DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dcp-1 and Dronc

DIOPT Version :9

Sequence 1:	NP_476974.1	Gene:	Dcp-1 / 37729	FlyBaseID:	FBgn0010501	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_524017.1	Gene:	Dronc / 39173	FlyBaseID:	FBgn0026404	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	236	Identity:	62/236 - (26%)
Similarity:	106/236 - (44%)	Gaps:	31/236 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 YNM-SHKHRGVALIFNHEFFDIPSL-KSRTGTNVDAQELKKAFENLGFAV----SVHKDCKLRDI 129
            |.| |..:|||.|:.|  ..|.|.. :.|.|...|::.|...|:.|.|.:    :|::| :...:
  Fly   187 YKMQSRFNRGVLLMVN--IMDYPDQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQD-QFFKL 248

  Fly   130 LKHVGKAAELDHTDNDCLAVAILSH-----GEHGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPK 189
            |..|..::.:.:|  :|..:.:::|     |:....:...:...:..|..:|....||.|..|||
  Fly   249 LTMVTSSSYVQNT--ECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPK 311

  Fly   190 LFFIQACQGDRLDGGITLEKG---------------VTETDGESSTSYKIPIHADFLFSYSTIPG 239
            :.....|:||..|.|....:|               .|:|:|..|.|..:|..||.|..|:..||
  Fly   312 VLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPG 376

  Fly   240 YFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQRV 280
            |.:.|:::.||||:|...:.:..:....||..:|...::.|
  Fly   377 YVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAV 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	62/236 (26%)
Dronc	NP_524017.1	CARD	18..106	CDD:260018
Dronc	NP_524017.1	CASc	186..443	CDD:237997	62/236 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457286
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840