DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dcp-1 and csp-1

DIOPT Version :9

Sequence 1:	NP_476974.1	Gene:	Dcp-1 / 37729	FlyBaseID:	FBgn0010501	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001022452.1	Gene:	csp-1 / 175007	WormBaseID:	WBGene00000819	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	341	Identity:	84/341 - (24%)
Similarity:	151/341 - (44%)	Gaps:	51/341 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TRNYGVGIRSPNGSENRGSFIMADNTDAKGCTPESLVVGGATAASPLPANKFVARMPVERYASEY 71
            |.|....|:.|:..|      ..|...:.|.:.:..::...|........:......:|.|.|:.
Worm   209 TENKDPNIQEPSPVE------FLDVQSSLGSSMKPPILDKPTKLDDPAETRHDCSYSLEEYDSQS 267

  Fly    72 NM--------SHKH----------RGVALIFNHEFFDIPSLKSRTGTNVDAQELKKAFENLGFAV 118
            .|        :|||          ||..||.::|.|  .:::.|.||..|...|.|.|:.|.:.|
Worm   268 RMPRTDAKKSNHKHKYCYEMNSNPRGTVLILSNENF--KNMERRVGTKQDEVNLTKLFQKLQYTV 330

  Fly   119 SVHKDCKLRDILKHVGKAAELDHTDNDCLAVAILSHGE-HGYLYAKDTQYKLDNIWHYFT-ATFC 181
            ...::.:...:|:.:.:.||:.|||:  :.:.:||||: .|.::..|....  |:....| ..:.
Worm   331 ICKRNLEAESMLEAIKEFAEMAHTDS--IILFLLSHGDGAGSVFGIDDMPV--NVMEVSTYLAYH 391

  Fly   182 PSLAGKPKLFFIQACQGDRLDGGITLEKGVTETDGESSTSYKI--------------PIHADFLF 232
            .:|..|||...:.||:|.:|:.|:.:: |:...:.:.:...|.              .::||.:.
Worm   392 QNLLLKPKWVAVSACRGGKLNMGVPVD-GLPALEDKCAPISKFWNLMMSRIMPGTFTSLNADVII 455

  Fly   233 SYSTIPGYFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQRVALDFESNVPATPMMDRQ 297
            |:||..|:.|:|:...|:||::|:.:..|.:.|...||.:||...:.|...:| ||....::
Worm   456 SFSTTDGFTSYRDEEAGTWYIKSMCKVFNKHSKTMHLLDILTETGRNVVTKYE-NVQGNVVL--- 516

  Fly   298 KQIPCLTSMLTRILRF 313
            ||.|.:.|.||:...|
Worm   517 KQAPEILSRLTKQWHF 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	72/275 (26%)
csp-1	NP_001022452.1	SPK	76..188	CDD:214732
csp-1	NP_001022452.1	CASc	285..533	CDD:214521	69/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	130	1.000	Domainoid score	I3239
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	1	1.000	-	-		mtm4766
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920