DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dcp-1 and Casp7

DIOPT Version :9

Sequence 1:	NP_476974.1	Gene:	Dcp-1 / 37729	FlyBaseID:	FBgn0010501	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_071596.1	Gene:	Casp7 / 64026	RGDID:	620944	Length:	303	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	124/296 - (41%)
Similarity:	176/296 - (59%)	Gaps:	24/296 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DNTDAKGCTPE------SLVVGGATAASPLPANKFVARMPVERYASEYNMSHKHRGVALIFNHEF 88
            |..|||   |:      ||:......||..|.:....|:|.  |.  |.|..:..|..:|.|::.
  Rat    20 DGVDAK---PDRSTIISSLLWKKKKNASMCPVSTTRDRVPT--YL--YRMDFEKMGKCIIINNKN 77

  Fly    89 FD-IPSLKSRTGTNVDAQELKKAFENLGFAVSVHKDC---KLRDILKHVGKAAELDHTDNDCLAV 149
            || ...:..|.||:.||:.|.|.|.:|||.|:|:.||   |::|:|:   :|:|.||:::.|.|.
  Rat    78 FDKATGMDVRNGTDKDAEALFKCFRSLGFEVTVYNDCSCAKMQDLLR---RASEEDHSNSACFAC 139

  Fly   150 AILSHGEHGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPKLFFIQACQGDRLDGGITLEKG-VTE 213
            .:|||||...:|.||....:.::..:|....|.:|..||||||||||:|..||.||..:.| :.:
  Rat   140 VLLSHGEENLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPIND 204

  Fly   214 TDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQ 278
            ||  ::..||||:.|||||:|||:|||:||||...|||::|:|...||.:||..:::.:||.||.
  Rat   205 TD--ANPRYKIPVEADFLFAYSTVPGYYSWRNPGKGSWFVQALCSILNEHGKDLEIMQILTRVND 267

  Fly   279 RVALDFESNVPATPMMDRQKQIPCLTSMLTRILRFG 314
            |||..|||. ...|..:.:|||||:.||||:.|.||
  Rat   268 RVARHFESQ-SDDPRFNEKKQIPCMVSMLTKELYFG 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	109/246 (44%)
Casp7	NP_071596.1	CASc	60..301	CDD:237997	109/246 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340693
Domainoid	1	1.000	203	1.000	Domainoid score	I2862
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11168
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3582
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	1	1.000	-	-		mtm8999
orthoMCL	1	0.900	-	-		OOG6_103710
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X460
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.800