Protein Alignment CG33964 and Mettl25

DIOPT Version :10

• Sequence 1: NP_001033941.1
• Gene: CG33964 / 3772719
• FlyBaseID: FBgn0053964
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: XP_038935029.2
• Gene: Mettl25 / 314798
• RGDID: 1310270
• Length: 656
• Species: Rattus norvegicus
• Alignment Length: 627
• Identity: 174/627 - (27%)
• Similarity: 268/627 - (42%)
• Gaps: 167/627 - (26%)

  Fly     9 LQRRLDGLLAFLNPHWDFVNCHMVNYLTDQHWDGFLS-------ETLKSEIA----------GKE 56
            |...|..||:||.......:.|.|::.|...|...:.       .||:...|          |:.
  Rat    49 LHATLQDLLSFLRGALAISSAHTVDFYTKSIWQELVDLPPESVLATLRKSAAEAELHETLPLGEA 113

  Fly    57 DVALAIEDL---FWKTDESERFPAWREFLGKSKQ---ERLSL---HPKLLTSVEELIEGQGNSTQ 112
            :......||   |.:|  |::..:...|:..:|.   :.|.|   ..:|||::....| |.....
  Rat   114 EAGSGFIDLPKIFCET--SQKLLSVEAFVLTAKHYSVQNLGLCTPSEQLLTALRVNTE-QRTDEN 175

  Fly   113 LSIREFMSAKKCHEVDLTAVLVDQLVKNSG-------QDC---------------FIVDAGDGKG 155
            :...|||:.||.|||...:.|:..:....|       .:|               .|:|.|.|||
  Rat   176 VKAIEFMNTKKSHEVQAMSELICSIADYCGLKQSLRPGNCGRVRIPVRKSRETIVKIIDVGSGKG 240

  Fly   156 YLSSRLALQYGHRVLGIDANAANTENALNRNRKLQRAWN-------------------------- 194
            ||||.|:|:||..|.|||:::.||..|..|||||::.||
  Rat   241 YLSSFLSLKYGLNVYGIDSSSTNTHGAKERNRKLKKHWNLCHSQSRADSNGLVLKMPKESKVQSR 305

  Fly   195 ----GLTERAELQVQG-------------------ITPKRRSKKSPARESTK------------- 223
                |.:||.:...:|                   |..::|:..:...|..|
  Rat   306 SKCEGESERVQKSRRGDEDASAGVLADFSGSPVSVIRKQQRNLHAHPVEEEKLCCEDAFSLVDFL 370

  Fly   224 --------------SAPALEN--------------YKTTAKFITTELNFGALLAENFTQFRPEDS 260
                          .||.|..              |.....|||.:.....::         ||.
  Rat   371 PVDAIEPTSQVCHTEAPGLRKERGNATSKTRGSSIYSPLTSFITADTQLHDII---------EDL 426

  Fly   261 PNICLTGLHTCGNLAATCLQVFHAQTDCRLLCNVGCCYHLLRERYSQQEFFGNKSLMELQTDYGF 325
            .:..:.||||||:||...|::|.::.:.:.:|:||||||||.|.:..|    :|..  .:.::||
  Rat   427 EDCLMVGLHTCGDLAPNTLRIFASKAEVKGVCSVGCCYHLLSEEFENQ----HKGY--AKENWGF 485

  Fly   326 PLSQYLRERQVRMGRNARMLAAQSIERTLDTKELPNVTLYYRALLEILVCRHAPELKNELQVGKV 390
            |:..||:|.:...||||||.|..::||.:..:.||..:|:|||:|:.::.......|.|..|||:
  Rat   486 PMCHYLKEERWCCGRNARMSACLALERVVVGQGLPTESLFYRAVLQNIIKDCYGISKCEQYVGKI 550

  Fly   391 -RKFESFEEYIQKCATK--LDAPWLAAVEKEELQSLLQEYAVHKYFLDLFYLLRMSFAPVLESLI 452
             .|..||.||::....|  ||...::|   |.:....::|......|:.|.:|::..||.:|:||
  Rat   551 YSKCSSFLEYVRVSLKKLGLDESKISA---EIIMDYYEKYKPRMNELEAFNMLKVVLAPCIETLI 612

  Fly   453 LLDRLLYLKE---LGYERSYLIDLFDPVISPRHFAIVSIKQQ 491
            |||||.||||   :.:  |.|:.|||||.|||.:|::::|:|
  Rat   613 LLDRLCYLKEQEDIAW--SALVKLFDPVQSPRCYAVIALKKQ 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33964	NP_001033941.1	Methyltransf_32	122..304	CDD:379330	72/293 (25%)
Mettl25	XP_038935029.2	None