DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dcp-1 and casp9

DIOPT Version :9

Sequence 1:	NP_476974.1	Gene:	Dcp-1 / 37729	FlyBaseID:	FBgn0010501	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001007405.2	Gene:	casp9 / 492763	ZFINID:	ZDB-GENE-030825-5	Length:	436	Species:	Danio rerio

Alignment Length:	314	Identity:	108/314 - (34%)
Similarity:	145/314 - (46%)	Gaps:	55/314 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 PESLVVGGATAASPLPANKFVARMPVERYASE--YNMSHKHRGVALIFNHEFFDIPS-LKSRTGT 100
            ||||.|....:    |.::.|.|....|..|.  |.|.....||.||.|:..|:..| |..|.|:
Zfish   134 PESLPVHKTYS----PPSETVVRPTRPRRDSIQCYKMDASPCGVCLIINNINFEKASELNDRKGS 194

  Fly   101 NVDAQELKKAFENLGFAVSVHKDCKLRDILKHVGKAAELDHTDNDCLAVAILSHGEH-------G 158
            |:|..:|:|.|:.|.|.|:|.::.|.:.|...:...|:.||:..||..|.|||||..       |
Zfish   195 NIDCDKLEKRFKALNFEVTVKRNLKSKRIRHEMASLAKKDHSTYDCCVVIILSHGTEASHNRFPG 259

  Fly   159 YLYAKD-TQYKLDNIWHYFTATFCPSLAGKPKLFFIQACQGDRLD--------------GGI--- 205
            .::..| ....:..|.:|.....||||.|||||||||||.|...|              |||
Zfish   260 AVHGVDGPAVPIQIITNYLNGQNCPSLQGKPKLFFIQACGGGEKDIGFEVSPDDVQPSIGGIDDE 324

  Fly   206 -----------TLEKGVTETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGSWYMQSLIRE 259
                       :|.....|.|..:|    :|..:|.|.||||.|||.|||:...||||:::|.|.
Zfish   325 MDAIPMSSSSDSLSTASDELDARAS----LPTPSDILVSYSTFPGYVSWRDTEAGSWYVENLDRV 385

  Fly   260 LNANGKKYDLLTLLTFVNQRVALDFESNVPATPMMDRQKQIPCLTSMLTRILRF 313
            |..|....||:|:|..||..|     |.:.|..:   .||:|...:.|.::|.|
Zfish   386 LEENAITDDLVTMLMLVNDAV-----SQISAKGL---YKQMPGSFNFLRKLLYF 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	97/278 (35%)
casp9	NP_001007405.2	CARD_CASP9	5..88	CDD:176740
casp9	NP_001007405.2	CASc	163..432	CDD:237997	98/281 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910