Protein Alignment CG33964 and mettl25

DIOPT Version :9

• Sequence 1: NP_001033941.1
• Gene: CG33964 / 3772719
• FlyBaseID: FBgn0053964
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_004912966.2
• Gene: mettl25 / 779563
• XenbaseID: XB-GENE-5864940
• Length: 584
• Species: Xenopus tropicalis
• Alignment Length: 611
• Identity: 174/611 - (28%)
• Similarity: 279/611 - (45%)
• Gaps: 153/611 - (25%)

  Fly     1 MSKVGVVQLQRRLDGLLAFLNPHWDFVNCHMVNYLTDQHWDGFLS---ETLKSEIA--------- 53
            :.:|...||:..:..||.||:........|.|::.|...|...::   ||:.|..:
 Frog     5 LCEVSTDQLKEAVKKLLQFLHETLQISGAHTVDFYTQDIWKKLVAVSPETVLSAFSKHNGTSHHI 69

  Fly    54 GKEDVALAIEDLFWKTDESERFPAWREFLGKSKQERLSLHPKLLTSVEELIEG----QGNSTQLS 114
            |||...|:  .:|    .:::......|:..|....| ::..:.|||:||:|.    :..|..|.
 Frog    70 GKEVPELS--SIF----SNQQLVNIEAFVEASHSHSL-VNMGICTSVDELLEALAVHKAGSPDLK 127

  Fly   115 IREFMSAKKCHEVDLTAVLVDQLVKNSGQDC---FIVDAGDGKGYLSSRLALQYGHRVLGIDANA 176
            ..:||:.||.|||    :::.|||::....|   .::|.|.|||||||.|:::|..:|.|||::.
 Frog   128 TDQFMNDKKSHEV----LIMSQLVQSIANICGVKQVIDLGAGKGYLSSYLSMKYNLKVYGIDSSD 188

  Fly   177 ANTENALNRNRKLQRAWNGL------------------------------TERAELQVQGITPK- 210
            .||:.|..||:||::.|...                              |:|...:.:...||
 Frog   189 TNTDGANRRNQKLKKYWKTYKTDAREVSKAQESDQNKDCLLPNYSCQEVNTDREIPKPKSCFPKL 253

  Fly   211 -----------------RRSKKSPAR-----ESTKSAPAL----------------------ENY 231
                             :|.:::..|     :|.:|:|.|                      |..
 Frog   254 EESSISNDLKSINVSEWKRDQENYQRTLQPADSDRSSPFLDILPADAVEEQTFSKSVHKSLSEQE 318

  Fly   232 KTTAKF--------------------ITTELNFGALLAENFTQFRPEDSPNICLTGLHTCGNLAA 276
            |...|.                    ||.|.....::         ||.....:.||||||:||.
 Frog   319 KEQRKMENISIKEQRGSRVYLPLTCKITVETELSEII---------EDLEESIMVGLHTCGDLAP 374

  Fly   277 TCLQVFHAQTDCRLLCNVGCCYHLLRERYSQQEFFGNKSLMELQ-TDYGFPLSQYLRERQVRMGR 340
            ..|::|.|:.:.:.:|:||||||||.|.:...|       .|:. |.:|||:|.:|:|.....||
 Frog   375 NTLRIFTAKPEIKAVCSVGCCYHLLSEEFESPE-------EEITVTTWGFPMSIHLKESSWFFGR 432

  Fly   341 NARMLAAQSIERTLDTKELPNVTLYYRALLEILVCRHAPELKNELQVGKV-RKFESFEEYIQKCA 404
            ||||.|..::||....:.|...:|:|||:|::::.......:::.:|||: .|..:|.||::|..
 Frog   433 NARMSACLALERVAVGQGLATESLFYRAVLQVILKDCFSVTQSDKRVGKIFSKSGNFTEYVRKSL 497

  Fly   405 TKL--DAPWLAAVEKEELQSLLQEYAVHKYFLDLFYLLRMSFAPVLESLILLDRLLYLKE---LG 464
            .||  |...|:.:   |:....::|...|..::.|.:|::..||.:|:||||||||||||   |.
 Frog   498 KKLGHDDSELSDM---EIMEYFEKYKPRKNEMEAFNMLKVLLAPCIEALILLDRLLYLKEQNNLA 559

  Fly   465 YERSYLIDLFDPVISPRHFAIVSIKQ 490
            :  |.|:.|||||.|||.:|:||:|:
 Frog   560 W--SGLVKLFDPVKSPRCYAVVSMKK 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33964	NP_001033941.1	Methyltransf_32	122..304	CDD:290402	70/279 (25%)
mettl25	XP_004912966.2	AdoMet_MTases	135..399	CDD:418430	68/276 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	89	1.000	Domainoid score	I7752
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32774
Inparanoid	1	1.050	209	1.000	Inparanoid score	I3587
OMA	1	1.010	-	-		QHG55767
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008296
OrthoInspector	1	1.000	-	-		oto104216
Panther	1	1.100	-	-	LDO	PTHR12496
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5160
SonicParanoid	1	1.000	-	-		X6279
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100