DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pita and CG6813

DIOPT Version :9

Sequence 1:	NP_611806.3	Gene:	pita / 37730	FlyBaseID:	FBgn0034878	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster

Alignment Length:	451	Identity:	93/451 - (20%)
Similarity:	145/451 - (32%)	Gaps:	190/451 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 CRFCLTEQKLASIFEENPRVKTTANLPLQIMAITAIEVYAGDGMPGHICLECRLLFEHCYRFKQM 82
            ||.|........:|...     ..:|..||.:||.:|:.....:.|.:|..|....:...:|:|.
  Fly     6 CRICSRSDAPIDLFGPG-----NGHLVRQIHSITGVELSCKKEISGQMCTTCLDNLQAAIKFRQR 65

  Fly    83 CKRAETLLRQYPLTGNWPSPLEKPRAPMTMVASKKLLVVPAKTAEPSETPKKLLNTMAKSSSQVI 147
            |                            ::|.|:.|       |..|...|..:|     ..:|
  Fly    66 C----------------------------IIAEKQNL-------ERIECDSKDCST-----DPII 90

  Fly   148 IEDVQVLESAMVTPRTVAGSSPVPRRSHAYELKVDNNQELSMDDVQSMLEDMASELEKEFPDIPQ 212
            .||                              :|:||             :.|||::.
  Fly    91 YED------------------------------IDDNQ-------------IESELDES------ 106

  Fly   213 KASPVKPKVLNKSSIRILNKGPAAPVEPRLATPKVKRDDSGNVAIVTEVLDSDLPLDDQDDPTKN 277
                                         :..|:||                |||:       .:
  Fly   107 -----------------------------ILCPEVK----------------DLPM-------PS 119

  Fly   278 AEKVA--------------TDVFPCPDCERSFPLQQLLEIHRLNHTRSRSFQC--LLCEKSFFSK 326
            ||||:              |..:.||||.|....:...:.|.|.||..::|.|  |.||:||.::
  Fly   120 AEKVSAPTSLNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATR 184

  Fly   327 YDLAKHNFVHTGERPFKCAICSKAFTRKALLHRHERTHTDVPKFICVYCEKPFLSRQEMEKHAER 391
            .:|..|..:||||:|                            ::||||.:.|.|....::|..|
  Fly   185 KELTSHTRIHTGEQP----------------------------YVCVYCPRRFSSSGARQEHHRR 221

  Fly   392 HQKKRPFQCGVCTKSFAFKQGLERHETVHSTNLPFPCQHCERSFSTASKLARHLVAHAGKR 452
            |:.:|.::|..|.|||.....|.:|:.:|.......|..|::.|...|.|..||.::..||
  Fly   222 HRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIHKR 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pita	NP_611806.3	zf-AD	17..92	CDD:214871	16/73 (22%)
		COG5048	<281..506	CDD:227381	52/188 (28%)
		C2H2 Zn finger	288..308	CDD:275368	7/19 (37%)
		C2H2 Zn finger	316..336	CDD:275368	8/21 (38%)
		zf-H2C2_2	328..353	CDD:290200	7/24 (29%)
		C2H2 Zn finger	344..364	CDD:275368	0/19 (0%)
		C2H2 Zn finger	372..388	CDD:275370	6/15 (40%)
		C2H2 Zn finger	400..420	CDD:275368	7/19 (37%)
		C2H2 Zn finger	428..448	CDD:275368	7/19 (37%)
		C2H2 Zn finger	456..476	CDD:275368
		C2H2 Zn finger	486..506	CDD:275368
		HARE-HTH	<566..625	CDD:294801
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	19/109 (17%)
		C2H2 Zn finger	144..164	CDD:275368	7/19 (37%)
		C2H2 Zn finger	172..194	CDD:275368	8/21 (38%)
		zf-H2C2_2	186..211	CDD:290200	12/52 (23%)
		UFD2	<256..>294	CDD:227443	9/27 (33%)
		C2H2 Zn finger	258..280	CDD:275368	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050