Protein Alignment Menl-2 and me2

DIOPT Version :10

• Sequence 1: NP_001027424.2
• Gene: Menl-2 / 3772692
• FlyBaseID: FBgn0029153
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001003627.2
• Gene: me2 / 445233
• ZFINID: ZDB-GENE-040801-147
• Length: 581
• Species: Danio rerio
• Alignment Length: 585
• Identity: 240/585 - (41%)
• Similarity: 354/585 - (60%)
• Gaps: 13/585 - (2%)

  Fly     9 LLRLAS--RPLLSSSRRFSVYDDEMEQITRPDWHVVMNGKYNKGLAFTIKERQRLGIMGLMPCSV 71
            |.||::  ||.:|..|  .|:..|.   .:|   :::|.:.|||:|||:||||.|||.||:|..:
Zfish     2 LSRLSTSVRPCVSMCR--WVHTKEK---GKP---LMLNPRTNKGMAFTLKERQMLGIHGLLPSKI 58

  Fly    72 RSMDDQMNAALANFEARPTDIARFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGDVVATY 136
            .:.|.|......|.:.....:.::.||..:..|:.||:||.:.|:||..:|||||||||.....|
Zfish    59 ETQDTQAMRFQKNLKKMSDPLQKYIYLMGIQERNERLFYRVLMEDIEALMPIVYTPTVGLACTQY 123

  Fly   137 GLNFQQAISLFISIHDKGHIRDLMHNWVDEGVKAICVTDGGRVLGLGDMGANAMGISLGKMILYT 201
            |..|::...|||||.|:||||.::.||.|..|||:.||||.|:|||||:|...|||.:||:.|||
Zfish   124 GHIFRRPKGLFISIKDQGHIRSILDNWPDTSVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYT 188

  Fly   202 ALGSIPPSTLMPVCLDVGTDNQALLQDPLYVGARIPRVKGPEYDELVDEFMESAVKCFGNNTFIH 266
            |...|.|.:.:|||:||||||:.||:||.|:|....|.:...||:|:|||||:.|..:|.:|.|.
Zfish   189 ACAGIRPESCLPVCIDVGTDNEKLLRDPFYMGLYQRRDRSQRYDDLIDEFMEAVVDKYGQDTLIQ 253

  Fly   267 FEDFATPNALKFLEKYQYKYCCFNDDIQGTGATGLAAFINVERITGRKLEDTVFLFVGAGSAALG 331
            ||||...||.:||:||:.|||.||||||||.:..||..:..:|..|:.|.:...||:|||.||||
Zfish   254 FEDFGNHNAFRFLKKYREKYCTFNDDIQGTASVALAGLLAAQRAVGKPLTEHKVLFLGAGEAALG 318

  Fly   332 IANMLAMELEVRGIPAEEATKNIYLMDVNGILTPESPNPPEMGKIFIKSMEP--MKDMMAVLKKL 394
            |||::.|.:...|:...:|.|.|::.|..|:|..:.....:..:......:|  :|..:..:..:
Zfish   319 IANLIVMAMMESGMSQADARKKIWMFDKYGLLVKDRAYETDSNQEAFVHPDPGDVKSFLDAVNVI 383

  Fly   395 KPSVLVGATGVGGIFNEEVLKTMAKNHERPAVFPLSNPTANSECTAEQAFTHTEGRVLFGSGSPF 459
            ||:.::|.:|.|.:|..:|:|.|...:|||.:|.||||||.:|||||.|::.|:||.||.|||||
Zfish   384 KPTAIIGVSGAGRLFTHDVIKAMGNLNERPIIFALSNPTAKAECTAEDAYSLTQGRCLFASGSPF 448

  Fly   460 PPVVI-NGKRYRPAQANNCLTFPGIALAAITAKARYLPNEVFSVVSHELARNTPQELLDEGTLFP 523
            .||.: :|:...|.|.||...|||:|||.|.:..|::.:.||...:..||.....|.|.:|.|:|
Zfish   449 APVSLEDGRILTPGQGNNAYIFPGVALAVILSGVRHISDTVFLEAAKTLADQLTDEELSQGRLYP 513

  Fly   524 PIKDAHNVAFNVGVAMTQYLIDNDLSNVYPKPDDICEFVKRSLYKFDYRNSLPTTWDYPVEPPTP 588
            |:.:...|:..:.:.:.:|:....::..||:|.|...:|:..::..:|.:.||..:|:|....||
Zfish   514 PLSNIREVSLQMAIKVVEYVYSKGMAFRYPEPVDKESYVRSVVWNTNYDSFLPDIYDWPGVSHTP 578

  Fly   589  588
            Zfish   579  578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	234/568 (41%)
me2	NP_001003627.2	PLN03129	18..565	CDD:215594	227/552 (41%)