Protein Alignment ItgaPS5 and itga6

DIOPT Version :9

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: XP_002934665.3
• Gene: itga6 / 100497992
• XenbaseID: XB-GENE-489982
• Length: 1095
• Species: Xenopus tropicalis
• Alignment Length: 1147
• Identity: 273/1147 - (23%)
• Similarity: 456/1147 - (39%)
• Gaps: 278/1147 - (24%)

  Fly    45 SYFGYSLVIR----PTS---IFVGAPRAQSTLESQGSINETGAVYRCPLA--SGSCSHYVLNDKL 100
            |.||:|:.:.    |.:   :.||:|||:: |.:| ..|.||.:|.|.:.  |.||:..:.:|.:
 Frog    38 SLFGFSMAMHWQLDPVNRRLLLVGSPRAKA-LPAQ-KANVTGGLYVCDITSPSPSCNRVLFDDSV 100

  Fly   101 -----NKQFQWLGGSMD----GGTKDTDKLLVCAPRF--FVPKNKNY--GQMRGICY-WVRD-TV 150
                 :|:.||:|.|:.    ||     |::.||.|:  ....|.||  ..:.|.|| :.:| |:
 Frog   101 DLTSESKENQWMGVSVQSQGPGG-----KIVTCAHRYERRTSVNTNYENRDITGRCYVFSQDLTM 160

  Fly   151 ADTPPLSDVRTISLIPSQAEEHFMLELGLSAHVTDDNSGFLIGAPGVRSWKGSVLVHRG----ED 211
            .|.....|...........|:....:.|::|..|.|....:.||||..:|||.|...:.    ||
 Frog   161 TDEMDGGDWNFCEGRRRGHEQFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGVVRAEQKNNTLED 225

  Fly   212 L--AAQGSYAV---KMLDSWDWV---KNHFTYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGK 268
            |  ...|.|..   ...|| |.|   .|  :|:|::|.:|. ...::..:.:|:.||.:  |...
 Frog   226 LFIFEDGPYETGGENKRDS-DLVPAPDN--SYLGFSLDTGR-GITSKEEMTFVSGAPRA--NHSG 284

  Fly   269 AYI----FDVVGEIVRKLHVFHGEQLGEYFGYSVVAEDLNGDGLTDVVVSAPLNALGDSYDV-GA 328
            |.:    |.....::..:|.|.||.|...|||.|...|||.||..|:||.||.....:..:: ||
 Frog   285 AVVLLQKFPPNERMLSAVHTFQGEGLASSFGYDVAVVDLNRDGWKDIVVGAPQYFDKNDREIGGA 349

  Fly   329 IYVFINKGLFKFEKKIIRLPLSSGARFGSSLSKVGDINHDGYNDLAVGAPF-AGNGAVFIFLGSE 392
            |||:||:.....:...:|:..:..:.||.|:..:||||.|||.|:|||||: .|.|.|:::.||:
 Frog   350 IYVYINQQGNWNDVMPVRIVGTKDSMFGISVKNIGDINQDGYPDIAVGAPYDDGFGKVYVYHGSK 414

  Fly   393 HGLRDEPSQRLDAPSREPGPYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEAVYLYRAYPVVKI 457
            .|:..||:|.::..|.     ....||..::...|:|.|.:.|:|:|:. :::|.::|:.||:.|
 Frog   415 DGIISEPAQVIEGRST-----NTRFFGYSIAGDMDLDQNSYPDIAVGSL-SDSVKVFRSRPVITI 473

  Fly   458 HATVR--------SESRAIRPEQETITVTACYRLETTSKA-RQMQQQELTFRMTID-ELLQRVSF 512
            ..|::        ::.....|....:.|..|:......|. ..:.....||.:..| .|||:
 Frog   474 KKTIKVTPDRIDFNKKNCDAPSGICLEVEGCFEYTANPKTYNPVLTLSCTFELENDRRLLQK--- 535

  Fly   513 APMRTNEVSFQAQAGLSGSC----RNFSVGVHYTGGIFTPIDLELH---------YELAKKIPHS 564
             |:|.|......::.|..:.    :|....|..|..:...|..:||         .:..::....
 Frog   536 -PLRMNFKDLPQESKLPKTIELRGQNQRRCVTTTLQLLESIRDKLHPIAVSVSAEIKSVRRRKRQ 599

  Fly   565 HEAFCESCAVVDPLEPKYATGTLSFM-TGCAA-HVCVSDLQLSSKDV-----NSSFI----FGSL 618
            .....|...:::..|||.||..:.|: .||.. ::|.|::||..|.:     :.||.    ...:
 Frog   600 SSPLPELMPILNSNEPKNATANVQFLKEGCGEDNICNSNMQLKYKFLTREGSHDSFTELKQENGI 664

  Fly   619 EVLSFSYE--------ITN----------SGEPAYVAQFNVTSSARLPFAKV---------PGNC 656
            .||:...:        :||          .|:.|:.||......:.|.::|.         |..|
 Frog   665 PVLALKNQKEIALEVTVTNKPSNPANPKLDGDDAHEAQLTAELPSSLSYSKYVELNPQLDKPLIC 729

  Fly   657 --RVRHEVMLCDLNGGRALARGDSESLTIIFDVTQLSGQSLTIEAAVSSAGMDQNPKD--NTMST 717
              .....|:.|:|  |....|..:.:..:|....::|              :|.|..|  ..:.|
 Frog   730 ASNPNGSVVFCEL--GNPFKRNANVTFYLILSTNEIS--------------VDTNELDIGLNLKT 778

  Fly   718 TISLREYAEIDAS----------------------GGPIDGHIALKEYPYSAEVNNSYEF----- 755
            |.|....|.:.|.                      ||.:.|..|:|.   ..::.|..:|
 Frog   779 TSSQANLAPVAAKARVVVELLLSVSGVAKPSQVYFGGNVLGESAMKS---EDDIGNLIDFDFRVT 840

  Fly   756 ------KSHGPSIIDELTVYVDVPIAYTVTGSAGIKSIFNISSL------------QMQATHGSE 802
                  |:.|.:.::     :..|           |.|:|...|            :|:.....|
 Frog   841 NFGRPLKALGTTFLN-----IQWP-----------KEIYNGKWLLYLVKMESEGLDKMECQPAGE 889

  Fly   803 LVPIKLYDQTNTLAKEYPLEDSSRRANRKRRELQQDQYAIMPDVNISDILTKENLPANRTLVLDC 867
            :..:||.:...|               |.|||:.:.|.. ..|.:.|  |..|    .:.:.|||
 Frog   890 INKLKLLESGKT---------------RHRREIGESQSG-TSDKSFS--LFSE----RKYMTLDC 932

  Fly   868 LRGNWTICVRSQMRVQLKPEQPIDLRISFKVDLNDFVNTF-------DYLVIFT----------- 914
              .|...||..:.     |...:|.....|.....:.:||       :||.|..
 Frog   933 --NNQAKCVTIKC-----PLHGMDSNAIIKARSRLWNSTFLEEYSKMNYLDILVKVFISVDTAAQ 990

  Fly   915 NVEMFKEGDSTSIALKRNLKPNVIFNYSETPLPIWYIILSLIAGHLLLGAMTYILYKLRFFKRGK 979
            |:::..||....:.:   .....:..||  .:|.|.|.::::||.|:|..:.::|:|..||||.:
 Frog   991 NIKLANEGYQVRVTV---FPEKTVAQYS--GVPWWIIFVAILAGILMLALLVFLLWKCGFFKRSR 1050

  Fly   980 KEE------LKRLLEEHR----------SETKEPATDCEGNQ 1005
            .::      ..|:.:|.|          ||.|:..|....|:
 Frog  1051 YDDSVPRYHAVRISKEEREYKDGKLPKNSEKKQWVTKWNENE 1092

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	VCBS	302..375	CDD:338792	29/73 (40%)
		Int_alpha	351..403	CDD:214549	25/52 (48%)
		Int_alpha	417..463	CDD:214549	14/53 (26%)
		Integrin_alpha2	451..836	CDD:337057	90/494 (18%)
itga6	XP_002934665.3	Int_alpha	36..97	CDD:214549	20/60 (33%)
		Int_alpha	251..300	CDD:214549	11/53 (21%)
		Int_alpha	312..361	CDD:214549	21/48 (44%)
		Int_alpha	373..425	CDD:214549	25/51 (49%)
		Int_alpha	434..>457	CDD:214549	7/22 (32%)
		Integrin_alpha2	467..943	CDD:369878	101/538 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910