Protein Alignment wmd and TIF34

DIOPT Version :10

• Sequence 1: NP_611804.1
• Gene: wmd / 37727
• FlyBaseID: FBgn0034876
• Length: 328
• Species: Drosophila melanogaster
• Sequence 2: NP_013866.1
• Gene: TIF34 / 855177
• SGDID: S000004754
• Length: 347
• Species: Saccharomyces cerevisiae
• Alignment Length: 326
• Identity: 81/326 - (24%)
• Similarity: 145/326 - (44%)
• Gaps: 43/326 - (13%)

  Fly     6 LRQIPLTCSGHTRPVVHLDFSDICDAGYFLISACKDGSPMLRHGDTGDWVGTFEGHKGAVWNATL 70
            ::.|.||  ||.||:..:.::   ..|..|.|..||.|..:.:...|:.:||.:||.|.:|:..:
Yeast     1 MKAIKLT--GHERPLTQVKYN---KEGDLLFSCSKDSSASVWYSLNGERLGTLDGHTGTIWSIDV 60

  Fly    71 NRNATLAASGAADFTGKVWNAVTGAEIHSFQHKHIVKSVAFDRDS-------ENIVTGSNEKLVR 128
            :.......:|:||::.|:|:...|..:.:::....||.|.|....       :|::  .|...:.
Yeast    61 DCFTKYCVTGSADYSIKLWDVSNGQCVATWKSPVPVKRVEFSPCGNYFLAILDNVM--KNPGSIN 123

  Fly   129 VFNLEQPEAQPE----------EYAGHTG--AIKRALFCRGDKCIISAAEDKTVRLWDRMTGIE- 180
            ::.:|:..|..|          :...|.|  |...|.:....|.||:..:|..:..:|.....|
Yeast   124 IYEIERDSATHELTKVSEEPIHKIITHEGLDAATVAGWSTKGKYIIAGHKDGKISKYDVSNNYEY 188

  Fly   181 VQRLQFNSNP-NSLEISSD-NHILTISHGSSISFWEIDTLKKLKEVKVPTNVASASLHPDKHVFV 243
            |..:..:... :.::.|.| .:.:|.|..::....::.||:.||:.:....:.:|.:.|.|...:
Yeast   189 VDSIDLHEKSISDMQFSPDLTYFITSSRDTNSFLVDVSTLQVLKKYETDCPLNTAVITPLKEFII 253

  Fly   244 CGGED--------------FKMYKFDYITGNEIESFKGHFGPVHSVKFSPDGELYASGSEDGTLR 294
            .||..              |:...:..|...||...:|||||:::|..||.|..||||.|||.:|
Yeast   254 LGGGQEAKDVTTTSANEGKFEARFYHKIFEEEIGRVQGHFGPLNTVAISPQGTSYASGGEDGFIR 318

  Fly   295 L 295
            |
Yeast   319 L 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wmd	NP_611804.1	WD40	<7..299	CDD:441893	81/325 (25%)
		WD40 repeat	25..60	CDD:293791	9/34 (26%)
		WD40 repeat	66..101	CDD:293791	7/34 (21%)
		WD40 repeat	108..144	CDD:293791	7/52 (13%)
		WD40 repeat	150..186	CDD:293791	8/36 (22%)
		WD40 repeat	190..225	CDD:293791	8/36 (22%)
		WD40 repeat	231..266	CDD:293791	9/48 (19%)
		WD40 repeat	272..308	CDD:293791	13/24 (54%)
TIF34	NP_013866.1	WD40	<6..319	CDD:441893	78/319 (24%)
		WD40 repeat	13..49	CDD:293791	9/38 (24%)
		WD40 repeat	56..91	CDD:293791	7/34 (21%)
		WD40 repeat	96..148	CDD:293791	9/53 (17%)
		WD40 repeat	156..193	CDD:293791	8/36 (22%)
		WD40 repeat	240..290	CDD:293791	9/49 (18%)
		WD40 repeat	297..319	CDD:293791	11/21 (52%)