DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dcp-1 and Cflar

DIOPT Version :9

Sequence 1:	NP_476974.1	Gene:	Dcp-1 / 37729	FlyBaseID:	FBgn0010501	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001029036.1	Gene:	Cflar / 117279	RGDID:	620847	Length:	480	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	63/243 - (25%)
Similarity:	99/243 - (40%)	Gaps:	37/243 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 MPVERYASEYNMSHKHRGVALIFNHEFFDIPSLKSRTGTNVDAQELKKAFENLGFAVSVHKDCKL 126
            :|...:...|.|..|..|:.||.:             ....|.:.|::.|.:||:.|........
  Rat   240 LPPHIHEESYRMQSKPLGICLIID-------------CIGNDTEYLRETFTSLGYRVQPFLFPSS 291

  Fly   127 RDILKHVGKAAEL-DHTDNDCLAVAILSHGEHGYLYAKDTQY---KLDNIWHYFTATFCPSLAGK 187
            .:|.:.|.:.:.: .|.|.|.....::|.|....:...|..|   .|:|:...|....||||.||
  Rat   292 HEITQIVRRFSNMTQHQDYDSFVCVLVSRGGSQSMMGVDQVYSGFSLENVKDMFKGDMCPSLRGK 356

  Fly   188 PKLFFIQACQGDRLDGGITLEKGVTETDGES----STSYKIPIH------ADFLFSYSTIPGYFS 242
            |||||||..:        .||....|.||.:    ::.:..|.|      ||..:|..|......
  Rat   357 PKLFFIQNYE--------ALEDNSLEVDGPAIKNVNSRHLHPRHCTTHPDADIFWSLCTADVSRL 413

  Fly   243 WRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQRVALDFESNVPA 290
            .:..::.|.|:|.| .:|...|:|..|:.|...:..:| ..:.||||:
  Rat   414 EQPSSSLSVYLQKL-SQLLEQGRKRSLVDLHVELMDKV-YAWNSNVPS 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	62/234 (26%)
Cflar	NP_001029036.1	DED_c-FLIP_r1	6..85	CDD:260044
		DED_c-FLIP_r2	96..176	CDD:260046
		CASc	249..479	CDD:412128	62/234 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810