DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rrp4 and SPAC2F7.14c

DIOPT Version :9

Sequence 1:	NP_001286771.1	Gene:	Rrp4 / 37731	FlyBaseID:	FBgn0034879	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	NP_592984.1	Gene:	SPAC2F7.14c / 2541813	PomBaseID:	SPAC2F7.14c	Length:	329	Species:	Schizosaccharomyces pombe

Alignment Length:	274	Identity:	121/274 - (44%)
Similarity:	173/274 - (63%)	Gaps:	13/274 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DLALDRVDWRDLAAQTEE--QPRVYTPGEVLMPEAGFMRGHGTFVEDENIKSSVAGVIQKVNKLI 70
            |..:..||..|:..:.::  ...:.|||:::..:..|||||||:.||..|.:||||.:|:|||||
pombe    34 DEQMGLVDGEDVLEEFDKSIHQNLVTPGQLVTDDPQFMRGHGTYFEDGGIYASVAGSVQRVNKLI 98

  Fly    71 SVRPLKSRYVGEIGDVVVARVSEVQQKRWRVDTNSRLDSILLLSSVNLPGGELRRRSAEDEQMMR 135
            ||:||:|:||.||||:::.:::|||.|||:||..::.:::|:|||:|||||..||:...||..||
pombe    99 SVKPLRSKYVPEIGDLIIGKIAEVQPKRWKVDIGAKQNAVLMLSSINLPGGIQRRKLETDELQMR 163

  Fly   136 RYLDEGDLISAEVQNIFEEGSLSLYTRSLKYGKLSQGILVKVFPALVKRRKMHFHNLPCGASVIL 200
            .:..||||:.||||..|.:||:|::|||||||||..|:.:||.||||.|.|.|.:.|..|..:||
pombe   164 SFFQEGDLLVAEVQQYFSDGSVSIHTRSLKYGKLRNGVFLKVPPALVVRSKSHAYALAGGVDIIL 228

  Fly   201 GNNGYIWISP-TKGQ---------EEEGGEGGFAQNLNEHVPRADREVIARLRNSILALAKCKLM 255
            ..|||:|:|. .:.|         |||..|..:: |.|:.:....|..|:|:...|..||...|.
pombe   229 SVNGYVWVSKHNENQHSSVSITRLEEEASESIYS-NENDEIDGYTRLNISRVSICIKGLASRSLP 292

  Fly   256 IYDTSIQYAYEESL 269
            :...||...||.||
pombe   293 LTQASITNFYESSL 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rrp4	NP_001286771.1	Rrp4	27..>209	CDD:224022	96/181 (53%)
Rrp4	NP_001286771.1	KH-I	172..290	CDD:412160	39/108 (36%)
SPAC2F7.14c	NP_592984.1	Rrp4	48..295	CDD:224022	111/247 (45%)
		ECR1_N	57..94	CDD:291080	18/36 (50%)
		S1_Rrp4	106..197	CDD:240215	48/90 (53%)
		KH_6	200..240	CDD:292607	19/39 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	130	1.000	Domainoid score	I1333
eggNOG	1	0.900	-	-		E1_COG1097
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6095
Inparanoid	1	1.050	220	1.000	Inparanoid score	I909
OMA	1	1.010	-	-		QHG54120
OrthoFinder	1	1.000	-	-		FOG0004841
OrthoInspector	1	1.000	-	-		oto100627
orthoMCL	1	0.900	-	-		OOG6_101400
Panther	1	1.100	-	-	LDO	PTHR21321
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1222
SonicParanoid	1	1.000	-	-		X3419
TreeFam	1	0.960	-	-
	14	13.860