Protein Alignment Dcp-1 and CASP1

DIOPT Version :9

• Sequence 1: NP_476974.1
• Gene: Dcp-1 / 37729
• FlyBaseID: FBgn0010501
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001244047.1
• Gene: CASP1 / 834
• HGNCID: 1499
• Length: 404
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 83/337 - (24%)
• Similarity: 135/337 - (40%)
• Gaps: 49/337 - (14%)

  Fly     5 CVTRNYGVGIRSPNGSENRGSFI-MADNTDAKGCTPESLVV---------GGATAASPLPANKFV 59
            |...:|..|....:..:..|::: |.|:.......|....|         .|:.....|.:.:..
Human    77 CEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEA 141

  Fly    60 ARMPVERYASEY---NMSHKHRGVALIFNHEFFDIPSLKSRTGTNVDAQELKKAFENLGFAVSVH 121
            .|:..::.|..|   :.|.:.|...:|.|.||..||   .|||..||...:....:|||::|.|.
Human   142 QRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIP---RRTGAEVDITGMTMLLQNLGYSVDVK 203

  Fly   122 KDCKLRDILKHVGKAAEL-DHTDNDCLAVAILSHG-EHGYLYAKDTQ-----YKLDNIWHYFTAT 179
            |:....|:...:...|.. :|..:|...:..:||| ..|....|.::     .:|:.|::.....
Human   204 KNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTK 268

  Fly   180 FCPSLAGKPKLFFIQACQGDR-----------LDGGITLEKGVTETDGESSTSYKIPIHADFLFS 233
            .||||..|||:..||||:||.           :.|.::|.   |..:.|.....|..|..||:..
Human   269 NCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLP---TTEEFEDDAIKKAHIEKDFIAF 330

  Fly   234 YSTIPGYFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQRVALDFESNVPATPMMDRQK 298
            .|:.|...|||:...||.::..||..:.......|:..:.    ::|...||       ..|.:.
Human   331 CSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIF----RKVRFSFE-------QPDGRA 384

  Fly   299 QIPCLTSM-LTR 309
            |:|....: |||
Human   385 QMPTTERVTLTR 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	71/261 (27%)
CASP1	NP_001244047.1	CARD_CASP1-like	5..87	CDD:260036	3/9 (33%)
		CASc	153..402	CDD:214521	71/261 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910