Protein Alignment Menl-2 and me1

DIOPT Version :10

• Sequence 1: NP_001027424.2
• Gene: Menl-2 / 3772692
• FlyBaseID: FBgn0029153
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001296966.1
• Gene: me1 / 768196
• ZFINID: ZDB-GENE-061013-438
• Length: 574
• Species: Danio rerio
• Alignment Length: 545
• Identity: 223/545 - (40%)
• Similarity: 336/545 - (61%)
• Gaps: 1/545 - (0%)

  Fly    39 WHVVMNGKYNKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTDIARFTYLSAVHH 103
            :.|..|...|||:||:::||.:|||.||:|....|.|.|:...|.::|....|:.|:.:|..:..
Zfish    19 YDVTRNPHLNKGMAFSLEERLQLGIHGLLPPCFLSQDVQVLRVLRSYELLKEDLDRYVFLMGLQD 83

  Fly   104 RHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNWVDEGV 168
            |:.:|:||.:..:||:.:|||||||||.....|||.|::...|||:|||:.||..|:.:|.::.:
Zfish    84 RNEKLFYRVLTSDIERFMPIVYTPTVGLACQQYGLTFRRPRGLFITIHDRSHIPTLLQSWPEKDI 148

  Fly   169 KAICVTDGGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDNQALLQDPLYVG 233
            :|:.||||.|:|||||:|...|||.:||:.||||.|.:||...:||.||||||.:.||:||||:|
Zfish   149 RAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGMPPQQCLPVMLDVGTDKEELLKDPLYIG 213

  Fly   234 ARIPRVKGPEYDELVDEFMESAVKCFGNNTFIHFEDFATPNALKFLEKYQYKYCCFNDDIQGTGA 298
            .|..||:|..||||:||||::....:|....|.|||||..||.:.|.||:.||..||||||||.|
Zfish   214 LRHKRVRGQAYDELLDEFMKAITDRYGMKCLIQFEDFANINAFRLLSKYRNKYLTFNDDIQGTAA 278

  Fly   299 TGLAAFINVERITGRKLEDTVFLFVGAGSAALGIANMLAMELEVRGIPAEEATKNIYLMDVNGIL 363
            ..:|..:...|||..|:.|...:|.|||.||:||..::.|.:|..|:|.|:..|.|:::|..|::
Zfish   279 VAVAGLLAALRITKSKMCDHTIVFQGAGEAAMGIGELIVMAMEKEGLPREQCIKKIWMVDSKGLI 343

  Fly   364 TPESPNPPEMGKIFIKSMEPMKDMMAVLKKLKPSVLVGATGVGGIFNEEVLKTMAKNHERPAVFP 428
            .....:.....:.|......||.:..|:|:|||:.::|...:.|.|.||::|.||..::.|.:|.
Zfish   344 VKGRDHLTHEKERFAHEHAQMKKLEDVVKELKPTAIIGVAAIAGAFTEEIIKAMASFNKNPIIFA 408

  Fly   429 LSNPTANSECTAEQAFTHTEGRVLFGSGSPFPPVVI-NGKRYRPAQANNCLTFPGIALAAITAKA 492
            |||||:.:||||||.:|.||||.:|.|||||.||.: :|:::.|.|.||...|||:.|.....:.
Zfish   409 LSNPTSKAECTAEQCYTLTEGRGIFASGSPFDPVTLPDGRKFYPGQGNNSYVFPGVGLGVTACEM 473

  Fly   493 RYLPNEVFSVVSHELARNTPQELLDEGTLFPPIKDAHNVAFNVGVAMTQYLIDNDLSNVYPKPDD 557
            |::|.:||.|.:..:|.....:.|.||.|:||:.....|:..:.|.:.:|...:.::.::|:|.|
Zfish   474 RHIPEDVFLVTAEAIAELVTDKDLAEGRLYPPLSSIREVSIKLAVKIVEYAYKHKMATLHPEPQD 538

  Fly   558 ICEFVKRSLYKFDYRNSLPTTWDYP 582
            ...|::..:|..||:.....::.:|
Zfish   539 KDAFIRSLIYSTDYQEFAVDSYSWP 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	222/534 (42%)
me1	NP_001296966.1	PLN03129	4..552	CDD:215594	220/532 (41%)