Protein Alignment Menl-2 and MAE1

DIOPT Version :10

• Sequence 1: NP_001027424.2
• Gene: Menl-2 / 3772692
• FlyBaseID: FBgn0029153
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_012896.1
• Gene: MAE1 / 853839
• SGDID: S000001512
• Length: 669
• Species: Saccharomyces cerevisiae
• Alignment Length: 561
• Identity: 188/561 - (33%)
• Similarity: 306/561 - (54%)
• Gaps: 35/561 - (6%)

  Fly    47 YNKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTDIARFTYLSAVHHRHRRLYYR 111
            :|||.|||.:||:...:..|:|..|.::|:|:..:........|.:|:..:::::..:::.||:.
Yeast   109 FNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLYFA 173

  Fly   112 FIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNW-VDEGVKAICVTD 175
            .|:.:|::.:||:||||.||.:|.|...|::...:|:.|.:...|...:..: .|:.|..|.|:|
Yeast   174 LIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSIECRLATYGGDKDVDYIVVSD 238

  Fly   176 GGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDNQALLQDPLYVGARIPRVK 240
            ...:||:||.|...:.|::.|:.|.|..|.|.|..::||||||||:|:.|.:|.||:|.:..|::
Yeast   239 SEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLPVCLDVGTNNKKLARDELYMGNKFSRIR 303

  Fly   241 GPEYDELVDEFMESAVKCFGNNTFIHFEDFATPNALKFLEKYQYKYCCFNDDIQGTGATGLAAFI 305
            |.:||:.:::|:: |||....:..:|||||...||.:.||||:|:...||||||||||..:|:.|
Yeast   304 GKQYDDFLEKFIK-AVKKVYPSAVLHFEDFGVKNARRLLEKYRYELPSFNDDIQGTGAVVMASLI 367

  Fly   306 NVERITGRKLEDTVFLFVGAGSAALGIANMLAMELEVRGIPAEEATKNIYLMDVNG-ILTPESPN 369
            ...:.|.|.|:||..|..|||||.||||:.:...:...|:..|||.|.|:|||..| ||.....|
Yeast   368 AALKHTNRDLKDTRVLIYGAGSAGLGIADQIVNHMVTHGVDKEEARKKIFLMDRRGLILQSYEAN 432

  Fly   370 PPEMGKIFIKSMEP-----MKDMMAVLKKLKPSVLVGATGVGGIFNEEVLKTMAKNHERPAVFPL 429
            ......::.||...     .:.:..|::.:||:.|||.:...|.|.::|::.|.|::.||.:|||
Yeast   433 STPAQHVYAKSDAEWAGINTRSLHDVVENVKPTCLVGCSTQAGAFTQDVVEEMHKHNPRPIIFPL 497

  Fly   430 SNPTANSECTAEQAFTHTEGRVLFGSGSPFPPVVINGKRYRPAQANNCLTFPGIALAAITAKARY 494
            ||||...|.........|....|..:|||||||  :|  ||.::.|||.:||||.|.|:.::|..
Yeast   498 SNPTRLHEAVPADLMKWTNNNALVATGSPFPPV--DG--YRISENNNCYSFPGIGLGAVLSRATT 558

  Fly   495 LPNEVFSVVSHELARNTPQELLDEGT----LFPPIKDAHNVAFNVGVAMTQYLIDNDLSNV---- 551
            :.:::.|....:||..:|   |.||.    |.|.:....|.:..:..|:....::...:.:
Yeast   559 ITDKMISAAVDQLAELSP---LREGDSRPGLLPGLDTITNTSARLATAVILQALEEGTARIEQEQ 620

  Fly   552 -----------YPKPDDIC-EFVKRSLYKFDYRNSLPTTWD 580
                       .|:..|.| ::||..:::..||..:....|
Yeast   621 VPGGAPGETVKVPRDFDECLQWVKAQMWEPVYRPMIKVQHD 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	186/552 (34%)
MAE1	NP_012896.1	PRK13529	91..658	CDD:237414	187/556 (34%)