Protein Alignment ItgaPS5 and itgav

DIOPT Version :9

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: NP_001028893.1
• Gene: itgav / 100151255
• ZFINID: ZDB-GENE-060616-382
• Length: 1045
• Species: Danio rerio
• Alignment Length: 1107
• Identity: 295/1107 - (26%)
• Similarity: 471/1107 - (42%)
• Gaps: 248/1107 - (22%)

  Fly    45 SYFGYSLV-IRPT----SIFVGAPRAQSTLESQGSINETGAVYRCP-LASGSCSHYVL---NDKL 100
            ||||:|:. ..|.    :|.||||||.::.::..::.|.|||:.|| ..||:|:....   :|:.
Zfish    41 SYFGFSVAFFNPDNSQFNILVGAPRANTSDQTPSAVTERGAVFSCPWQKSGTCTQIQFDSTDDRK 105

  Fly   101 N--------KQFQWLGGSMDGGTKDTDKLLVCAPRFFVPKNKNYG----QMRGICYWVR-DTVAD 152
            :        |..||.|.::   ....|::|.|||.:   :...||    :..|.||..: :.:.:
Zfish   106 HSNGQQMEFKSNQWFGATV---RSSGDQILACAPLY---QWSTYGFSEREPVGTCYLKKGNNIVE 164

  Fly   153 TPPLSDVRTISLIPSQAEEHFMLELGLSAHVTDDNSGFLIGAPGVRSWKGSVL-------VHR-G 209
            ..|   .|:.|..|   |.....:.|.||.....|. .:||.||...|:|.::       ::| .
Zfish   165 YSP---CRSKSNSP---EGQGFCQAGFSADFVKKNR-VVIGGPGSFYWQGQLISDDVTEVINRYN 222

  Fly   210 EDLAAQGSYAVKMLDSWDWVKNHFTYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGKAYIFDV 274
            :|...  .|:.::.......:...:|:||:::.|.|:.:....  |||..|......|...||:
Zfish   223 KDFLT--PYSNQLSTKPAGAQYDDSYLGYSVAVGDFNEDGEDD--YVTGVPRGEKALGYVNIFN- 282

  Fly   275 VGEIVRKLHVFHGEQLGEYFGYSVVAEDLNGDGLTDVVVSAPL----NALGDSYDVGAIYVFINK 335
             |..:..::.|.|.|:..|||:||.|.|:|.||..|:.|.|||    .:.|...:||.:||::.|
Zfish   283 -GRNMESMYNFTGTQMAAYFGHSVAAVDVNNDGKMDLFVGAPLFMDRGSDGKLREVGQVYVYLGK 346

  Fly   336 GLFKFEKKIIRLPLSS-GARFGSSLSKVGDINHDGYNDLAVGAPFAG---NGAVFIFLGSEHGLR 396
            |.|.| ..:|:|..|. .||:|||:..|||:|.|||||:|:.||:.|   .|.|:|..|...|..
Zfish   347 GGFTF-NSVIKLTGSEIYARYGSSVCSVGDLNMDGYNDVAIAAPYGGPFHRGLVYIHNGRSTGPN 410

  Fly   397 DEPSQRLDA-------PSREPGPYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEAVYLYRAYPV 454
            ...||.|:.       ||         .||..::.|:|:|.||:.||.:||.||:...||||.||
Zfish   411 PVASQVLEGTWASVSMPS---------SFGYSMNGGTDVDQNGYPDLIVGAFGADKAILYRARPV 466

  Fly   455 VKIHATVRSESRAIRPEQE------TITVTACYRLETTSKAR-QMQQQELTFR--MTIDEL---- 506
            :.::.|:....:.:.||.:      |.|..:|:.::...||. :.....|.|:  :|:|.|
Zfish   467 ISVNTTLDISPQILNPEDKSCTLPGTATKVSCFTVKYCLKASGKGAPSSLLFQVDLTLDRLKHKG 531

  Fly   507 -LQRVSFAPMRTNEVSFQAQAGLSGSCRNFSVGVHYTGGI------------------FTPIDLE 552
             ::||.|.   .|::|..::          ::.|:...|:                  .|||.:.
Zfish   532 AIKRVLFL---YNKMSHYSK----------NMTVNNNQGLACEELQAYLIDDSEFRDKITPISVF 583

  Fly   553 LHYELAKK--------IPHSHEAFCESCAVVDPLEPKYATGTLSFMTGCAA-HVCVSDLQLSSKD 608
            :.|.|..|        :|           ::|...|...|.....:..|.. ::|..||:||...
Zfish   584 MEYSLDYKSAADKTGLLP-----------ILDQSAPTNVTKQAHILLDCGEDNICKPDLKLSVVS 637

  Fly   609 VNSSFIFGSLEVLSFSYEITNSGEPAYVAQFNVTSSARLPFAKVPGN--------CRVRHE---- 661
            ..:....|....|:......|.||.||.|...||..::..|..|..|        |..:.:
Zfish   638 DQNEIYIGDDNPLTLEVTAENGGEGAYEADLIVTLPSQADFTAVVRNSETLSRLSCAFKKDNQTR 702

  Fly   662 VMLCDL----NGGRALARGDSESLTIIFDVTQLSGQSLTIEAAVSSAGMDQ-NPKDNTMSTTISL 721
            |::|||    .||..:..|      :.|.|.|||.|...::..:.....:| |...|.:|....|
Zfish   703 VVVCDLGNPMKGGTKIVAG------LRFSVHQLSEQDTEVKFGLQIQSTNQFNNTSNLVSVVTKL 761

  Fly   722 REYAEIDASGGPIDGHIAL-------KEYPYSAE-----VNNSYEFKSHGPSIIDELTVYVDVPI 774
            ...|:::..|......:.|       ||.|...:     |.:.||.::.|||...:..:.|..|.
Zfish   762 AVLAKVELRGVSAPEQVFLPIANWQPKENPVLEDDIGPLVQHIYELRNKGPSTFSKAILDVQWPY 826

  Fly   775 AYTVTGSAGIKSIFNISSLQMQATHGSELVPI-----KLYDQTNTLAKEYPLEDSSRRANRKRRE 834
            .:. .||....:.|::.. .|..:...||.|:     :..||.:|.|..   .:...|.|..||:
Zfish   827 RFN-NGSLLYITKFSVDG-NMNCSSNRELNPLNVTSPRFLDQNDTSASG---AEGRNRHNVHRRD 886

  Fly   835 LQQDQYAIMPDVNISDILTKENLPANRTLVLDCLRGNWTICVRSQMRV-QLKPEQPIDLRISFKV 898
            |::..             .:|||.     :|||  || ..|...:..| :|:..|...|.|..::
Zfish   887 LEEKH-------------GEENLE-----ILDC--GN-AECQEIKCFVGRLEKGQSAILFIYSRL 930

  Fly   899 DLNDFV----NTFDYLV----IFTNVEM-FKEGDSTSIALKRNLKP-----------NVIFNYSE 943
            .:|.|:    ....|:|    .|:.:|| :|           ||.|           .||:| ||
Zfish   931 AVNTFLKAESQNKSYIVRSSASFSVIEMPYK-----------NLNPELPTSTQSASLKVIWN-SE 983

  Fly   944 TPLPI--WYIILSLIAGHLLLGAMTYILYKLRFFKRGKKEELKRLLEEHRSETK--EPATDCEGN 1004
            .|.|:  |.:.|:::||.|||..:.:::|||.||.|      .|..:|.|:|.:  :|..:.:.|
Zfish   984 NPQPVPGWVVALAVLAGLLLLALLIFVMYKLGFFNR------VRPPQEDRTEKEQLQPQENGDRN 1042

  Fly  1005 QE 1006
            .|
Zfish  1043 TE 1044

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	VCBS	302..375	CDD:338792	35/77 (45%)
		Int_alpha	351..403	CDD:214549	25/55 (45%)
		Int_alpha	417..463	CDD:214549	20/45 (44%)
		Integrin_alpha2	451..836	CDD:337057	100/459 (22%)
itgav	NP_001028893.1	Int_alpha	39..99	CDD:214549	22/57 (39%)
		VCBS	255..320	CDD:290251	23/68 (34%)
		Int_alpha	297..>345	CDD:214549	20/47 (43%)
		Int_alpha	362..417	CDD:214549	25/54 (46%)
		Int_alpha	426..>470	CDD:214549	21/52 (40%)
		Integrin_alpha2	463..911	CDD:285619	110/503 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574887
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840