Protein Alignment Menl-2 and Me1

DIOPT Version :10

• Sequence 1: NP_001027424.2
• Gene: Menl-2 / 3772692
• FlyBaseID: FBgn0029153
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_036732.3
• Gene: Me1 / 24552
• RGDID: 3074
• Length: 572
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 242/561 - (43%)
• Similarity: 352/561 - (62%)
• Gaps: 10/561 - (1%)

  Fly    34 ITRPDWHVVMNGKYNKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTDIARFTYL 98
            :|| |.|:      ||.||||::|||:|.|.||:|..:.:.:.|:...:.|||...:|..|:..|
  Rat    18 LTR-DPHL------NKDLAFTLEERQQLNIHGLLPPCIVNQEIQVLRVIKNFERLNSDFDRYLLL 75

  Fly    99 SAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNW 163
            ..:..|:.:|:|..:..|:||.:|||||||||.....|.|.|::...|||||||||||..:::.|
  Rat    76 MDLQDRNEKLFYSVLMSNVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAW 140

  Fly   164 VDEGVKAICVTDGGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDNQALLQD 228
            .::.||||.||||.|:|||||:|.|.|||.:||:.||||.|.:.|...:|:.|||||:|:.||:|
  Rat   141 PEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKD 205

  Fly   229 PLYVGARIPRVKGPEYDELVDEFMESAVKCFGNNTFIHFEDFATPNALKFLEKYQYKYCCFNDDI 293
            |||:|.|..||:|||||..:|||||:|...:|.|..|.|||||..||.:.|.||:.|||.|||||
  Rat   206 PLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANLNAFRLLNKYRNKYCTFNDDI 270

  Fly   294 QGTGATGLAAFINVERITGRKLEDTVFLFVGAGSAALGIANMLAMELEVRGIPAEEATKNIYLMD 358
            |||.:..:|..:...|||..||.|...||.|||.||||||:::.|.:|..|:..|:|.:.|:|:|
  Rat   271 QGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLIVMAMEKEGLSKEKARQKIWLVD 335

  Fly   359 VNGILTPESPNPPEMGKIFIKSMEPMKDMMAVLKKLKPSVLVGATGVGGIFNEEVLKTMAKNHER 423
            ..|::.....:..|..::|....|.||::.|:::|:||:.|:|...:||.|.|::||.||..:||
  Rat   336 SKGLIVKGRASLTEEKEVFAHEHEEMKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNER 400

  Fly   424 PAVFPLSNPTANSECTAEQAFTHTEGRVLFGSGSPFPPVVI-NGKRYRPAQANNCLTFPGIALAA 487
            |.:|.|||||:.:||:||:.:..|:||.:|.|||||.||.: :|:...|.|.||...|||:||..
  Rat   401 PIIFALSNPTSKAECSAEECYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGV 465

  Fly   488 ITAKARYLPNEVFSVVSHELARNTPQELLDEGTLFPPIKDAHNVAFNVGVAMTQYLIDNDLSNVY 552
            :....|::.:.||...:..:::....:.|:||.|:||:....:|:..:.|.:.|......::.||
  Rat   466 VACGLRHINDSVFLTTAEVISQQVSDKHLEEGRLYPPLNTIRDVSLKIAVKIVQDAYKEKMATVY 530

  Fly   553 PKPDDICEFVKRSLYKFDYRNSLPTTWDYPVEPPTPKPKTK 593
            |:|.:..|||...:|..:|...||..:.:|.|  ..|.:||
  Rat   531 PEPQNKEEFVSSQMYSTNYDQILPDCYSWPEE--VQKIQTK 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	235/539 (44%)
Me1	NP_036732.3	PLN03129	11..551	CDD:215594	235/539 (44%)