DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pita and CG11902

DIOPT Version :9

Sequence 1:	NP_611806.3	Gene:	pita / 37730	FlyBaseID:	FBgn0034878	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	NP_651389.3	Gene:	CG11902 / 43070	FlyBaseID:	FBgn0028647	Length:	1426	Species:	Drosophila melanogaster

Alignment Length:	648	Identity:	131/648 - (20%)
Similarity:	210/648 - (32%)	Gaps:	226/648 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 AEPSETPK-------KLLNTMAKSS-SQVIIEDVQVLESAMVTPRTVAGSSPVPRRSHAYELKVD 182
            ||..:.|.       .|.||:.|.. :::|:.|||   ......|.:         |...|..::
  Fly   789 AEDRDIPSASKAFYPDLENTLEKDELAEMIMADVQ---REFDLDRFI---------SITNEAGLE 841

  Fly   183 NNQELSMDDVQSMLEDMASEL-----------------------EKEFPDIPQKASPVKPKVLNK 224
            .|.|.|..|.:|..||..|.|                       |.::.:.....|..:.:.:|:
  Fly   842 LNLESSETDTESEQEDNHSSLNYPCNLCTTVVKRKHQLYAHQLEEHKWEEAVLVCSNCQTRFVNE 906

  Fly   225 SSI----RILNKGPAAPVEPRLATPKVKRDDSGNVAIVTEVLDSDLPLDDQDDPTKNAEKVATDV 285
            |.:    |.|...|....:.|....:.:..:  |:.:..||......|..|||    ..||..|:
  Fly   907 SLLDHHSRTLCHNPQKLFQCRKCPLRFRWRE--NLKLHMEVFHMLDELSIQDD----LPKVDGDL 965

  Fly   286 FPCPDCERSFPLQQLLEIHRLNH-TRSRSFQCLLCEKSFFSKYDLAKH----------------- 332
             .|..|.|||.:|:.|..|.|.| ..|..|:|..|.:.|:.:.:|.:|
  Fly   966 -QCGKCNRSFRMQKDLTRHTLMHGQESNIFRCRWCARRFYRRANLLQHIARHGISVSQLPYAEAI 1029

  Fly   333 --NFVHTGER-PFKCAICSKAFTRKALLHRH---------------------------------- 360
              ::|:.|.| ..:|.:|:.:|...|.|..|
  Fly  1030 LDSYVNPGGRKKVECRVCNVSFPTIAALRLHLETMPAGSHHDYSSLQNYSITNQMGFEMDLYDSE 1094

  Fly   361 -----ERTHTDVP----KFICVYCEKPFLSRQEMEKHAE-------------------------R 391
                 .|||...|    .:.|..|:...|.:.|:.:|.:                         .
  Fly  1095 TDDEDSRTHIKPPGAPSSYTCNMCQLRCLRKFELYQHQQAMHRMEKISDGCDSCLFKSVCPEIIS 1159

  Fly   392 HQKK--------------------------------------------------------RPFQC 400
            |.|:                                                        :.|||
  Fly  1160 HHKRTQCENREKQFKCTRCGYKFMWESNLLLHMDLQHVKTEDQELDESKEASGDEPKTEGQVFQC 1224

  Fly   401 GVCTKSFAFKQGLERH-----------ETVHSTNLP--------FPCQHCERSFSTASKLARHLV 446
            |:||:.:..|..|..|           .|..:.|.|        |.|..|.::.|::|.|..|:.
  Fly  1225 GLCTRKYNRKDRLTAHLKKFHGPDCKPSTAKTPNRPISPKEPKRFLCAFCGKAVSSSSNLIIHMR 1289

  Fly   447 AHAGKRAYPCKYCHKSYMLSHHLSRHLRTHTQTSDASFVCSECKVSYSNYNDLLDHALIHA-TAS 510
            .|.|::.:.|:||..::..|..|..|.|||  |.:...||:.|:..::....|..|..||: ...
  Fly  1290 RHTGEKPFKCEYCTMAFPRSSDLQCHRRTH--TGERPHVCTVCQKGFARSYKLQQHMRIHSGERP 1352

  Fly   511 LKCPMCRKQIEDIDSVESHMDQHKQSERHACEFCDHIFLTQKCLQRH-IEDDHVVE----MEP 568
            .||..|.|.....:.:..|:.:|.....:.|..|...|:....|:.| ::..|..|    :||
  Fly  1353 YKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRMQQSHYEEGQESVEP 1415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pita	NP_611806.3	zf-AD	17..92	CDD:214871
		COG5048	<281..506	CDD:227381	75/388 (19%)
		C2H2 Zn finger	288..308	CDD:275368	9/19 (47%)
		C2H2 Zn finger	316..336	CDD:275368	5/38 (13%)
		zf-H2C2_2	328..353	CDD:290200	8/44 (18%)
		C2H2 Zn finger	344..364	CDD:275368	7/58 (12%)
		C2H2 Zn finger	372..388	CDD:275370	4/15 (27%)
		C2H2 Zn finger	400..420	CDD:275368	8/30 (27%)
		C2H2 Zn finger	428..448	CDD:275368	6/19 (32%)
		C2H2 Zn finger	456..476	CDD:275368	7/19 (37%)
		C2H2 Zn finger	486..506	CDD:275368	4/19 (21%)
		HARE-HTH	<566..625	CDD:294801	2/3 (67%)
CG11902	NP_651389.3	zf-AD	6..83	CDD:285071
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	384..405	CDD:275368
		C2H2 Zn finger	417..437	CDD:275368
		C2H2 Zn finger	447..463	CDD:275368
		C2H2 Zn finger	578..599	CDD:275368
		C2H2 Zn finger	610..629	CDD:275368
		C2H2 Zn finger	640..660	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	706..726	CDD:275368
		C2H2 Zn finger	762..782	CDD:275368
		C2H2 Zn finger	866..887	CDD:275368	0/20 (0%)
		C2H2 Zn finger	896..918	CDD:275368	5/21 (24%)
		C2H2 Zn finger	926..947	CDD:275368	4/22 (18%)
		C2H2 Zn finger	967..987	CDD:275368	9/19 (47%)
		C2H2 Zn finger	996..1016	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1044..1063	CDD:275368	6/18 (33%)
		C2H2 Zn finger	1224..1244	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1271..1291	CDD:275368	6/19 (32%)
		zf-H2C2_2	1283..1306	CDD:290200	7/22 (32%)
		COG5048	1295..>1367	CDD:227381	21/73 (29%)
		C2H2 Zn finger	1299..1319	CDD:275368	7/19 (37%)
		zf-H2C2_2	1311..1336	CDD:290200	9/26 (35%)
		C2H2 Zn finger	1327..1347	CDD:275368	4/19 (21%)
		zf-H2C2_2	1340..1364	CDD:290200	8/23 (35%)
		C2H2 Zn finger	1355..1375	CDD:275368	4/19 (21%)
		zf-H2C2_2	1367..1392	CDD:290200	5/24 (21%)
		C2H2 Zn finger	1383..1401	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100