Protein Alignment ItgaPS5 and LOC1270237

DIOPT Version :10

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: XP_308917.4
• Gene: LOC1270237 / 1270237
• VectorBaseID: AGAMI1_010351
• Length: 1124
• Species: Anopheles gambiae
• Alignment Length: 1163
• Identity: 359/1163 - (30%)
• Similarity: 556/1163 - (47%)
• Gaps: 202/1163 - (17%)

  Fly     7 LIFLALKYQS--NAMNFSPLPNRVIDAPKHLKTRMIQVRSSYFGYSLVIRPTSIFVGAPRAQSTL 69
            :|.:.|.|.|  :..|.||:.|.|...|. |||.:...||||||:|:.:|.:.:.||||:|||.|
Mosquito     2 IIPVLLTYLSTVDGFNLSPVANYVFTQPA-LKTFIRPTRSSYFGFSVNLRTSGVLVGAPQAQSDL 65

  Fly    70 ESQGSINETGAVYRCPLASGS-CSHYVLNDKLN-----------------KQFQWLGGSMDGGTK 116
            |.|.:||||||:|:|.....: |..|.|:.:.|                 |:.|.||.::||...
Mosquito    66 EYQRNINETGAIYKCSFEKPTECVPYRLDRQGNTNYEDYYTNHPEIRSELKEHQMLGATVDGLGS 130

  Fly   117 DTDKLLVCAPRFFVPKNKNYGQMRGICYWVRDTVADTPPLSDVRTISLIPSQAEE-------HFM 174
            |....:.|||:........| .:.|:||......|...| :::..|..:..:|::       ::|
Mosquito   131 DGAWFVACAPQLKGNTEIAY-LLHGVCYLTEGVEATEEP-NNLFKIKPLRGKAQQRRYGKSYNYM 193

  Fly   175 L-ELGLSAHVTDDNSGFLIGAPGVRSWKGSVLVHR-------GEDLAAQGSY-----AVKMLDSW 226
            . |.|.|.|||||....|||||||..|:|:||.:.       |.|.|::.:.     ..:.|...
Mosquito   194 YGEQGFSLHVTDDGDEVLIGAPGVMDWRGTVLRYHQRAAAIPGNDPASRSNVHQEYNRRRRLTHE 258

  Fly   227 DWVKNHF-------TYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGKAYIFD------VVGEI 278
            ..|.|..       :|.|||:|||.|..|::  :|||.:||.:....|:..|||      |...:
Mosquito   259 CVVPNPIHTNVPVNSYFGYAVSSGRFLGNHK--VLYVASAPQARSQHGEVIIFDYADNRTVWETV 321

  Fly   279 VRKLHVFHGEQLGEYFGYSVVAEDLNGDGLTDVVVSAPLNALGDSYDVGAIYVFINKGLFKFEKK 343
            :.:...|.|:|.||||||:::.||.|.|||.|:.:.||:::....:|.|.:|||:|.|...||
Mosquito   322 IVRYRTFVGQQFGEYFGYALLTEDFNSDGLPDLAIGAPMHSRAREHDNGVVYVFLNAGELNFE-- 384

  Fly   344 IIRLPLSS----GARFGSSLSKVGDINHDGYNDLAVGAPFAGNGAVFIFLGSEHGLRDEPSQR-- 402
             ::..|:|    |.|||:||.|:||:|.|||.|:|:||||...|||:|||||.:|:...||||
Mosquito   385 -LQSKLASSYELGGRFGTSLGKIGDLNRDGYGDIAIGAPFEEAGAVYIFLGSANGVPSRPSQRLV 448

  Fly   403 -----LDAPSREPGPYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEAVYLYRAYPVVKIHATVR 462
                 |..|||.|     :|||..|:||.||||||:.|||:|||..||||::|:||:|:|.|.:.
Mosquito   449 PSAAHLRTPSRHP-----YMFGHALTRGIDIDGNGYTDLAVGAPNGEAVYVFRSYPIVRIEARIN 508

  Fly   463 SESRAIRPEQETITVTACYRLETTSKARQMQQQELTFRMTIDELLQRVSFAPMRTNEVSFQAQAG 527
            |..|.:..|.....:..|:  .|...|.......|.:.:.:|..:.|.|.....:.|...:: ..
Mosquito   509 STKRELPEEGGVFEIAVCW--STEYPAGVAFPVALQYTLDVDGQMGRASVGNRSSPEAPHES-VT 570

  Fly   528 LSGS--CRNFSVGVHYT-GGIFTPIDLELHYEL-AKKIPHSHEAFCESCAVVDPLEPKYATGTLS 588
            :||.  ||.:|:.|:.: ..::.||.:|:.:.: |...|.....||:.||::||....:....:.
Mosquito   571 VSGDPLCRQYSITVNASPTTLYKPIAIEVEFGMAATATPPKGGPFCDRCAILDPDVSSHVQERIP 635

  Fly   589 FMTGCAAHVCVSDLQLSS---KDVNSSFIFGSLEVLSFSYEITNSGEPAYVAQFNVT-----SSA 645
            |.|||...||.:||::::   .|:...|:.||.:.::...||.|:||.||:.|.||:     .|.
Mosquito   636 FKTGCRKEVCETDLKITNIRWVDIVPPFVVGSAKKVTLEVEIENAGENAYLPQLNVSVPSFLRSV 700

  Fly   646 RLPFAKVPGNC----RVRHEV-MLCDLNGG---RALARGDSESLTIIFDVTQLSGQS--LTIEAA 700
            ..|    |..|    .||.|: :||.||.|   :|..| ...|||:  ||||:...:  |.:...
Mosquito   701 HPP----PSECAQSGAVRGEISILCGLNNGLPLKAFTR-MKHSLTL--DVTQVQPGTAFLELRLK 758

  Fly   701 VSSAGMDQNPKDNTMSTTISLREYAEIDASGGPIDGHIALKEYPYSAE-------VNNSYEFKSH 758
            |.:...:|.|:||.:...:.|||::.||         |..|..|..|.       :|.|...|.|
Mosquito   759 VLTTSKEQWPRDNEVEERLLLREFSHID---------IVSKTTPREANFETLTGFLNVSQLVKLH 814

  Fly   759 --GPSIIDELTVYVDVPIAYTVTGSAG-------------IKSIFNISSLQ---MQATHGSEL-- 803
              |||.:.......|:|::||.|...|             ::|.:|.:.|:   :||..|..|
Mosquito   815 NNGPSTLSGALFLADIPLSYTPTHLGGHKSCPVVRLEDITVRSSYNETPLEVDWIQAAGGKGLLK 879

  Fly   804 -------------------------------VPI-----KLYDQTNTLAKEYPLEDSSRRANRKR 832
                                           ||.     :|.|:.:..|  :.|..::..|.:||
Mosquito   880 QTFAFYSKKQPEPYYPAREEDDVPSNFEFTVVPYNGHEPELLDEKHPYA--HALVGNADSARQKR 942

  Fly   833 RELQQDQYAIMPDVNISDILTKENLPANRTLVLDCLRGNWTI-CVRSQMRVQLKP----EQPIDL 892
            ..|    :...|....|..:..:.||..||:..:|.:....: |:  |:::.|.|    .:||.:
Mosquito   943 SNL----WLAPPTRPSSASIQLDELPTLRTVHFNCAQNLSDVECL--QLQIWLPPFPVANKPIYV 1001

  Fly   893 RISFKVDLNDFVNTF----DYLVIFTNVEMFKEGD--STSIALKRNLKPNVIFNYSETPLPIWYI 951
            .:.::::||......    |..|:....::.|..|  ..:..:.||....|::.......|||..
Mosquito  1002 ELQYRLNLNAIAACMREQEDIFVVQVLTDLVKPLDERKETFRIARNHPYTVVYRDVSVSTPIWIY 1066

  Fly   952 ILSLIAGHLLLGAMTYILYKLRFFKRGKKEELKRLLEEHRSETKEPATDCEGNQEEIN 1009
            :.|...|.|||.|:||.::::.||:|..::|::::..|  |...:..||.|...:|::
Mosquito  1067 VTSSFGGLLLLAAITYTMHRVGFFERHMRQEMEKMNRE--SGILDSTTDPEETAQEVS 1122

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	FG-GAP	294..332	CDD:460357	15/37 (41%)
		Int_alpha	351..403	CDD:214549	33/62 (53%)
		Int_alpha	417..463	CDD:214549	28/45 (62%)
		Integrin_alpha2	453..837	CDD:462478	120/468 (26%)
LOC1270237	XP_308917.4	None