DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pita and CG8944

DIOPT Version :9

Sequence 1:	NP_611806.3	Gene:	pita / 37730	FlyBaseID:	FBgn0034878	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	NP_573065.1	Gene:	CG8944 / 32517	FlyBaseID:	FBgn0030680	Length:	762	Species:	Drosophila melanogaster

Alignment Length:	335	Identity:	74/335 - (22%)
Similarity:	116/335 - (34%)	Gaps:	100/335 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 LDSDLPLDDQDDPTKNAEKVATDVFPCPDCERSFPLQQLLEIHRLNHTRS--RSFQCLLCEKSFF 324
            :|.|:|                 .|.|..|.......:.|::|.|.|..|  ..:.|.:|...|.
  Fly   467 MDDDIP-----------------PFKCAHCPEIVQTLRELDLHMLTHQPSLGGGYYCNICSIQFH 514

  Fly   325 SKYDLAKHNFVHTG---ERPFKCAICSKAFTRKALLHRHERTHTD---VPKF------------- 370
            :..:...|..:|.|   |..|.|.:|:.:|..||....|.|.|.:   :|..
  Fly   515 NAQEFDNHKQLHLGGVTEIKFNCELCTASFREKANYDEHLRRHNEELFLPSLALNHSIMEGGLGD 579

  Fly   371 --ICVYCEKPFLSRQEMEKHAERHQKKRPFQCGVCTKSFAFKQGLERHETV----------HSTN 423
              |.|..|:   ||....:...||..|            |....::..:.:          ..|:
  Fly   580 DEIGVEGEE---SRGSGSRRKRRHAAK------------ATDDMVDDDDRIGGGGGGGSGGGGTD 629

  Fly   424 L--PFPCQHCERSFSTASKLARHLVAHAG--KRAYPCKY--CHKSYMLSHHLSRHLRTHTQTSDA 482
            :  |:.|..|.|||:|...|..|.:.|..  :|.|.|.|  |:||::..:.|..||:.|
  Fly   630 IAKPYGCDVCRRSFATPGHLNAHRIVHQDERERCYKCDYPQCNKSFVARNSLFEHLKQH------ 688

  Fly   483 SFVCSECKVSYSNYNDLLDHALIHATASLKCPMCRKQIEDIDSVESHMDQHKQSERHACEFCDHI 547
                      |||             ...||.:|.|..:...::::|...|.:.:|:.|:.|...
  Fly   689 ----------YSN-------------EEFKCDICGKTFKSTKNLQNHKQIHDKIKRYVCQICGSA 730

  Fly   548 FLTQKCLQRH 557
            |.....|..|
  Fly   731 FAQAAGLYLH 740

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pita	NP_611806.3	zf-AD	17..92	CDD:214871
		COG5048	<281..506	CDD:227381	59/263 (22%)
		C2H2 Zn finger	288..308	CDD:275368	5/19 (26%)
		C2H2 Zn finger	316..336	CDD:275368	4/19 (21%)
		zf-H2C2_2	328..353	CDD:290200	8/27 (30%)
		C2H2 Zn finger	344..364	CDD:275368	7/19 (37%)
		C2H2 Zn finger	372..388	CDD:275370	4/15 (27%)
		C2H2 Zn finger	400..420	CDD:275368	1/29 (3%)
		C2H2 Zn finger	428..448	CDD:275368	8/19 (42%)
		C2H2 Zn finger	456..476	CDD:275368	8/21 (38%)
		C2H2 Zn finger	486..506	CDD:275368	3/19 (16%)
		HARE-HTH	<566..625	CDD:294801
CG8944	NP_573065.1	MADF_DNA_bdg	259..344	CDD:287510
		MADF	379..472	CDD:214738	2/4 (50%)
		C2H2 Zn finger	476..496	CDD:275368	5/19 (26%)
		C2H2 Zn finger	506..526	CDD:275368	4/19 (21%)
		C2H2 Zn finger	537..557	CDD:275368	7/19 (37%)
		C2H2 Zn finger	636..656	CDD:275368	8/19 (42%)
		zf-C2H2_8	639..712	CDD:292531	26/101 (26%)
		C2H2 Zn finger	666..688	CDD:275368	8/21 (38%)
		zf-C2H2	694..716	CDD:278523	5/21 (24%)
		C2H2 Zn finger	696..716	CDD:275368	4/19 (21%)
		zf-H2C2_2	708..733	CDD:290200	6/24 (25%)
		C2H2 Zn finger	724..744	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100