DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wmd and CG7568

DIOPT Version :9

Sequence 1:	NP_001097436.1	Gene:	wmd / 37727	FlyBaseID:	FBgn0034876	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_001263071.1	Gene:	CG7568 / 43482	FlyBaseID:	FBgn0039673	Length:	482	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	71/314 - (22%)
Similarity:	138/314 - (43%)	Gaps:	53/314 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QIPLTCSGHTRPVVHLDFSDICDAGYFLISACKDGSPMLRHGDTGDWVGTFEGHKGAVWNATLNR 72
            |:....|||...|..:.|    :..::|:        .|:.|.:|:.:.||    ..:::..:
  Fly   151 QVEHILSGHDNVVFSVGF----NFPHWLV--------YLQSGGSGNNLTTF----SIIFSDKI-- 197

  Fly    73 NATLAASGAADFTGKVWNAVTGAEIHSFQHKHIVKSVAFD---RDSENIVTGSNEKLVRVFNLEQ 134
                 .:|:.|.|.|||:|.:|..:.:| :.|..:.||.:   .|.::|.|.|.:...|::::|.
  Fly   198 -----VTGSFDGTAKVWSATSGQSLCTF-YGHTAELVAAEFHPVDGKSIATASLDGSARIYDVET 256

  Fly   135 PEAQPEEYAGHTGAIKRALFCRGDKCIISAAEDKTVRLWDRMTGIEVQRLQFNSNPNSLEISSDN 199
            .. :.::...|...:..|.|.|..:.:::.:.|.:..:||    :..:.|......:|.|:|  |
  Fly   257 SH-ELQQLTHHGAEVIAARFNRDGQMLLTGSFDHSAAIWD----VRSKSLGHQLRGHSAELS--N 314

  Fly   200 HILTISHGSSISFWEIDTLKKLKEV-KVPTNVASASLHPDKHVFV-----------CGGE-DFKM 251
            .:...| ||.|:...:|...::.:. |:...:..|:.|.|:.:.|           |..: ..::
  Fly   315 CVWNFS-GSLIATGSLDNTARIWDTRKLDQELYLAARHSDEVLDVSFDAAGQLLATCSSDCTARV 378

  Fly   252 YKFDYITGNEIESFK---GHFGPVHSVKFSPDGELYASGSEDGTLRLWQTTVGK 302
            ::.:  ..:|:|...   ||...|..|.|||.|.:..:.|.|.|.|||.|..|:
  Fly   379 WRLE--GSSELEMLSLMAGHSDEVSKVCFSPSGCMLLTASADNTARLWLTESGQ 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wmd	NP_001097436.1	WD40	12..297	CDD:238121	67/303 (22%)
		WD40 repeat	25..60	CDD:293791	7/34 (21%)
		WD40 repeat	66..101	CDD:293791	8/34 (24%)
		WD40 repeat	108..144	CDD:293791	8/38 (21%)
		WD40 repeat	150..186	CDD:293791	7/35 (20%)
		WD40 repeat	190..225	CDD:293791	9/35 (26%)
		WD40 repeat	231..266	CDD:293791	7/46 (15%)
		WD40 repeat	272..308	CDD:293791	14/31 (45%)
CG7568	NP_001263071.1	WD40	93..466	CDD:225201	71/314 (23%)
		WD40 repeat	122..158	CDD:293791	1/6 (17%)
		WD40	154..467	CDD:238121	70/311 (23%)
		WD40 repeat	189..222	CDD:293791	10/44 (23%)
		WD40 repeat	228..265	CDD:293791	8/37 (22%)
		WD40 repeat	270..306	CDD:293791	7/39 (18%)
		WD40 repeat	314..348	CDD:293791	7/34 (21%)
		WD40 repeat	355..393	CDD:293791	4/39 (10%)
		WD40 repeat	400..436	CDD:293791	14/31 (45%)
		WD40 repeat	442..466	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR44156
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100