DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33964 and Rrnad1

DIOPT Version :9

Sequence 1:	NP_001033941.1	Gene:	CG33964 / 3772719	FlyBaseID:	FBgn0053964	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_705790.3	Gene:	Rrnad1 / 229503	MGIID:	2387197	Length:	475	Species:	Mus musculus

Alignment Length:	507	Identity:	136/507 - (26%)
Similarity:	218/507 - (42%)	Gaps:	87/507 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QLQRRLDGLLAFLNPHW-DFVNCHMVNYLTDQHWDGFLSETLKSEIAGKEDVALAIEDLFWKTD- 70
            ||...|..:||    |: ..::.:::.:.||..| |.|..:.:..:.|.....||...|....|
Mouse    16 QLAVDLTRVLA----HYRSILDAYIIEFFTDSLW-GTLPHSWQEALDGLNPPQLATLLLGMPRDG 75

  Fly    71 ESERF-PAWREFLGKSKQERLSL----HPKLLTSVEELIEGQGNSTQLS--IREFMSAKKCHEVD 128
            |..|: ..|...|...|....:|    .|...|. .|.:|....|::|:  .|:.:..||.||:.
Mouse    76 EEMRYRSVWPLTLLALKSTACALAFTRTPGFHTP-SEFLENPSQSSRLTAPFRKHVKPKKQHEIR 139

  Fly   129 LTAVLVDQLVKNSGQDCF-IVDAGDGKGYLSSRLALQYGHRVLGIDANAANTENALNRNRKLQRA 192
            ....||.:|...:|  |. :||.|.|:|:||..::|..|..|..::.|....:.|.:.:::|.:|
Mouse   140 RLGELVKKLSDLTG--CTQVVDVGSGQGHLSRFMSLGLGLMVKSLEGNQRLVKRAQHLDQELLKA 202

  Fly   193 WNGLTERAELQVQGITPKRRSKKSPARESTKSAPALENYKTTAKFITTELNFGALLAENFTQFRP 257
            .:.:.:|....||     |..:..|.......:|.     |..:.:...|.            ||
Mouse   203 LDKMEKRHPKMVQ-----RGPRHRPHHVVQWVSPT-----TLCEELLLPLE------------RP 245

  Fly   258 -EDSPNICLTGLHTCGNLAATCLQVFHAQTDCRLLCNVGCCYHLLRERYSQQEFFGNKSLMELQT 321
             :.|..:.|||||.||:|:...|:.|....:...|.:|||||                  |:|..
Mouse   246 GQSSARLLLTGLHACGDLSVALLRHFCCCPEVVALASVGCCY------------------MKLSD 292

  Fly   322 DYGFPLSQYL-----RERQVRMGRNARMLAAQSIERTLDTKELPNVTLYYRALLEILVCRHAPEL 381
            ...:||||::     .|...|: |.....|.:.....|...|....|..:||.||.::.:..|||
Mouse   293 PGSYPLSQWIAGLPGHELPYRL-REGACHALEDYAERLHKAEPGLQTHCFRAALETVIRQVCPEL 356

  Fly   382 KNELQVGKVRKFE-SFEEYIQKCATK--------LDAPWLAAVEKEELQSLLQEYAVHKYFLDLF 437
            :.....|..|..| ..|||:::...:        ||   |||         ||.:...:..:..|
Mouse   357 RRPGVQGIPRVHELKIEEYVKQGLKRVGLDPQLPLD---LAA---------LQAHQAQENRVVAF 409

  Fly   438 YLLRMSFAPVLESLILLDRLLYLKELGYERSYLIDLFDPVISPRHFAIVSIK 489
            :.|.:..||::|:||||||:|||:|.|: .:.|:.:|.|.:|||:..:|:.|
Mouse   410 FSLALLLAPLVETLILLDRMLYLQEQGF-YAELLPIFSPELSPRNLVLVATK 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33964	NP_001033941.1	Methyltransf_32	122..304	CDD:290402	50/183 (27%)
Rrnad1	NP_705790.3	Methyltransf_32	133..293	CDD:290402	52/201 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2651
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5160
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840