Protein Alignment pita and ZNF84

DIOPT Version :10

• Sequence 1: NP_611806.3
• Gene: pita / 37730
• FlyBaseID: FBgn0034878
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_003419.3
• Gene: ZNF84 / 7637
• HGNCID: 13159
• Length: 738
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 96/300 - (32%)
• Similarity: 146/300 - (48%)
• Gaps: 8/300 - (2%)

  Fly   277 NAEKVAT--DVFPCPDCERSFPLQQLLEIHRLNHTRSRSFQCLLCEKSFFSKYDLAKHNFVHTGE 339
            |.:::.|  ..|.|.:|.::|..:..|..|...||.::.|.|..|.|:||.|.:|.:|..:||||
Human   336 NHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGE 400

  Fly   340 RPFKCAICSKAFTRKALLHRHERTHTDVPKFICVYCEKPFLSRQEMEKHAERHQKKRPFQCGVCT 404
            :|::|:.|.|||..::.|..|:||||......|:.|.|.|..:..:..|...|..::||.|..|.
Human   401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCG 465

  Fly   405 KSFAFKQGLERHETVHSTNLPFPCQHCERSFSTASKLARHLVAHAGKRAYPCKYCHKSYMLSHHL 469
            |:|:.|..|.||:..|:...|:.|..|.::||....|..|...|.|::.|.|..|.|::....||
Human   466 KAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHL 530

  Fly   470 SRHLRTHTQTSDASFVCSECKVSYSNYNDLLDHALIH-ATASLKCPMCRKQIEDIDSVESHMDQH 533
            ..|.|||  |.:..:.||||..::...:.|..|...| .....:|..|.|.......:.:|...|
Human   531 ISHQRTH--TGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIH 593

  Fly   534 KQSERHACEFCDHIFLTQKCLQRHIEDDHVVEMEPYQ-NE 572
            ...:.:.|..|...|..:..|.||:. .|..| :||: ||
Human   594 TGEKPYECSLCRKAFFEKSELIRHLR-THTGE-KPYECNE 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pita	NP_611806.3	zf-AD	17..92	CDD:214871
		COG5048	<281..506	CDD:227381	77/226 (34%)
		C2H2 Zn finger	288..308	CDD:275368	5/19 (26%)
		C2H2 Zn finger	316..336	CDD:275368	8/19 (42%)
		C2H2 Zn finger	344..364	CDD:275368	8/19 (42%)
		C2H2 Zn finger	372..388	CDD:275370	4/15 (27%)
		C2H2 Zn finger	400..420	CDD:275368	8/19 (42%)
		C2H2 Zn finger	428..448	CDD:275368	6/19 (32%)
		C2H2 Zn finger	456..476	CDD:275368	7/19 (37%)
		C2H2 Zn finger	486..506	CDD:275368	6/19 (32%)
ZNF84	NP_003419.3	KRAB	9..68	CDD:214630
		C2H2 Zn finger	209..229	CDD:275368
		C2H2 Zn finger	237..257	CDD:275368
		zf-C2H2	263..285	CDD:395048
		C2H2 Zn finger	265..285	CDD:275368
		zf-H2C2_2	278..302	CDD:463886
		C2H2 Zn finger	293..313	CDD:275368
		COG5048	317..724	CDD:227381	95/299 (32%)
		C2H2 Zn finger	321..341	CDD:275368	1/4 (25%)
		C2H2 Zn finger	349..369	CDD:275368	5/19 (26%)
		C2H2 Zn finger	377..397	CDD:275368	8/19 (42%)
		C2H2 Zn finger	405..425	CDD:275368	8/19 (42%)
		C2H2 Zn finger	433..453	CDD:275368	5/19 (26%)
		C2H2 Zn finger	461..481	CDD:275368	8/19 (42%)
		C2H2 Zn finger	489..509	CDD:275368	6/19 (32%)
		C2H2 Zn finger	517..537	CDD:275368	7/19 (37%)
		C2H2 Zn finger	545..565	CDD:275368	6/19 (32%)
		C2H2 Zn finger	573..593	CDD:275368	4/19 (21%)
		C2H2 Zn finger	601..621	CDD:275368	6/20 (30%)
		C2H2 Zn finger	629..649	CDD:275368	1/2 (50%)
		C2H2 Zn finger	657..677	CDD:275368
		C2H2 Zn finger	685..705	CDD:275368
		C2H2 Zn finger	713..733	CDD:275368