DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment pita and Plzf

DIOPT Version :9

Sequence 1:NP_611806.3 Gene:pita / 37730 FlyBaseID:FBgn0034878 Length:683 Species:Drosophila melanogaster
Sequence 2:NP_001285862.1 Gene:Plzf / 34622 FlyBaseID:FBgn0032401 Length:469 Species:Drosophila melanogaster


Alignment Length:408 Identity:89/408 - (21%)
Similarity:154/408 - (37%) Gaps:72/408 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   183 NNQ-----------ELSMDDVQSM-LEDMASELEKEFPDIPQKA------SPVKPKVLNKSSIRI 229
            |||           ||..||..|: :.......:.:|.:..||.      :|:|..:.|.|..:.
  Fly    26 NNQRRTGQFCDLLLELDSDDSLSLSVHFCVLAAQSQFINSNQKQQQFSIHNPLKITIRNFSCTQC 90

  Fly   230 LNKGPAAPVEPRLATPK---VKRDDSGNVAIVTEVLD-------------SDLPLDDQDDPTKNA 278
            |:.......|..::..|   :...:...:..|||:|:             :::|...:..|..:.
  Fly    91 LHTIVDFFYEDLVSVSKEHELHFRELAQILAVTELLNLYQLQPLGEAKEATEIPAPGEAQPNPDP 155

  Fly   279 EKVATDVFP----------------------CPDCE-RSFPLQQLLEIHRLNHTRSRSFQCLLCE 320
            ||.|..||.                      |..|: :.:.:|:::|  .:.........|.|||
  Fly   156 EKKAEAVFENRQSYFKLKNPRAVKSSSKVNYCIGCDFKCYQVQKMIE--HMGSCEPSHLICSLCE 218

  Fly   321 KSFFSKYDLAKHNFVHTGE--RPFKCAICSKAFTRKALLHRHERTHTDVPKFICVYCEKPFLSRQ 383
            ..|....:...|...|:|:  :||.|..|...|..:|.|..|:..|:.....||.:|.|.|..:|
  Fly   219 VGFLDWREYDTHLRRHSGDLRKPFFCLQCGIRFNTRAALLVHQPKHSTETPHICPHCGKGFKWKQ 283

  Fly   384 EMEKHAERHQKKRPFQCGVCTKSFAFKQGLERHETVHSTNLPFPC--QHCERSFSTASKLARHLV 446
            .:..|...|..::...|.||..|....:.|:.|:.:|:... |.|  ..|:...:....|..|:.
  Fly   284 GLSNHILVHNPEKQMLCDVCGYSTTHMKALKSHKLLHTGEF-FACTVSGCKHRANRKENLKLHIE 347

  Fly   447 AHAGKRAYPCKYCHKSYMLSHHLSRHLRTHTQTSDASFVCSECKVSYSNYNDLLDHA-LIHATAS 510
            .|...|.:.|:.|...:..|.:|.||...||:.....:.|..|..|....:.:.:|. .:|....
  Fly   348 THKQGRDFICEVCGCKFSQSKNLKRHALKHTENGPNRYKCQLCGFSSHRSDKMKEHVQRVHTEKP 412

  Fly   511 LKCPMCRKQIEDIDSVES 528
            :       |:|..::|:|
  Fly   413 V-------QLELSETVDS 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pitaNP_611806.3 zf-AD 17..92 CDD:214871
COG5048 <281..506 CDD:227381 58/252 (23%)
C2H2 Zn finger 288..308 CDD:275368 4/20 (20%)
C2H2 Zn finger 316..336 CDD:275368 6/19 (32%)
zf-H2C2_2 328..353 CDD:290200 8/26 (31%)
C2H2 Zn finger 344..364 CDD:275368 6/19 (32%)
C2H2 Zn finger 372..388 CDD:275370 5/15 (33%)
C2H2 Zn finger 400..420 CDD:275368 6/19 (32%)
C2H2 Zn finger 428..448 CDD:275368 4/21 (19%)
C2H2 Zn finger 456..476 CDD:275368 6/19 (32%)
C2H2 Zn finger 486..506 CDD:275368 4/20 (20%)
HARE-HTH <566..625 CDD:294801
PlzfNP_001285862.1 COG5048 <193..403 CDD:227381 52/212 (25%)
C2H2 Zn finger 214..234 CDD:275368 6/19 (32%)
C2H2 Zn finger 244..264 CDD:275368 6/19 (32%)
C2H2 Zn finger 272..292 CDD:275368 6/19 (32%)
C2H2 Zn finger 300..320 CDD:275368 6/19 (32%)
C2H2 Zn finger 330..349 CDD:275368 3/18 (17%)
C2H2 Zn finger 357..377 CDD:275368 6/19 (32%)
C2H2 Zn finger 387..408 CDD:275368 4/20 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45446664
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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