Protein Alignment Menl-2 and Me2

DIOPT Version :10

• Sequence 1: NP_001027424.2
• Gene: Menl-2 / 3772692
• FlyBaseID: FBgn0029153
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_006254985.1
• Gene: Me2 / 307270
• RGDID: 1310321
• Length: 591
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 239/587 - (40%)
• Similarity: 357/587 - (60%)
• Gaps: 21/587 - (3%)

  Fly    10 LRLASRPLLSSSRRFSVYDDEMEQITRPDWHVVMNGKYNKGLAFTIKERQRLGIMGLMPCSVRSM 74
            ||..:.|...:.||.     .:::..:|   :::|.:.|||:|||::|||.||:.||:|..:.:.
  Rat    12 LRAVTTPCTLTCRRV-----HLKEKGKP---LMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQ 68

  Fly    75 DDQMNAALANFEARPTDIARFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLN 139
            |.|......|.:...:.:.::.|:..:..|:.:|:||.::::||..:|||||||||.....||..
  Rat    69 DIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHI 133

  Fly   140 FQQAISLFISIHDKGHIRDLMHNWVDEGVKAICVTDGGRVLGLGDMGANAMGISLGKMILYTALG 204
            |::...|||||.|:||:|.::.||.:..|||:.||||.|:|||||:|...|||.:||:.||||..
  Rat   134 FRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACA 198

  Fly   205 SIPPSTLMPVCLDVGTDNQALLQDPLYVGARIPRVKGPEYDELVDEFMESAVKCFGNNTFIHFED 269
            .|.|...:|||:||||||.|||:||.|:|....|.:...||:|:||||::....:|.||.|.|||
  Rat   199 GIQPEKCLPVCIDVGTDNMALLKDPFYMGLYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFED 263

  Fly   270 FATPNALKFLEKYQYKYCCFNDDIQGTGATGLAAFINVERITGRKLEDTVFLFVGAGSAALGIAN 334
            |...||.:||:|||.|||.||||||||.|..|:..:..:|:..:.:.:...||:|||.||||||.
  Rat   264 FGNHNAFRFLKKYQEKYCTFNDDIQGTAAVALSGLLAAQRVINKPISEHRILFLGAGEAALGIAK 328

  Fly   335 MLAMELEVRGIPAEEATKNIYLMDVNGILTP------ESPNPPEMGKIFIKSMEPMKDMMAVLKK 393
            ::.:.:...|:..|||.:.|::.|.||:|..      :|...|.............:|   .:.|
  Rat   329 LIVISMMESGLSEEEAQRKIWMFDKNGLLVKGRTARIDSNQEPYAHAASENIPATFED---AVNK 390

  Fly   394 LKPSVLVGATGVGGIFNEEVLKTMAKNHERPAVFPLSNPTANSECTAEQAFTHTEGRVLFGSGSP 458
            |||||::|..|.|.:|...|:|.||..:|||.:|.||||||.:|||||.|:|.||||.||.||||
  Rat   391 LKPSVIIGVAGAGPLFTPGVIKAMAAINERPIIFALSNPTAQAECTAEDAYTLTEGRCLFASGSP 455

  Fly   459 FPPVVI-NGKRYRPAQANNCLTFPGIALAAITAKARYLPNEVFSVVSHELARNTPQELLDEGTLF 522
            |.||.: :|:.:.|.|.||...|||:|||.|..:||::.:.||...:..|......|.|.:|.|:
  Rat   456 FEPVRLQDGRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKALTSQLTDEELAQGRLY 520

  Fly   523 PPIKDAHNVAFNVGVAMTQYLIDNDLSNVYPKPDDICEFVKRSLYKFDYRNSLPTTWDYP---VE 584
            |.:.:...|:.|:.:.:.:||..|.::..||:|:|..::||..:::.:|.:.||..:|:|   ::
  Rat   521 PSLANIQEVSANIAIKIAEYLYANKMAFRYPEPEDKAKYVKERIWRSNYVSLLPDVYDWPESSLK 585

  Fly   585 PP 586
            ||
  Rat   586 PP 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	233/569 (41%)
Me2	XP_006254985.1	PLN03129	35..573	CDD:215594	227/540 (42%)