Protein Alignment Dcp-1 and CASP6

DIOPT Version :10

• Sequence 1: NP_476974.1
• Gene: Dcp-1 / 37729
• FlyBaseID: FBgn0010501
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001217.2
• Gene: CASP6 / 839
• HGNCID: 1507
• Length: 293
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 102/266 - (38%)
• Similarity: 142/266 - (53%)
• Gaps: 21/266 - (7%)

  Fly    68 ASEYNMSHKHRGVALIFNHE-FFDIPSLKSRTGTNVDAQELKKAFENLGFAVSVHKDCKLRDILK 131
            |.:|.|.|:.||:||||||| ||...:|..|.||..|...|.:.|.:|||.|....|.|..::|.
Human    34 AEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLL 98

  Fly   132 HVGKAAELDHTDNDCLAVAILSHGEHGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPKLFFIQAC 196
            .:.:.:.:.|.|.||.....|||||..::||.|.:.::..:...|....|.||.||||:|.||||
Human    99 KIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPKIFIIQAC 163

  Fly   197 QGDRLDGGI-----------TLEKGVTETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGS 250
            :|::.|..:           .|:..:||.|  :::.|.:|..||||..||...||:|.|...|||
Human   164 RGNQHDVPVIPLDVVDNQTEKLDTNITEVD--AASVYTLPAGADFLMCYSVAEGYYSHRETVNGS 226

  Fly   251 WYMQSLIRELNANGKKYDLLTLLTFVNQRVA---LDFESNVPATPMMDRQKQIPCLTSMLTRILR 312
            ||:|.|...|...|...:...|||.||::|:   :||..:    |....:||:||..||||:.|.
Human   227 WYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKD----PSAIGKKQVPCFASMLTKKLH 287

  Fly   313 FGDKPN 318
            |..|.|
Human   288 FFPKSN 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	98/256 (38%)
CASP6	NP_001217.2	Disordered. /evidence=ECO:0000269|PubMed:28864531, ECO:0000305|PubMed:30420425	1..20
		CASc	37..290	CDD:214521	99/258 (38%)
		Tri-arginine exosite. /evidence=ECO:0000269|PubMed:30420425	42..44		0/1 (0%)
		130's region. /evidence=ECO:0000269|PubMed:28154009	125..142		3/16 (19%)