Protein Alignment Menl-2 and mae2

DIOPT Version :10

• Sequence 1: NP_001027424.2
• Gene: Menl-2 / 3772692
• FlyBaseID: FBgn0029153
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_587760.1
• Gene: mae2 / 2539592
• PomBaseID: SPCC794.12C
• Length: 565
• Species: Schizosaccharomyces pombe
• Alignment Length: 542
• Identity: 171/542 - (31%)
• Similarity: 291/542 - (53%)
• Gaps: 20/542 - (3%)

  Fly    32 EQITRPDWHVVM--NGKYNKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTD-IA 93
            |||..|...|.:  :.:|||..|||.:|||:..|...:|..|.::..|::.....::|...: :.
pombe     7 EQIECPLKGVTLLNSPRYNKDTAFTPEERQKFEISSRLPPIVETLQQQVDRCYDQYKAIGDEPLQ 71

  Fly    94 RFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYG--LNFQQAISLFISIHDKGHI 156
            :..|||.:...::.|:|..|.:::.:.:||:||||.||.:..:.  ..:.:...|.|..:|..:|
pombe    72 KNLYLSQLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDIDHNDLSYI 136

  Fly   157 RDLMHNW-VDEGVKAICVTDGGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGT 220
            :..:..: ..:.|:.|.:||...:||:||.|...:.||:.|..|.|....:.|:..:|:.|||||
pombe   137 KQQLSEFGKSDSVEYIIITDSEGILGIGDQGVGGVLISVAKGHLMTLCAGLDPNRFLPIVLDVGT 201

  Fly   221 DNQALLQDPLYVGARIPRVKGPEYDELVDEFMESAVKCFGNNTFIHFEDFATPNALKFLEKYQYK 285
            :|:...::..|:|.|..||:|.:||..:|..:::..:.| ...|||||||...||.:.|:.|:..
pombe   202 NNETHRKNHQYMGLRKDRVRGEQYDSFLDNVIKAIREVF-PEAFIHFEDFGLANAKRILDHYRPD 265

  Fly   286 YCCFNDDIQGTGATGLAAFINVERITGRKLEDTVFLFVGAGSAALGIANMLAMELEVRGIPAEEA 350
            ..|||||||||||..|||.|....:|...|.:...:..|||:|.:||||.:...:...|:..::|
pombe   266 IACFNDDIQGTGAVALAAIIGALHVTKSPLTEQRIMIFGAGTAGVGIANQIVAGMVTDGLSLDKA 330

  Fly   351 TKNIYLMDVNGILTPESPNPPEMG-KIFIKSMEPMKD-------MMAVLKKLKPSVLVGATGVGG 407
            ..|::::|..|:|..........| |.|:|.....|:       :.:.:..:||::|:|.:|..|
pombe   331 RGNLFMIDRCGLLLERHAKIATDGQKPFLKKDSDFKEVPSGDINLESAIALVKPTILLGCSGQPG 395

  Fly   408 IFNEEVLKTMAKNHERPAVFPLSNPTANSECTAEQAFTHTEGRVLFGSGSPFPPVVINGKRYRPA 472
            .|.|:.::.|:|:.|||.:||:||||...|...:|....::|:.|..:|||.||:..|||:|..:
pombe   396 KFTEKAIREMSKHVERPIIFPISNPTTLMEAKPDQIDKWSDGKALIATGSPLPPLNRNGKKYVIS 460

  Fly   473 QANNCLTFPGIALAAITAKARYLPNEVFSVVSHELARNTPQELL--DEGTLFPPIKDAHNVAFNV 535
            |.||.|.:|.:.:|.:.::.:.|.:.:....|..|| ..|:.|.  || .|.|.:.:|..::.::
pombe   461 QCNNALLYPALGVACVLSRCKLLSDGMLKAASDALA-TVPRSLFAADE-ALLPDLNNAREISRHI 523

  Fly   536 GVAMTQYLIDNDLSNV-YPKPD 556
            ..|:.:..:...:|.| .||.|
pombe   524 VFAVLKQAVSEGMSTVDLPKDD 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	171/542 (32%)
mae2	NP_587760.1	PRK13529	1..565	CDD:237414	171/542 (32%)