANNKPQGKWLLYLDALPVLDM 949

  Fly   782 AGI----KSIFNISSLQMQATHGSELV---------PIKLYDQTNTLAKEYPL----EDSSRRAN 829
            :||    :|..::  |:.....|:.:.         |:.|..:|...|...|.    ..:..||.
Mosquito   950 SGIMGDGRSTCDV--LRKDEPDGAVVAGGDSVPLVNPLGLPSRTGPSAPPSPFTALRSANYTRAG 1012

  Fly   830 RKRRELQQDQYAIMPDVNISDILTKENLPANRTLVLDCLRGNWTI----------CVRSQMRV-Q 883
            |.||:                          |.:||....|:..:          |||...:: .
Mosquito  1013 RVRRD--------------------------RAMVLRPQAGDGAVQMDCASQTAKCVRIVCKIHD 1051

  Fly   884 LKPEQ----PIDLRISFKVDLNDFVNTFDYLVIFTNVEMFKEG---------DSTSIALKRNLKP 935
            |.|:.    .:..|:.....::|:... |.:.|.::.....||         ...|:.::....|
Mosquito  1052 LGPKSHALVTVTARLWNATLVSDYAQV-DVVRIGSSARFVVEGIDELLDQAHQPASLTVRTEAFP 1115

  Fly   936 NVIFNYSETPLPIWYIILSLIAGHLLLGAMTYILYKLRFFKR----GKKEELKRLLEEHR 991
            .:........:|.|.|:::.|.|.|:|.|:||:||:..||:|    |....|...||..|
Mosquito  1116 EMGPPIVAMDVPWWLILIAAITGLLVLIALTYLLYRCGFFRRKRHTGDDPTLSGNLERRR 1175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	FG-GAP	294..332	CDD:460357	16/41 (39%)
		Int_alpha	351..403	CDD:214549	25/54 (46%)
		Int_alpha	417..463	CDD:214549	16/45 (36%)
		Integrin_alpha2	453..837	CDD:462478	94/517 (18%)
mew	XP_061514018.1	None