DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dcp-1 and caspbl

DIOPT Version :9

Sequence 1:	NP_476974.1	Gene:	Dcp-1 / 37729	FlyBaseID:	FBgn0010501	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001139064.1	Gene:	caspbl / 566185	ZFINID:	ZDB-GENE-090311-53	Length:	409	Species:	Danio rerio

Alignment Length:	322	Identity:	73/322 - (22%)
Similarity:	140/322 - (43%)	Gaps:	66/322 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 PESLVVGGATAASPLPAN------------KFVARMPVERYASEYNMS---H------------- 75
            |:|:...|:....|:.::            :|..|:   .||:..:.|   |
Zfish   104 PQSINTSGSDELEPIQSDWQRPRGIINRFQEFKTRL---LYANRDDASISIHFYKQNTLSIYTPV 165

  Fly    76 ---KHRGVALIFNHEFFDIPSLKSRTGTNVDAQELKKAFENLGFAVSVHKDCKLRDILKHVGK-A 136
               :.:|:||:..:..| ......|.|...|.:.::...:||.|.|..:::....:|.:.|.. :
Zfish   166 SRTQRKGLALLITNILF-ANKQDDRAGAERDEENMEWLLKNLNFMVIKYRNLTGNEISRAVQDFS 229

  Fly   137 AELDHTDNDCLAVAILSHGE------------HGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPK 189
            ...:|.|.|...|.|:|||:            :.:|..::..|.:::.:.:..:..||:|..|||
Zfish   230 RRHEHQDADSTFVVIMSHGDRIQNKDAILGVNYNWLQNRNDVYFVEDTFSHLNSVNCPALIDKPK 294

  Fly   190 LFFIQACQGDRLDGGITLEKGVTETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGSWYMQ 254
            :..||||:|.:| ||:.::..|.|:|   |..:|   ..||:...||:|...::|:...||:::.
Zfish   295 VILIQACRGGQL-GGVPVKDCVPESD---SWVHK---EKDFVCFMSTMPDVVAYRDEVKGSYFIS 352

  Fly   255 SLIRELNANGKKYDLLTLLTFVNQRVALDFESNVPATPMMDRQ-KQIPCL--TSMLTRILRF 313
            .::....::..|..::.|...|..|:..|        ....|| |.:||:  ||::.:...|
Zfish   353 YIVDVFCSSACKDHIMELFRKVAARMEKD--------ERFRRQAKLLPCIERTSLVKKFYLF 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	64/276 (23%)
caspbl	NP_001139064.1	Pyrin_ASC-like	5..84	CDD:260033
caspbl	NP_001139064.1	CASc	167..406	CDD:237997	62/254 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010