DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dcp-1 and casp7

DIOPT Version :9

Sequence 1:	NP_476974.1	Gene:	Dcp-1 / 37729	FlyBaseID:	FBgn0010501	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001018443.1	Gene:	casp7 / 553634	ZFINID:	ZDB-GENE-050522-506	Length:	316	Species:	Danio rerio

Alignment Length:	249	Identity:	108/249 - (43%)
Similarity:	153/249 - (61%)	Gaps:	8/249 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 EYNMSHKHRGVALIFNHEFFDIPS-LKSRTGTNVDAQELKKAFENLGFAVSVHKDCKLRDILKHV 133
            :|.|||:..|..:|.|::.||..: :..|.||:.||.||.|.|::|||.|:|:.|...|::.:.:
Zfish    70 QYKMSHQRVGKCIIINNKNFDEKTGMNVRNGTDRDAGELFKCFKSLGFDVAVYNDQTCRNMERLL 134

  Fly   134 GKAAELDHTDNDCLAVAILSHGEHGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPKLFFIQACQG 198
            ...:|.||:|:.|.|..:|||||.|.:|..|....:..:...|....|.||.|||||||||||:|
Zfish   135 KAVSEEDHSDSSCFACILLSHGEEGMIYGTDGAMPIKTMTSLFKGDVCKSLVGKPKLFFIQACRG 199

  Fly   199 DRLDGGITLEKG----VTETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGSWYMQSLIRE 259
            ...|.|:..:.|    ..|||  ::..:|||:.|||||:|||:|||:||||...|||::|:|...
Zfish   200 SEFDDGVQTDSGPPNDTIETD--ANPRHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNV 262

  Fly   260 LNANGKKYDLLTLLTFVNQRVALDFESNVPATPMMDRQKQIPCLTSMLTRILRF 313
            |:..||:.:::.:||.||..||..||| ....|....:|||||:.||||:.|.|
Zfish   263 LSEFGKQLEIMQILTRVNYMVATSFES-WSEDPRFSEKKQIPCVVSMLTKELYF 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	107/246 (43%)
casp7	NP_001018443.1	CASc	71..315	CDD:237997	107/246 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580505
Domainoid	1	1.000	200	1.000	Domainoid score	I2984
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11168
Inparanoid	1	1.050	209	1.000	Inparanoid score	I3655
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	1	1.000	-	-		mtm6547
orthoMCL	1	0.900	-	-		OOG6_103710
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X460
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.700