Protein Alignment Menl-2 and me2

DIOPT Version :10

• Sequence 1: NP_001027424.2
• Gene: Menl-2 / 3772692
• FlyBaseID: FBgn0029153
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001015690.1
• Gene: me2 / 548395
• XenbaseID: XB-GENE-943055
• Length: 583
• Species: Xenopus tropicalis
• Alignment Length: 586
• Identity: 228/586 - (38%)
• Similarity: 344/586 - (58%)
• Gaps: 30/586 - (5%)

  Fly    10 LRLASRPLLSSSRRFSVYDDEMEQITRPDWHVVMNGKYNKGLAFTIKERQRLGIMGLMPCSVRSM 74
            ||:.:||.:...|.....|....        :::|.:.|||:|||::|||.||:.||:|..|.|.
 Frog     5 LRVLARPCMVGCRAVHTKDKGKA--------LLLNPRTNKGMAFTLQERQILGLQGLLPPKVESQ 61

  Fly    75 DDQMNAALANFEARPTDIARFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLN 139
            |.|......|.......:.::.|:..:..|:.:|:||.:.::||..:|||||||||...:.||..
 Frog    62 DIQAARFHRNLSKMEDPLQKYIYIMGIQERNEKLFYRILLDDIEHLMPIVYTPTVGLACSQYGHT 126

  Fly   140 FQQAISLFISIHDKGHIRDLMHNWVDEGVKAICVTDGGRVLGLGDMGANAMGISLGKMILYTALG 204
            |::...|:|||.|:||||.::.:|.:..|||:.||||.|:||||::|...|||.:||:.||||..
 Frog   127 FRRPKGLYISILDRGHIRSILDHWPETDVKAVVVTDGERILGLGNLGVYGMGIPVGKLCLYTACA 191

  Fly   205 SIPPSTLMPVCLDVGTDNQALLQDPLYVGARIPRVKGPEYDELVDEFMESAVKCFGNNTFIHFED 269
            .|.|...:||.:||||||..||:||.|:|....|.:...||:|:||||::....:|.||.|.|||
 Frog   192 GIRPQKCLPVVIDVGTDNPTLLKDPFYMGLYQKRDRTQLYDDLIDEFMDAVTDRYGQNTLIQFED 256

  Fly   270 FATPNALKFLEKYQYKYCCFNDDIQGTGATGLAAFINVERITGRKLEDTVFLFVGAGSAALGIAN 334
            |...||.:||.||:.|||.||||||||.:..||..:..::..|:.:.:...||:|||.|||||||
 Frog   257 FGNHNAFRFLRKYREKYCTFNDDIQGTASVALAGMLAAQKAIGKPITEHKILFLGAGEAALGIAN 321

  Fly   335 MLAMELEVRGIPAEEATKNIYLMDVNGIL----------TPES--PNPPEMGKIFIKSMEPMKDM 387
            ::.|.:...||.||.|.:.|::.|..|:|          ..||  .:.||         :.:...
 Frog   322 LIVMSMMENGISAEAARERIWMFDKFGLLIQGRGEGIDSNQESFAHSAPE---------QAVGSF 377

  Fly   388 MAVLKKLKPSVLVGATGVGGIFNEEVLKTMAKNHERPAVFPLSNPTANSECTAEQAFTHTEGRVL 452
            :..:|.|:|:.::|..|.|.:|.|:|:|.||..:|||.:|.|||||..:|||||:|:|.|||:.|
 Frog   378 LDAVKVLQPTAIIGVAGAGKLFTEDVIKEMASINERPIIFALSNPTVKAECTAEEAYTWTEGQCL 442

  Fly   453 FGSGSPFPPVVI-NGKRYRPAQANNCLTFPGIALAAITAKARYLPNEVFSVVSHELARNTPQELL 516
            |.|||||..|.: :|:.::|.|.||...|||:|||.|.:..|::.:.||...:..||.....|.|
 Frog   443 FASGSPFDTVTLSDGRSFKPGQGNNAYIFPGVALAVILSGVRHISDRVFLEAAKALAEQLTAEEL 507

  Fly   517 DEGTLFPPIKDAHNVAFNVGVAMTQYLIDNDLSNVYPKPDDICEFVKRSLYKFDYRNSLPTTWDY 581
            .:|.|:||:.:...|:..:.|.:.:::..|.::..||:|.....:::..::..||.:..|..:|:
 Frog   508 GQGRLYPPLSNIREVSICIAVKVMEFVYRNGMAFQYPEPVGKNAYIRSKVWSTDYDSFPPDVYDW 572

  Fly   582 P 582
            |
 Frog   573 P 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	225/575 (39%)
me2	NP_001015690.1	PLN03129	25..565	CDD:215594	219/556 (39%)