Protein Alignment Menl-2 and CG7848

DIOPT Version :9

• Sequence 1: NP_001027424.2
• Gene: Menl-2 / 3772692
• FlyBaseID: FBgn0029153
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_611127.1
• Gene: CG7848 / 36839
• FlyBaseID: FBgn0034127
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 537
• Identity: 167/537 - (31%)
• Similarity: 286/537 - (53%)
• Gaps: 1/537 - (0%)

  Fly    39 WHVVMNGKYNKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTDIARFTYLSAVHH 103
            | ::....||||||||:.||:.|.|.||:|.:||::|:|........|:...::.::.||:.:..
  Fly    74 W-MLNQSNYNKGLAFTLNERRVLSIHGLLPVAVRTIDEQAEICSNLLESFTNNVQQYIYLTYLSR 137

  Fly   104 RHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNWVDEGV 168
            |:|||:|..:..|.::.:|:.......|::..:.:.......|:|.|.|.||:..::.||....|
  Fly   138 RNRRLFYYLLLSNPDRFVPMTDASGSIDLLMVHRMIHSMGQGLYICIKDLGHVSQILSNWPFRCV 202

  Fly   169 KAICVTDGGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDNQALLQDPLYVG 233
            :.:.|::|..||.:||:|.:.|.|....:......|.|.|:..:.|.|||||:|:.||.||:|.|
  Fly   203 RCLLVSNGASVLSVGDLGVDEMPILFSNLHQNVVYGGIHPAYCLAVMLDVGTNNEELLNDPMYTG 267

  Fly   234 ARIPRVKGPEYDELVDEFMESAVKCFGNNTFIHFEDFATPNALKFLEKYQYKYCCFNDDIQGTGA 298
            .|..|.....||:|.:||..|.::.:|....|..:||....|.|.||.|:.:.|..:.|.|...|
  Fly   268 LRERRCSEKLYDQLFEEFTLSVMQQYGPRALILCKDFEAQKAKKQLELYRERQCIVDVDFQCFAA 332

  Fly   299 TGLAAFINVERITGRKLEDTVFLFVGAGSAALGIANMLAMELEVRGIPAEEATKNIYLMDVNGIL 363
            ..||..|...|:........||||.||.:..:|:|.:..:.|:..|:...:|.:.|:..|.||::
  Fly   333 VALAGVIVCNRLKRVFFSSNVFLFYGAEAINIGMARLCMVLLKREGLIEMKAREKIWFFDANGLV 397

  Fly   364 TPESPNPPEMGKIFIKSMEPMKDMMAVLKKLKPSVLVGATGVGGIFNEEVLKTMAKNHERPAVFP 428
            .....:.||....|....:|:.|::..:::|||::|||.:.:...|..:||:.|.|:.::|.:|.
  Fly   398 VLGRKDIPEELLEFANQRDPILDLVEAIQELKPNILVGGSSLPNTFTPDVLRAMEKSADQPVIFA 462

  Fly   429 LSNPTANSECTAEQAFTHTEGRVLFGSGSPFPPVVINGKRYRPAQANNCLTFPGIALAAITAKAR 493
            ||.|...:||:||.||::|:|..:|.|||..||:....|.|:|....:.....||:...:.|...
  Fly   463 LSRPLEQTECSAEDAFSYTKGHCIFISGSKLPPLKYANKWYQPGHCTSSYLVAGISCGVMLAGFT 527

  Fly   494 YLPNEVFSVVSHELARNTPQELLDEGTLFPPIKDAHNVAFNVGVAMTQYLIDNDLSNVYPKPDDI 558
            .:|:|.|.|.:..||.......|::..::||::....::..:..|:..|.....|:.:||:|::.
  Fly   528 NIPDEAFCVAAERLASLVWPCDLEKRNVYPPMRKIQCISLQIAEAIFSYAFGRGLATLYPQPENP 592

  Fly   559 CEFVKRSLYKFDYRNSL 575
            .|::|.|:|..:||.::
  Fly   593 MEYIKNSMYNPEYRMNI 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	166/533 (31%)
		malic	102..283	CDD:278802	58/180 (32%)
		NADB_Rossmann	293..567	CDD:304358	80/273 (29%)
CG7848	NP_611127.1	PLN03129	81..606	CDD:215594	164/524 (31%)
		malic	138..317	CDD:278802	58/178 (33%)
		NAD_bind_1_malic_enz	327..603	CDD:133454	81/275 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469230
Domainoid	1	1.000	155	1.000	Domainoid score	I893
eggNOG	1	0.900	-	-		E1_COG0281
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	329	1.000	Inparanoid score	I521
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000475
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23406
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X340
	8	7.890