DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Menl-2 and SPAC750.08c

DIOPT Version :9

Sequence 1:	NP_001027424.2	Gene:	Menl-2 / 3772692	FlyBaseID:	FBgn0029153	Length:	600	Species:	Drosophila melanogaster
Sequence 2:	NP_595034.1	Gene:	SPAC750.08c / 2542710	PomBaseID:	SPAC750.08c	Length:	228	Species:	Schizosaccharomyces pombe

Alignment Length:	210	Identity:	64/210 - (30%)
Similarity:	108/210 - (51%)	Gaps:	13/210 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   375 KIFIKSMEPMK-------DMMAVLKKLKPSVLVGATGVGGIFNEEVLKTMAKNHERPAVFPLSNP 432
            |.|:|.....|       |:...:..:||:||:|.:|..|.|.|:.::.|:|:.:.|.:||:|||
pombe    19 KPFLKKDSDFKEVPSGDIDLETAISLIKPTVLLGCSGQPGKFTEKAIREMSKHVKHPIIFPISNP 83

  Fly   433 TANSECTAEQAFTHTEGRVLFGSGSPFPPVVINGKRYRPAQANNCLTFPGIALAAITAKARYLPN 497
            |...|....|....:.|:.|..:|||.||:..|||.|..:|.||.|.:|.:.:|.:.::.:.|.:
pombe    84 TTLMEAKPVQIDEWSNGKALMATGSPLPPLTRNGKEYVISQCNNALLYPALGVACVLSRCKLLSD 148

  Fly   498 EVFSVVSHELARNTPQELL--DEGTLFPPIKDAHNVAFNVGVAMTQYLIDNDLSNV-YPKPD-DI 558
            .:....|..|| ..|:.|.  || .|.|.:.:|..::.::..|:.:..|...:|.| .||.| .:
pombe   149 GMLKAASDALA-TVPRSLFVADE-ALLPDLDNAREISRHIVFAVLKQAISEGMSTVDLPKDDAKL 211

  Fly   559 CEFVKRSLYKFDYRN 573
            .|::....:..:|||
pombe   212 KEWIIEREWNPEYRN 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	62/208 (30%)
		malic	102..283	CDD:278802
		NADB_Rossmann	293..567	CDD:304358	61/202 (30%)
SPAC750.08c	NP_595034.1	NADB_Rossmann	<1..222	CDD:304358	61/204 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	147	1.000	Domainoid score	I1122
eggNOG	1	0.900	-	-		E1_COG0281
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000475
OrthoInspector	1	1.000	-	-		mtm9297
orthoMCL	1	0.900	-	-		OOG6_100205
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.710