DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dcp-1 and cflara

DIOPT Version :9

Sequence 1:	NP_476974.1	Gene:	Dcp-1 / 37729	FlyBaseID:	FBgn0010501	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001300701.1	Gene:	cflara / 373114	ZFINID:	ZDB-GENE-030826-3	Length:	461	Species:	Danio rerio

Alignment Length:	270	Identity:	61/270 - (22%)
Similarity:	98/270 - (36%)	Gaps:	79/270 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 NKFVARMP------VERYASEYNMSHKHRGVALIFNHEFFDIPSLKSRTGTNVDAQELKKAFENL 114
            ||....:|      .:....||.|:.:.||:.:|.:             ....|.:.||..||.|
Zfish   220 NKLKLSVPETGIHYQQAITEEYQMNPEQRGLCVIID-------------CVGYDGEMLKHTFECL 271

  Fly   115 GFAVSVH------------KDCKLRDILKHVGKAAELDHTDNDCLAVAILSHGEHGYLYAKDTQ- 166
            ||.|..|            :|..|..||:.|           .|....::|.|.:.:|.|.|:.
Zfish   272 GFKVVFHSLLGLKETQKVLEDLSLNRILQRV-----------RCFVCCLISRGTNTHLLATDSNR 325

  Fly   167 --YKLDNIWHYFTATFCPSLAGKPKLFFIQACQGDRLDGGITLEKGVTETDG----ESSTSYKIP 225
              ..|.::...|.||.|      ||:||.|..:........:::....|||.    :.|.:..:|
Zfish   326 LGINLKDLKQLFNATKC------PKIFFTQLYRITEAPVMPSMDDEYLETDAPASRQCSNTGSVP 384

  Fly   226 IHADFLFSYSTIPGYFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQRVALDFESNVPA 290
            :.||.|:|..|                  :.::.|..:|.:...|..|   |..:....|.||
Zfish   385 MPADVLWSVCT------------------AEVKLLEESGHQSVYLNAL---NNALLKGHERNV-- 426

  Fly   291 TPMMDRQKQI 300
             |::|..|::
Zfish   427 -PILDVMKEV 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	57/249 (23%)
cflara	NP_001300701.1	DED	8..87	CDD:307481
		DED_c-FLIP_r2	100..180	CDD:260046
		CASc	241..461	CDD:320727	57/249 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810