DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wmd and AT1G15470

DIOPT Version :9

Sequence 1:	NP_001097436.1	Gene:	wmd / 37727	FlyBaseID:	FBgn0034876	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_563978.1	Gene:	AT1G15470 / 838117	AraportID:	AT1G15470	Length:	333	Species:	Arabidopsis thaliana

Alignment Length:	318	Identity:	149/318 - (46%)
Similarity:	205/318 - (64%)	Gaps:	22/318 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PLTCSGHTRPVVHLDFSDICDAGYFLISACKDGSPMLRHGDTGDWVGTFEGHKGAVWNATLNRNA 74
            ||.|.||:||||.:.:|.:...|:|||||.||.:||||:|:||||:|||||||||||:.:|::||
plant     4 PLVCHGHSRPVVDVAYSPVTPDGFFLISASKDSNPMLRNGETGDWIGTFEGHKGAVWSCSLDKNA 68

  Fly    75 TLAASGAADFTGKVWNAVTGAEIHSFQHKHIVKSVAFDRDSENIVTGSNEKLVRVFNLEQPEAQP 139
            ..|||.:||||.|:|||:||.|:|||:|||||::.||..|:..::||..||::|:|:|.:|:|.|
plant    69 IRAASASADFTAKIWNALTGDELHSFEHKHIVRACAFSEDTHRLLTGGMEKILRIFDLNRPDAPP 133

  Fly   140 EEYAGHTGAIKRALFCRGDKCIISAAEDK-TVRLWDRMTGIEVQRLQFNSNPNSLEISSDNHILT 203
            :|.....|:|:...:...|..|:|:..|. .:||||..:...|..|:..|...|.|:|.|...:|
plant   134 KEVGNSPGSIRTVEWLHSDNTILSSCTDTGDIRLWDIRSDKIVHTLETKSPVTSAEVSQDGRYIT 198

  Fly   204 ISHGSSISFWEIDTLKKLKEVKVPTNVASASLHPDKH--VFVCGGEDFKMYKFDYITGNEIESFK 266
            .:.|||:.||:......||...:|.||.||||.| ||  .|:.||||..:::||:.||.||...|
plant   199 TADGSSVKFWDAKNFGLLKSYDMPCNVESASLEP-KHGNTFIAGGEDMWVHRFDFQTGEEIGCNK 262

  Fly   267 GHFGPVHSVKFSPDGELYASGSEDGTLRLWQTTVGKTYGLWKCTEPADLGNSISSPRE 324
            ||.||||.|:::|.||.|.|||||||:|:|  .||                |::.|.|
plant   263 GHHGPVHCVRYAPGGESYTSGSEDGTVRIW--VVG----------------SVNHPEE 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wmd	NP_001097436.1	WD40	12..297	CDD:238121	141/287 (49%)
		WD40 repeat	25..60	CDD:293791	21/34 (62%)
		WD40 repeat	66..101	CDD:293791	20/34 (59%)
		WD40 repeat	108..144	CDD:293791	14/35 (40%)
		WD40 repeat	150..186	CDD:293791	10/36 (28%)
		WD40 repeat	190..225	CDD:293791	12/34 (35%)
		WD40 repeat	231..266	CDD:293791	18/36 (50%)
		WD40 repeat	272..308	CDD:293791	18/35 (51%)
AT1G15470	NP_563978.1	WD40	9..292	CDD:238121	140/283 (49%)
		WD40 repeat	15..54	CDD:293791	22/38 (58%)
		WD40 repeat	101..138	CDD:293791	14/36 (39%)
		WD40 repeat	143..180	CDD:293791	10/36 (28%)
		WD40 repeat	186..220	CDD:293791	12/33 (36%)
		WD40 repeat	225..262	CDD:293791	19/37 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	66	1.000	Domainoid score	I3559
eggNOG	1	0.900	-	-		E1_KOG0278
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H43881
Inparanoid	1	1.050	304	1.000	Inparanoid score	I766
OMA	1	1.010	-	-		QHG53528
OrthoDB	1	1.010	-	-		D1239790at2759
OrthoFinder	1	1.000	-	-		FOG0005164
OrthoInspector	1	1.000	-	-		otm2547
orthoMCL	1	0.900	-	-		OOG6_103369
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3682
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.740