DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dcp-1 and casp22

DIOPT Version :9

Sequence 1:	NP_476974.1	Gene:	Dcp-1 / 37729	FlyBaseID:	FBgn0010501	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001313475.1	Gene:	casp22 / 561021	ZFINID:	ZDB-GENE-060526-186	Length:	376	Species:	Danio rerio

Alignment Length:	219	Identity:	85/219 - (38%)
Similarity:	120/219 - (54%)	Gaps:	10/219 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 SEYNMSHKHRGVALIFNHEFFDIPSLKSRTGTNVDAQELKKAFENLGFAVSVHKDCKLRDILKHV 133
            :||.|....||:.||||:|.|..|.:| |.|:.:|...||..||.|||:|.:.:| :....:|..
Zfish   121 NEYEMKSNPRGLCLIFNNENFKDPDMK-RHGSQMDTASLKDLFEWLGFSVEIKQD-QTVSAMKRT 183

  Fly   134 GKAAELDHTDNDCLAVAILSHG-EHGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPKLFFIQACQ 197
            .|....|....||....:|||| |.|.|.:.:....:|:|...|....|.|||||||:||||||:
Zfish   184 LKEYSEDRKHGDCFVCCVLSHGNESGVLGSDEKICPVDDITSPFNGANCSSLAGKPKVFFIQACR 248

  Fly   198 GDRLDGGITLEKGV----TETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGSWYMQSLIR 258
            |..:...:.:..|.    |:..|..|.|  ||..:|||.:.||:.||.|.|:..:|:|::|||..
Zfish   249 GHEIQSKVMVADGSGGSRTQKPGRVSVS--IPKDSDFLIARSTVEGYVSIRDRTSGTWFIQSLCE 311

  Fly   259 ELNANGKK-YDLLTLLTFVNQRVA 281
            .|....|: :|:|.:||.||..|:
Zfish   312 NLKEGSKRGHDILMILTKVNNDVS 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	84/217 (39%)
casp22	NP_001313475.1	CARD	3..88	CDD:279013
casp22	NP_001313475.1	CASc	123..366	CDD:237997	84/217 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810