Protein Alignment wmd and Eif3i

DIOPT Version :10

• Sequence 1: NP_611804.1
• Gene: wmd / 37727
• FlyBaseID: FBgn0034876
• Length: 328
• Species: Drosophila melanogaster
• Sequence 2: NP_061269.1
• Gene: Eif3i / 54709
• MGIID: 1860763
• Length: 325
• Species: Mus musculus
• Alignment Length: 313
• Identity: 82/313 - (26%)
• Similarity: 143/313 - (45%)
• Gaps: 31/313 - (9%)

  Fly    10 PLTCSGHTRPVVHLDFSDICDAGYFLISACKDGSPMLRHGDTGDWVGTFEGHKGAVWNATLNRNA 74
            |:...||.|.:..:.::   ..|..|.:..||....:.:...|:.:||:.||.||||....:.:.
Mouse     3 PILLQGHERSITQIKYN---REGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDT 64

  Fly    75 TLAASGAADFTGKVWNAVTGAEIHSFQHKHIVKSVAFDRDSENIVTGSNEK------LVRVFNLE 133
            ....:|:||.:.::|:..||.::...:....|::..||... ||:..|.:|      .|..|:|.
Mouse    65 KHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGG-NIIMFSTDKQMGYQCFVSFFDLR 128

  Fly   134 QPEA--QPEEYAG---HTGAIKRALFCRGDKCIISAAEDKTVRLWDRMTG-IEVQRLQFNSNPNS 192
            .|..  ..|.|..   :...|..|::....:|:|:..|...:..:...:| :.|...:.:...|.
Mouse   129 DPSQIDSNEPYMKIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVLVNVKEHSRQIND 193

  Fly   193 LEISSD-NHILTISHGSSISFWEIDTLKKLKEVKVPTNVASASLHPD-KHVFVCGGED------- 248
            :::|.| ...:|.|..::...::..||:..|..:....|.||:|.|: .||.:.||::
Mouse   194 IQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTT 258

  Fly   249 ------FKMYKFDYITGNEIESFKGHFGPVHSVKFSPDGELYASGSEDGTLRL 295
                  |:...|......|....||||||::||.|.|||:.|:||.|||.:|:
Mouse   259 STRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wmd	NP_611804.1	WD40	<7..299	CDD:441893	82/313 (26%)
		WD40 repeat	25..60	CDD:293791	7/34 (21%)
		WD40 repeat	66..101	CDD:293791	7/34 (21%)
		WD40 repeat	108..144	CDD:293791	12/43 (28%)
		WD40 repeat	150..186	CDD:293791	6/36 (17%)
		WD40 repeat	190..225	CDD:293791	8/35 (23%)
		WD40 repeat	231..266	CDD:293791	11/48 (23%)
		WD40 repeat	272..308	CDD:293791	13/24 (54%)
Eif3i	NP_061269.1	WD40	<5..311	CDD:441893	80/309 (26%)
		WD 1	8..47		8/41 (20%)
		WD40 repeat	14..50	CDD:293791	7/38 (18%)
		WD 2	50..91		12/40 (30%)
		WD40 repeat	55..91	CDD:293791	8/35 (23%)
		WD 3	144..183		6/38 (16%)
		WD40 repeat	150..185	CDD:293791	6/34 (18%)
		WD 4	186..225		7/38 (18%)
		WD40 repeat	191..224	CDD:293791	7/32 (22%)
		WD40 repeat	232..272	CDD:293791	11/39 (28%)
		WD 5	283..324		18/29 (62%)
		WD40 repeat	288..311	CDD:293791	12/22 (55%)