DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pita and si:dkeyp-2e4.6

DIOPT Version :9

Sequence 1:	NP_611806.3	Gene:	pita / 37730	FlyBaseID:	FBgn0034878	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	NP_001124126.1	Gene:	si:dkeyp-2e4.6 / 100002333	ZFINID:	ZDB-GENE-061009-50	Length:	271	Species:	Danio rerio

Alignment Length:	275	Identity:	74/275 - (26%)
Similarity:	110/275 - (40%)	Gaps:	48/275 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 PDIPQKASPVKPKVLNKSSIRILNKGPAAPVEPRLATPKVKRDDSGNVAIVTEVLDSDLPLDDQD 272
            |:.....:.|:..||:|:      :|.||....||.. :||.|::                .||.
Zfish    39 PESKSTNNDVETLVLSKT------EGSAALFCRRLKY-RVKTDET----------------SDQS 80

  Fly   273 DPTKNAEKVATDVFPCPDCERSFPLQQLLEIHRLNHTRSRSFQCLLCEKSFFSKYDLAKHNFVHT 337
            .|.             .|.|...|:.       .:.|..:.|.|.||...|....::.:|..:||
Zfish    81 SPD-------------TDTEDELPIS-------TSPTPGKKFVCKLCGFEFTYNSNMVRHMRIHT 125

  Fly   338 GERPFKCAICSKAFTRKALLHRHERTHTDVPK-----FICVYCEKPFLSRQEMEKHAERHQKKRP 397
            .|.|:.|.||.|.|.|:..|..|...||.|.:     |.|..|.|.|.....::.|..:|:.:||
Zfish   126 EETPYVCEICGKGFKRQDWLKLHISVHTGVKRKRKKTFGCDQCGKKFHGSTALQSHLNKHRGERP 190

  Fly   398 FQCGVCTKSFAFKQGLERHETVHSTNLPFPCQHCERSFSTASKLARHLVAHAGKRAYPCKYCHKS 462
            |.|..|.|||.....|.||.....:.....|..|...|:..:.|.:|:..|.|:|.|.|.:|.|:
Zfish   191 FPCVQCDKSFFSHSDLYRHINDCHSQKKHSCSLCGNGFTRRTSLLKHMRIHTGERPYSCPHCGKT 255

  Fly   463 YMLSHHLSRHLRTHT 477
            :...:....||:.|:
Zfish   256 FPYKYSFEMHLKRHS 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pita	NP_611806.3	zf-AD	17..92	CDD:214871
		COG5048	<281..506	CDD:227381	58/202 (29%)
		C2H2 Zn finger	288..308	CDD:275368	3/19 (16%)
		C2H2 Zn finger	316..336	CDD:275368	5/19 (26%)
		zf-H2C2_2	328..353	CDD:290200	10/24 (42%)
		C2H2 Zn finger	344..364	CDD:275368	8/19 (42%)
		C2H2 Zn finger	372..388	CDD:275370	4/15 (27%)
		C2H2 Zn finger	400..420	CDD:275368	8/19 (42%)
		C2H2 Zn finger	428..448	CDD:275368	5/19 (26%)
		C2H2 Zn finger	456..476	CDD:275368	5/19 (26%)
		C2H2 Zn finger	486..506	CDD:275368
		HARE-HTH	<566..625	CDD:294801
si:dkeyp-2e4.6	NP_001124126.1	COG5048	<98..256	CDD:227381	51/157 (32%)
		C2H2 Zn finger	104..124	CDD:275368	5/19 (26%)
		zf-H2C2_2	116..141	CDD:290200	10/24 (42%)
		C2H2 Zn finger	132..152	CDD:275368	8/19 (42%)
		C2H2 Zn finger	165..185	CDD:275368	5/19 (26%)
		zf-H2C2_2	177..200	CDD:290200	8/22 (36%)
		C2H2 Zn finger	193..241	CDD:275368	13/47 (28%)
		zf-H2C2_2	233..256	CDD:290200	9/22 (41%)
		C2H2 Zn finger	249..269	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910