DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pita and CG12391

DIOPT Version :9

Sequence 1:	NP_611806.3	Gene:	pita / 37730	FlyBaseID:	FBgn0034878	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	NP_610639.1	Gene:	CG12391 / 36170	FlyBaseID:	FBgn0033581	Length:	587	Species:	Drosophila melanogaster

Alignment Length:	433	Identity:	90/433 - (20%)
Similarity:	156/433 - (36%)	Gaps:	111/433 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AKLEVREAMLTE---KRVCRFCLTEQKLASIFEENPRVKTTANLPLQIMAITA--IEVYAGDGMP 62
            |.:.:||....|   :..||.|.::::|..:|::  ::..|   |..::.:..  :.:...|.||
  Fly   223 ADVPIRERKKEEPVDEDQCRVCTSKEELVCLFKK--QIDAT---PADMLLVICPNVSILPKDFMP 282

  Fly    63 GHICLECRLLFEHCYRFKQMCKRAETLLRQYPLTGNWPSPLEKPRAPMTMVASKKLLVVPAKTAE 127
            ..||.:|........:.::..:..:..||:  ......:.:.:||.         .:|:.|...:
  Fly   283 QFICTKCMGSLTIAIQLRKQLETTDQELRK--RLSRSKNKVRRPRG---------YVVIDAPVTD 336

  Fly   128 PSETPKKLLNTMAKSSSQVIIEDVQVLESAMVTPRTVAGSSPVPRRSHAYELKVDNNQELSMDDV 192
            .||...:|       ..:..:.||....||                         ::.....||
  Fly   337 SSEDEDEL-------DDEFKVSDVAGTTSA-------------------------DSDSADSDD- 368

  Fly   193 QSMLEDMASELEKEFPDIPQKASPVKPKVLNKSSIRILNKGPAAPVEPRLATPKVKRDDSGNVAI 257
                    ||.||:.|. |:.....||          |.:|..:..||..|..|
  Fly   369 --------SEKEKKKPG-PRGRPRKKP----------LKRGTDSDGEPSSAQKK----------- 403

  Fly   258 VTEVLDSDLPLDDQDDPTKNAEKVATDVFPCPDCERSFPLQQLLEIHRLNHTRSRSFQCLLCEKS 322
                         :..|:..|   :...|.||:|:.:|..:|...:||..|.|. ...|.:|.|.
  Fly   404 -------------KYQPSSTA---SVGPFECPNCDLTFSRKQSYVLHRKTHERI-EHACPICGKK 451

  Fly   323 FFSKYDLAKHNFVHTGERP-FKCAICSKAFTRKALLHRHERTHTDVPKFI--CVYCEKPFLSRQE 384
            |..::....|...|..||. |:|.:|.|.|..:|.|..|.....|...||  |..|::.||::|.
  Fly   452 FKVEWAYKTHMQRHEQERAHFRCELCPKIFRLRAELKHHMAQRHDEHGFIYECKRCQRTFLTQQR 516

  Fly   385 MEKH----AERHQKKRPFQCGVCTKSFAFKQGLERHETVHSTN 423
            :::|    .:||::.   ...:..:...|||.....:..|..|
  Fly   517 LQRHQAVGCQRHKED---SVRIKEEQSRFKQESRSKDDRHHGN 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pita	NP_611806.3	zf-AD	17..92	CDD:214871	14/76 (18%)
		COG5048	<281..506	CDD:227381	42/150 (28%)
		C2H2 Zn finger	288..308	CDD:275368	7/19 (37%)
		C2H2 Zn finger	316..336	CDD:275368	5/19 (26%)
		zf-H2C2_2	328..353	CDD:290200	9/25 (36%)
		C2H2 Zn finger	344..364	CDD:275368	7/19 (37%)
		C2H2 Zn finger	372..388	CDD:275370	5/15 (33%)
		C2H2 Zn finger	400..420	CDD:275368	3/19 (16%)
		C2H2 Zn finger	428..448	CDD:275368
		C2H2 Zn finger	456..476	CDD:275368
		C2H2 Zn finger	486..506	CDD:275368
		HARE-HTH	<566..625	CDD:294801
CG12391	NP_610639.1	zf-AD	240..313	CDD:285071	15/79 (19%)
		zf-C2H2	416..438	CDD:278523	8/21 (38%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		zf-C2H2	443..465	CDD:278523	5/21 (24%)
		C2H2 Zn finger	445..465	CDD:275368	5/19 (26%)
		C2H2 Zn finger	474..491	CDD:275368	6/16 (38%)
		C2H2 Zn finger	504..521	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100