DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pita and STP3

DIOPT Version :9

Sequence 1:	NP_611806.3	Gene:	pita / 37730	FlyBaseID:	FBgn0034878	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	NP_013479.3	Gene:	STP3 / 851089	SGDID:	S000004367	Length:	343	Species:	Saccharomyces cerevisiae

Alignment Length:	340	Identity:	69/340 - (20%)
Similarity:	104/340 - (30%)	Gaps:	125/340 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 HAYELKVDNNQELSMDDVQSMLEDMASELEKEFPDIPQKA-SPVKPKVLNKSSIRILNKGPAAPV 238
            |:.::...|:....:..||...|..||..|......|.:: ||:. ||...||:.  ..|.:.|.
Yeast    70 HSNDVSRSNSSSSFLPSVQQPTEGSASASETSSSASPSRSISPIL-KVAGPSSVG--GAGVSTPH 131

  Fly   239 EPRLATPKVKRDDSGNVAIVTEVLDSDLPLDDQDDPTKNAEKVATDVFPCPDCERSFPLQQLLEI 303
            ..::..|:.|:.                                     ||.| |:|...  |..
Yeast   132 STKINKPRKKKQ-------------------------------------CPIC-RNFYAN--LTT 156

  Fly   304 HRLNH--TRSRSFQCLLCEKSFFSKYDLAKHNFVHTGERPFKCAICSKAFTRKALLHRH------ 360
            |:..|  ...|..:|.:|.:.|....||.:|.     :|.:|..|.|::    .:|..|
Yeast   157 HKATHLTPEDRPHKCPICHRGFARNNDLLRHK-----KRHWKDEILSQS----GVLSNHNDGKGG 212

  Fly   361 ------ERTHTDVPKFICVYCEK--PFLSRQEMEKHAERHQKKRPFQC----------------- 400
                  :.||           ||  |..|..:..:....||.|..|:|
Yeast   213 SVSPNDDDTH-----------EKMTPMNSVTDYAQLKSLHQIKGTFKCPFNSTLIQLDMDMYPYK 266

  Fly   401 --------------GVCTKSFAFKQGLE--RHETVHSTN------LPFPCQHCERSFSTASKLAR 443
                          ||.::...||..|:  ..|....|.      :|..|:||...|.....
Yeast   267 LKPLNFETSNCHQTGVFSRCDTFKNHLKALHFEYPPGTKKKDRNVVPGRCKHCGLKFENVDV--- 328

  Fly   444 HLVAHAGKRAYPCKY 458
            .|..|.||:   |.|
Yeast   329 WLNEHVGKQ---CGY 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pita	NP_611806.3	zf-AD	17..92	CDD:214871
		COG5048	<281..506	CDD:227381	50/233 (21%)
		C2H2 Zn finger	288..308	CDD:275368	7/19 (37%)
		C2H2 Zn finger	316..336	CDD:275368	6/19 (32%)
		zf-H2C2_2	328..353	CDD:290200	7/24 (29%)
		C2H2 Zn finger	344..364	CDD:275368	4/31 (13%)
		C2H2 Zn finger	372..388	CDD:275370	4/17 (24%)
		C2H2 Zn finger	400..420	CDD:275368	7/52 (13%)
		C2H2 Zn finger	428..448	CDD:275368	5/19 (26%)
		C2H2 Zn finger	456..476	CDD:275368	2/3 (67%)
		C2H2 Zn finger	486..506	CDD:275368
		HARE-HTH	<566..625	CDD:294801
STP3	NP_013479.3	COG5048	<137..295	CDD:227381	39/217 (18%)
		C2H2 Zn finger	144..161	CDD:275368	7/19 (37%)
		C2H2 Zn finger	171..191	CDD:275368	6/24 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100