Protein Alignment ItgaPS5 and Itga6

DIOPT Version :9

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: XP_038960023.1
• Gene: Itga6 / 114517
• RGDID: 621633
• Length: 1090
• Species: Rattus norvegicus
• Alignment Length: 1192
• Identity: 287/1192 - (24%)
• Similarity: 461/1192 - (38%)
• Gaps: 307/1192 - (25%)

  Fly     4 LLFLIFLALKYQSNAMNFSPLPNRVIDAPKHLKTRMIQVRSSYFGYSLV----IRPTS---IFVG 61
            ||:|....|...|.|.|.....:.||        |......|.||:||.    ::|..   :.||
  Rat     9 LLYLSAGLLARLSTAFNLDTREDNVI--------RKSGDPGSLFGFSLAMHWQLQPEDKRLLLVG 65

  Fly    62 APRAQSTLESQGSINETGAVYRCPLAS-GSCSHYVLNDKL-----NKQFQWLGGSMD----GGTK 116
            ||||:: |..| ..|.||.:|.|.:.| |.|:..|.::..     :|:.||:|.::.    ||
  Rat    66 APRAEA-LPLQ-KANRTGGLYSCDITSRGPCTRIVFDNDADPMSESKEDQWMGVTVQSQGPGG-- 126

  Fly   117 DTDKLLVCAPRFFVPKNKNYGQ----MRGICYWVRDTVADTPPLS-------DVRTISLIPSQAE 170
               |::.||.|:...::.|..|    :.|.||.:...:.....:.       |.|.      :..
  Rat   127 ---KVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRL------RGH 182

  Fly   171 EHF-MLELGLSAHVTDDNSGFLIGAPGVRSWKGSVLVHRGE------DLAAQGSYAVKMLDSWDW 228
            |.| ..:.|::|..|.|....:.||||..:|||.|.|.:..      ::...|.|.|      ..
  Rat   183 EKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEV------GG 241

  Fly   229 VKNH---------FTYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGKAYIF---DVVGEIVRK 281
            ..:|         .:|:|::|.||. ...::..:.:|:.||.:  |...|.:.   |:....:..
  Rat   242 ETDHDESLVPVPANSYLGFSLDSGK-GIVSKDDITFVSGAPRA--NHSGAVVLLKRDMKSAHLLL 303

  Fly   282 LHVFHGEQLGEYFGYSVVAEDLNGDGLTDVVVSAPLNALGDSYDVGAIYVFINKGLFKFEKKIIR 346
            .::|.||.|...|||.|...|||.||..|:|:.||.....|....||:||:||:.......|.:|
  Rat   304 EYIFDGEGLASSFGYDVAVVDLNADGWQDIVIGAPQYFDRDGEVGGAVYVYINQQGRWSNVKPVR 368

  Fly   347 LPLSSGARFGSSLSKVGDINHDGYNDLAVGAPFAGNGAVFIFLGSEHGLRDEPSQRLDAPSREPG 411
            |..:..:.||.::..:||||.|||.|:|||||:...|.|||:.||..|:..:|:|.|:..:
  Rat   369 LNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSPTGIITKPTQVLEGTT---- 429

  Fly   412 PYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEAVYLYRAYPVVKIHATV---------RSESRA 467
            |:    ||..::...|:|.|.:.|:|:|:. :::|.::|:.||:.|..|:         |.:|..
  Rat   430 PF----FGYSIAGNMDLDRNSYPDVAVGSL-SDSVTIFRSRPVINILKTITVTPSRIDLRQKSMC 489

  Fly   468 IRPEQETITVTACYR-----------------LETTSKAR------------QMQQQELTFRMTI 503
            ..|....:.|.||:.                 ||...:.|            |..:.:.|..:|:
  Rat   490 GSPSGICLKVKACFEYTAKPSGYNPPISILGILEAEKERRKSGLSSRVQFRNQGSEPKYTQELTL 554

  Fly   504 DELLQRVSFAPMRTNEVSFQAQAGLSGSCRNFSVGVHYTGGIFTPIDLELHYELAKKIPHSH--- 565
            :...||...      |.:...|..:....|              ||.:....|:.:  |.|.
  Rat   555 NRQKQRACM------EETLWLQENIRDKLR--------------PIPITASVEIQE--PSSRRRV 597

  Fly   566 EAFCESCAVVDPLEPKYATGTLSFM-TGCA-AHVCVSDLQLSSKDVNSSFIFGSLE--VLSFSY- 625
            .:..|...:::..|.|.....:.|: .||. .:||.|:|:|..|       ||:.|  ...|||
  Rat   598 NSLPEVLPILNSNEAKTVQTDVHFLKEGCGDDNVCNSNLKLEYK-------FGTREGNQDKFSYL 655

  Fly   626 -------------------EIT------------NSGEPAYVAQF------NVTSSARLPFAKVP 653
                               |||            ..|:.|:.|:.      .:|.||.......|
  Rat   656 PIQKGIPELVLKDQKDIALEITVTNGPSDPRNPRKDGDDAHEAKLIATFPDTLTYSAYRELRAFP 720

  Fly   654 G---NCRVRHEVMLCDLNGGRALARGDSESLTIIFDVTQLSGQSLTIEAAVSSAGMDQNPK---- 711
            .   :|.........|...|....|..|.:..:|...|         |....:..:|.|.|
  Rat   721 EKQLSCVANQNGSQADCELGNPFKRNSSVTFYLILSTT---------EVTFDTTDLDINLKLETT 776

  Fly   712 ---DNTMSTTISLREYAEIDAS------------GGPIDGHIALKEYPYSAEVNN--SYEFKSHG 759
               ||....|...:...|:..|            ||.:.|..|:|.   ..||.:  .|||:
  Rat   777 SNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKS---EDEVGSLIEYEFR--- 835

  Fly   760 PSIIDELTVYVDVPIAYTVTGSAGI---KSIFN---ISSLQMQATHGSELVPIKLYDQTNTLAKE 818
                   .:.:..|:....|.:..|   |.|.|   :..|....:.|.|.|..:.:::.|.|
  Rat   836 -------VINLGKPLKNLGTATLNIQWPKEISNGKWLLYLMKVESKGLEQVVCEPHNEINFL--- 890

  Fly   819 YPLEDSSRRANRKRRELQQDQYAIMPDVNISDILTKENLPANRTLVLDCLRGNWTICVRSQMRVQ 883
             .|::|..  :||:|||        |:..|.|..........:...|:|     ::.||.   |.
  Rat   891 -KLKESHN--SRKKREL--------PEKQIDDSRKFSLFSERKYQTLNC-----SVNVRC---VN 936

  Fly   884 LK-PEQPIDLRISFKVDLNDFVNTF-------DYLVIFTNVEMFKEGDSTSIALKRNLK-PNVIF 939
            :: |.:.:|.:.|..:....:.:||       :||.|.....:    |.|:.|  :|:| |:...
  Rat   937 IRCPLRGLDSKASLVLRSRLWNSTFLEEYSKLNYLDILVRASI----DVTAAA--QNIKLPHAGT 995

  Fly   940 NYSETPLPI-----------WYIILSLIAGHLLLGAMTYILYKLRFFKRGKKEELKRLLEEHRSE 993
            ....|..|.           |.|:|:::||.|:|..:.::|:|..||||.:.::         |.
  Rat   996 QVRVTVFPSKTVAQYSGIAWWIILLAVLAGILMLALLVFLLWKCGFFKRSRYDD---------SV 1051

  Fly   994 TKEPATDCEGNQEEINVEMHSD 1015
            .:..|......:.|||.|.|:|
  Rat  1052 PRYHAVRIRKEEREINDEKHTD 1073

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	VCBS	302..375	CDD:338792	29/72 (40%)
		Int_alpha	351..403	CDD:214549	24/51 (47%)
		Int_alpha	417..463	CDD:214549	14/54 (26%)
		Integrin_alpha2	451..836	CDD:337057	98/497 (20%)
Itga6	XP_038960023.1	Int_alpha	40..100	CDD:214549	23/61 (38%)
		Int_alpha	254..>292	CDD:214549	10/40 (25%)
		Int_alpha	314..364	CDD:214549	20/49 (41%)
		Int_alpha	374..425	CDD:214549	24/50 (48%)
		Integrin_alpha2	464..939	CDD:400650	107/547 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335756
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840