Protein Alignment wmd and STRAP

DIOPT Version :10

• Sequence 1: NP_611804.1
• Gene: wmd / 37727
• FlyBaseID: FBgn0034876
• Length: 328
• Species: Drosophila melanogaster
• Sequence 2: NP_009109.3
• Gene: STRAP / 11171
• HGNCID: 30796
• Length: 350
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 193/318 - (60%)
• Similarity: 243/318 - (76%)
• Gaps: 1/318 - (0%)

  Fly     6 LRQIPLTCSGHTRPVVHLDFSDICDAGYFLISACKDGSPMLRHGDTGDWVGTFEGHKGAVWNATL 70
            :||.||||||||||||.|.||.|...|||||||||||.||||.||||||:|||.|||||||.|||
Human     3 MRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATL 67

  Fly    71 NRNATLAASGAADFTGKVWNAVTGAEIHSFQHKHIVKSVAFDRDSENIVTGSNEKLVRVFNLEQP 135
            |::||.||:.|||||.|||:||:|.|:.:..||||||:|.|.:||..::||..:||:|:::|.:|
Human    68 NKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKP 132

  Fly   136 EAQPEEYAGHTGAIKRALFCRGDKCIISAAEDKTVRLWDRMTGIEVQRLQFNSNPNSLEISSDNH 200
            ||:|:|.:|||..||:||:|..||.|:| |:||||||||..|..||:.|.||.:.:|:|...:..
Human   133 EAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGE 196

  Fly   201 ILTISHGSSISFWEIDTLKKLKEVKVPTNVASASLHPDKHVFVCGGEDFKMYKFDYITGNEIESF 265
            ||.|::|.||:|....:|..:|..:.|..:.||||||:|...|.||||||:||:||.:|.|:||:
Human   197 ILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESY 261

  Fly   266 KGHFGPVHSVKFSPDGELYASGSEDGTLRLWQTTVGKTYGLWKCTEPADLGNSISSPR 323
            ||||||:|.|:||||||||||||||||||||||.||||||||||..|.:....::.|:
Human   262 KGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPK 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wmd	NP_611804.1	WD40	<7..299	CDD:441893	180/291 (62%)
		WD40 repeat	25..60	CDD:293791	27/34 (79%)
		WD40 repeat	66..101	CDD:293791	21/34 (62%)
		WD40 repeat	108..144	CDD:293791	15/35 (43%)
		WD40 repeat	150..186	CDD:293791	21/35 (60%)
		WD40 repeat	190..225	CDD:293791	11/34 (32%)
		WD40 repeat	231..266	CDD:293791	22/34 (65%)
		WD40 repeat	272..308	CDD:293791	31/35 (89%)
STRAP	NP_009109.3	WD40	<4..294	CDD:441893	179/290 (62%)
		WD 1	12..56		34/43 (79%)
		WD 2	57..96		27/38 (71%)
		WD 3	98..137		19/38 (50%)
		WD40 repeat	104..141	CDD:293791	16/36 (44%)
		WD 4	141..179		24/38 (63%)
		WD40 repeat	146..181	CDD:293791	21/35 (60%)
		WD 5	180..212		12/31 (39%)
		WD40 repeat	187..221	CDD:293791	11/33 (33%)
		WD 6	221..262		23/40 (58%)
		WD40 repeat	226..262	CDD:293791	22/35 (63%)
		WD 7	263..302		34/38 (89%)